Project Details
| Short title | The impact of non-histone protein methylation by set1a in maintaining genome stability and preventing disease |
|---|---|
| Status | Finished |
| Effective start/end date | 1/04/17 → 31/03/23 |
Funding
- Medical Research Council
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Research output
- 5 Article
-
SETD1A-dependent EME1 transcription drives PARPi sensitivity in HR deficient tumour cells
Sweatman, E., Bayley, R., Selemane, R. & Higgs, M., 3 May 2025, In: British Journal of Cancer. 132, p. 690-702 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Downloads (Pure) -
New perspectives on epigenetic modifications and PARP inhibitor resistance in HR-deficient cancers
Bayley, R., Sweatman, E. & Higgs, M., 4 Jan 2023, In: Cancer drug resistance (Alhambra, Calif.). 6, p. 35-44 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile81 Downloads (Pure) -
H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ
Bayley, R., Borel, V., Moss, R., Sweatman, E., Ruis, P., Ormrod, A., Goula, A., Mottram, R., Stanage, T., Hewitt, G., Saponaro, M., Stewart, G., Boulton, S. & Higgs, M., 19 May 2022, In: Molecular Cell. 82, 10, p. 1924-1939.e10 26 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)265 Downloads (Pure)