The genetics of the Drosophila mitochondrial DNA and its influence on evolution and diesease

Ma, Hansong (Principal Investigator)

Biosciences

Short title	The genetics of the Drosophila mitochondrial DNA and its influence on evolution and diesease
Status	Finished
Effective start/end date	1/05/23 → 2/01/26

Funding

The Wellcome Trust

4 Article

Single-molecule mitochondrial DNA imaging reveals heteroplasmy dynamics shaped by developmental bottlenecks and selection in vivo
Chandrasegaram, R., Gottardo, S., Dhawanjewar, A., Hynes-Allen, A. M., Gao, B., Chowdhury, S. R., Tábara, L.-C., Frison, M., Pretridi, S., Chinnery, P. F., Prudent, J., Ma, H. & van den Ameele, J., 13 May 2026, In: Developmental Cell. 61, 5, p. 1146-1161.e1-e8 24 p.
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Poldip2 promotes mtDNA elimination during Drosophila spermatogenesis to ensure maternal inheritance
Wang, Z., Meerod, T., Cortes-Silva, N., Chiang, C.-Y., Nie, Z., Di, Y., Mu, P., Verma, A., Reid, A. & Ma, H., 11 Feb 2025, (E-pub ahead of print) In: The EMBO journal.
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Replication competition drives the selective mtDNA inheritance in Drosophila ovary
Zhang, C., Chen, Z., Ma, H. & Xu, H., 23 Sept 2025, In: Cell Reports. 44, 9, 16 p., 116221.
Research output: Contribution to journal › Article › peer-review

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