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Tetraspanin Superfamily Proteins in Megakaryocytes and Platelets
Tomlinson, Michael
(Principal Investigator)
Biosciences
Overview
Fingerprint
Research output
(7)
Project Details
Short title
Tetraspanin Superfamily Proteins in Megakaryocytes and Platelets
Status
Finished
Effective start/end date
1/04/05
→
31/03/08
Funding
Medical Research Council
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Blood Platelets
Medicine & Life Sciences
100%
Tyrosine
Medicine & Life Sciences
73%
C-Type Lectins
Medicine & Life Sciences
56%
Glycoproteins
Medicine & Life Sciences
55%
Platelet Activation
Medicine & Life Sciences
37%
platelet membrane glycoprotein VI
Medicine & Life Sciences
35%
Amino Acid Motifs
Medicine & Life Sciences
35%
Immunoreceptor Tyrosine-Based Activation Motif
Medicine & Life Sciences
35%
Research output
Research output per year
2006
2007
2009
2009
7
Article
Research output per year
Research output per year
Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains
Protty, M.
,
Watkins, N.
,
Colombo, D.
,
Thomas, S.
,
Heath, V.
,
Herbert, J.
,
Bicknell, R.
,
Senis, Y.
,
Ashman, L.
,
Berditchevski, F.
,
Ouwehand, W.
,
Watson, S.
&
Tomlinson, M.
,
1 Jan 2009
,
In:
Biochemical Journal.
417
,
1
,
p. 391-
Research output
:
Contribution to journal
›
Article
›
peer-review
File
platelet membrane glycoprotein VI
100%
Tetraspanins
85%
Collagen
55%
Blood Platelets
45%
Microarrays
31%
51
Citations (Scopus)
121
Downloads (Pure)
The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis
Senis, Y.
,
Tomlinson, M.
,
Ellison, S.
,
Mazharian, A.
,
Lim, J.
,
Zhao, Y.
,
Kornerup, K.
,
Auger, J.
,
Thomas, S.
,
Dhanjal, T.
,
Kalia, N.
,
Zhu, JW.
,
Weiss, A.
&
Watson, S.
,
14 May 2009
,
In:
Blood.
113
,
20
,
p. 4942-4954
13 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Platelet Activation
100%
Phosphoric Monoester Hydrolases
92%
Agonist
86%
src-Family Kinases
86%
Tyrosine
83%
94
Citations (Scopus)
258
Downloads (Pure)
G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2.
Mori, J.
,
Pearce, AC.
,
Spalton, J.
,
Grygielska, B.
,
Eble, JA.
,
Tomlinson, M.
,
Senis, Y.
&
Watson, S.
,
19 Dec 2008
,
In:
Journal of Biological Chemistry.
283
,
51
,
p. 35419-27
9 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
File
C-Type Lectins
100%
Tyrosine
68%
Glycoprotein
68%
Syk Kinase
65%
Glycoproteins
63%
54
Citations (Scopus)
204
Downloads (Pure)