Research output per year
Research output per year
- 14 results
Search results
-
2026
Claudin 1-mediated positioning of DC1 to mTECs is essential for maintenance of central tolerance
Březina, J., Brabec, T., Machač, D., Vobořil, M., Ballek, O., Pačes, J., Sýkora, V., Jančovičová, K., Valter, E., Kováčová, K., Manning, J., Tahtahová, V., Čepková, A., Dobešová, M., Dobeš, J., Kubovčiak, J., Kolář, M., Kašpárek, P., Sedlacek, R. & Štepánek, O. & 5 others, , 2 Mar 2026, In: The Journal of Experimental Medicine. 223, 3, 29 p., e20250970.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure) -
2025
Establishment of a microwell-array-based miniaturized thymic organoid model suitable for high-throughput applications
Major, V., Palmer, S., Rouse, P., Morys, J., Henderson, T., Hübscher, T., Sweetman, J., Bacon, A., An, C., Guiyun, Q., Wang, Y., Corsinotti, A., Cholewa-Waclaw, J., Chapman, S. J., Lütolf, M. P., Anderson, G. & Blackburn, C. C., 27 May 2025, In: Cell Reports. 44, 5, 23 p., 115579.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Downloads (Pure) -
Regulatory T cell stability determines the efficiency of bile duct regeneration during cholangitis
Kimura, N., Wong, M. C., Higgins, B., Hardisty, G., Huang, P.-C., Muller, M., Besh, M., Patten, D. A., Kendall, T., Ramachandran, P., Rossi, A. G., Anderson, G., Shetty, S., Withers, D., Tsuchiya, A., Terai, S. & Lu, W.-Y., 25 Nov 2025, In: Cell Reports. 44, 11, 22 p., 116557.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Downloads (Pure) -
2024
Age‐related loss of intestinal barrier integrity plays an integral role in thymic involution and T cell ageing
Conway, J., De Jong, E. N., White, A. J., Dugan, B., Paddison Rees, N., Parnell, S. M., Lamberte, L. E., Sharma‐Oates, A., Sullivan, J., Mauro, C., van Schaik, W., Anderson, G., Bowdish, D. M. E. & Duggal, N. A., 15 Nov 2024, (E-pub ahead of print) In: Aging Cell. 19 p., e14401.Research output: Contribution to journal › Article › peer-review
Open AccessFile205 Downloads (Pure) -
CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages
Mohamed, S. H., Vanhoffelen, E., Shun Fu, M., Hei Lau, P., Hain, S., Seldeslachts, L., Cosway, E., Anderson, G., McCulloch, L., Vande Velde, G. & Drummond, R. A., 20 Aug 2024, (E-pub ahead of print) In: Mucosal immunology. 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile91 Downloads (Pure) -
Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium
Ohigashi, I., White, A. J., Yang, M.-T., Fujimori, S., Tanaka, Y., Jacques, A., Kiyonari, H., Matsushita, Y., Turan, S., Kelly, M. C., Anderson, G. & Takahama, Y., 11 Mar 2024, In: eLife. 12, 24 p., 92552.Research output: Contribution to journal › Article › peer-review
Open AccessFile85 Downloads (Pure) -
European Society of Immunodeficiencies guidelines for the management of patients with congenital athymia
Kreins, A. Y., Dhalla, F., Flinn, A. M., Howley, E., Ekwall, O., Villa, A., Staal, F. J., Anderson, G., Gennery, A. R., Holländer, G. A., Davies, E. G. & European Society of Immunodeficiencies Clinical Working Party, 18 Sept 2024, (E-pub ahead of print) In: Journal of Allergy and Clinical Immunology.Research output: Contribution to journal › Article › peer-review
Open Access -
NUDCD3 deficiency disrupts V(D)J recombination to cause SCID and Omenn syndrome
Chen, R., Lukianova, E., van der Loeff, I. S., Spegarova, J. S., Willet, J. D. P., James, K. D., Ryder, E. J., Griffin, H., IJspeert, H., Gajbhiye, A., Lamoliatte, F., Marin-Rubio, J. L., Woodbine, L., Lemos, H., Swan, D. J., Pintar, V., Sayes, K., Ruiz-Morales, E. R., Eastham, S. & Dixon, D. & 17 others, , 24 May 2024, In: Science Immunology. 9, 95, 17 p., eade5705.Research output: Contribution to journal › Article › peer-review
Open AccessFile190 Downloads (Pure) -
2023
Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk
White, A. J., Parnell, S. M., Handel, A., Maio, S., Bacon, A., Cosway, E. J., Lucas, B., James, K. D., Cowan, J. E., Jenkinson, W. E., Hollander, G. A. & Anderson, G., 1 Jan 2023, In: Journal of Immunology. 210, 1, p. 40-49 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile94 Downloads (Pure) -
Embryonic keratin19+ progenitors generate multiple functionally distinct progeny to maintain epithelial diversity in the adult thymus medulla
Lucas, B., White, A. J., Klein, F., Veiga-Villauriz, C., Handel, A., Bacon, A., Cosway, E. J., James, K. D., Parnell, S. M., Ohigashi, I., Takahama, Y., Jenkinson, W. E., Hollander, G. A., Lu, W.-Y. & Anderson, G., 12 Apr 2023, In: Nature Communications. 14, 1, 14 p., 2066.Research output: Contribution to journal › Article › peer-review
Open AccessFile74 Downloads (Pure) -
The alarmin IL33 orchestrates type 2 immune-mediated control of thymus regeneration
Cosway, E. J., James, K. D., White, A. J., Parnell, S. M., Bacon, A., McKenzie, A. N. J., Jenkinson, W. E. & Anderson, G., 8 Nov 2023, In: Nature Communications. 14, 1, 11 p., 7201.Research output: Contribution to journal › Article › peer-review
Open AccessFile151 Downloads (Pure) -
The medulla controls effector primed γδT-cell development in the adult mouse thymus
James, K. D., White, A. J., Jenkinson, W. E. & Anderson, G., 6 Jun 2023, In: European Journal of Immunology. 53, 6, e2350388.Research output: Contribution to journal › Article › peer-review
Open AccessFile75 Downloads (Pure) -
2022
Eosinophils are an essential element of a type 2 immune axis that controls thymus regeneration
Cosway, E. J., White, A. J., Parnell, S. M., Schweighoffer, E., Jolin, H. E., Bacon, A., Rodewald, H. R., Tybulewicz, V., McKenzie, A. N. J., Jenkinson, W. E. & Anderson, G., 11 Mar 2022, In: Science Immunology. 7, 69, 12 p., eabn3286.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
2021
FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency
Rota, I. A., Handel, A. E., Maio, S., Klein, F., Dhalla, F., Deadman, M. E., Cheuk, S., Newman, J. A., Michaels, Y. S., Zuklys, S., Prevot, N., Hublitz, P., Charles, P. D., Gkazi, A. S., Adamopoulou, E., Qasim, W., Davies, E. G., Hanson, I., Pagnamenta, A. T. & Camps, C. & 11 others, , 3 Dec 2021, In: Science Advances. 7, 49, 19 p., eabj9247.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)184 Downloads (Pure)