Targeting New Mechanisms In The Control Of Thymus Function To Restore Balanced T-cell Production

Anderson, Graham (Principal Investigator)

Immunology and Immunotherapy

Short title	Targeting New Mechanisms In The Control Of Thymus Function To Restore Balanced T-cell Production
Status	Active
Effective start/end date	1/01/21 → 31/12/27

Funding

Medical Research Council

14 Article
3 Review article
1 Preprint

Claudin 1-mediated positioning of DC1 to mTECs is essential for maintenance of central tolerance
Březina, J., Brabec, T., Machač, D., Vobořil, M., Ballek, O., Pačes, J., Sýkora, V., Jančovičová, K., Valter, E., Kováčová, K., Manning, J., Tahtahová, V., Čepková, A., Dobešová, M., Dobeš, J., Kubovčiak, J., Kolář, M., Kašpárek, P., Sedlacek, R. & Štepánek, O. & 5 others, Černý, J., Tsukita, S., Malissen, B., Anderson, G. & Filipp, D., 2 Mar 2026, In: The Journal of Experimental Medicine. 223, 3, 29 p., e20250970.
Research output: Contribution to journal › Article › peer-review

Open Access
File
7 Downloads (Pure)
When immunity multitasks: type 2 pathways power thymus regeneration
Anderson, G., Jun 2026, In: Immunology Letters. 279, 7 p., 107155.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
15 Downloads (Pure)
Establishment of a microwell-array-based miniaturized thymic organoid model suitable for high-throughput applications
Major, V., Palmer, S., Rouse, P., Morys, J., Henderson, T., Hübscher, T., Sweetman, J., Bacon, A., An, C., Guiyun, Q., Wang, Y., Corsinotti, A., Cholewa-Waclaw, J., Chapman, S. J., Lütolf, M. P., Anderson, G. & Blackburn, C. C., 27 May 2025, In: Cell Reports. 44, 5, 23 p., 115579.
Research output: Contribution to journal › Article › peer-review

Open Access
File
20 Downloads (Pure)