Sample Size guidance for UPDATing clinical prediction models to Ensure their accuracy and fairness in practice (SS-UPDATE)

Nirantharakumar, Krishnarajah (Co-Investigator)
Ensor, Joie (Co-Investigator)
Snell, Kym (Co-Investigator)
Denniston, Alastair (Co-Investigator)
Riley, Richard (Principal Investigator)
Adderley, Nicki (Co-Investigator)
Alderman, Joseph (Co-Investigator)
Archer, Lucinda (Co-Investigator)
Collins, Gary (Co-Investigator)

Applied Health Sciences

Short title	Sample Size guidance for UPDATing clinical prediction models to Ensure their accuracy and fairness in practice (SS-UPDATE)
Status	Active
Effective start/end date	15/04/24 → 14/04/27

Funding

Medical Research Council

7 Article
4 Preprint
2 Review article

A decomposition of Fisher’s information to inform sample size for developing or updating fair and precise clinical prediction models – part 3: continuous outcomes
Whittle, R., Riley, R. D., Archer, L., Collins, G. S., Legha, A., Snell, K. I. & Ensor, J., Dec 2026, In: Diagnostic and Prognostic Research. 10, 1, 13 p., 11.
Research output: Contribution to journal › Article › peer-review

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A general sample size framework for developing or updating a predictive algorithm: with application to clinical prediction models
Riley, R. D., Whittle, R., Sadatsafavi, M., Martin, G. P., Pate, A., Collins, G. S. & Ensor, J., 29 Apr 2026, (E-pub ahead of print) In: BMC Medical Research Methodology.
Research output: Contribution to journal › Article › peer-review

Open Access
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Bayesian Sample Size Calculations for External Validation Studies of Risk Prediction Models
Sadatsafavi, M., Gustafson, P., Setayeshgar, S., Wynants, L. & Riley, R. D., 11 Feb 2026, (E-pub ahead of print) In: Statistics in Medicine. 45, 3-5, 15 p., e70389.
Research output: Contribution to journal › Article › peer-review

Open Access
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18 Downloads (Pure)