Remission induction of arthritis caused by cancer immunotherapy [REACT]: a randomised multicentre trial to guide initial therapy for checkpoint inhibitor [CPI] induced arthritis

Rowe, Anna (Co-Investigator)
Filer, Andrew (Co-Investigator)
Homer, Victoria (Co-Investigator)
Fisher, Benjamin (Principal Investigator)

Short title	Remission induction of arthritis caused by cancer immunotherapy [REACT]: a randomised multicentre trial to guide initial therapy for checkpoint inhibitor [CPI] induced arthritis
Status	Active
Effective start/end date	1/09/23 → 31/08/28

Funding

NIHR

1 Article

Pragmatic, open-label, multicentre, randomised controlled trial to guide initial therapy for immune checkpoint inhibitor-induced inflammatory arthritis comparing standard of care (prednisolone) to adalimumab without glucocorticoids: REACT trial protocol
Fisher, B. A., Rowe, A., Hodson, C., Wilkhu, M., Williams, E., Turner, E., Allard, A., Blake, T., Bombardieri, M., Cope, A. P., Dubey, S., Mankia, K., Malley, T., Moore, O., Payne, M., Plummer, R., Tilby, M., Tillett, T., Wong, E. & Wu, Y. & 4 others, Filer, A., Pratt, A., Pallan, L. & Homer, V., 3 Mar 2026, In: BMJ Open. 16, 3, 10 p., e116847.
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