Psychosis Immune Mechanism Stratified Medicine Study (PIMS)

Upthegrove, Rachel (Principal Investigator)
Wood, Stephen (Co-Investigator)
Gkoutos, Georgios (Co-Investigator)
Barnes, Nicholas (Researcher)

Short title	Psychosis Immune Mechanism Stratified Medicine Study (PIMS)
Status	Active
Effective start/end date	1/12/19 → 30/04/27

Funding

Medical Research Council

Cardiometabolic prediction models for young people with psychosis spectrum disorders in the UK (PsyMetRiC 2.0): a retrospective, multicohort clinical prediction model study
Perry, B. I., Osimo, E. F., Si, S., Hitchins, K. V. B., Lewis, C., Laws, B., Griffin, S. J., Khandaker, G. M., Murray, G. K., Shiers, D., Chew-Graham, C. A., Jones, P. B., Denniston, A. K., Bardus, M., Jowett, S., Walsh, A. E. L., Arshad, S., Formanek, T., Pillinger, T. & McCutcheon, R. A. & 7 others, Holt, R. I. G., Heyse, S., Rambousek, M., Whiteley, K., Upthegrove, R., Ensor, J. & The PsyMetRiC Network, 11 Mar 2026, (E-pub ahead of print) In: The Lancet Psychiatry. 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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3 Downloads (Pure)
Depressive and negative symptoms in the early and established stages of schizophrenia: integrating structural brain alterations, cognitive performance, and plasma interleukin-6 levels
Corsi-Zuelli, F., Donohoe, G., Griffiths, S., Del-Ben, C. M., Watson, A. J., Burke, T., Lalousis, P. A., McKernan, D., Morris, D., Kelly, J. P., McDonald, C., Patlola, S. R., Pariante, C. M., Barnes, N., Khandaker, G. M., Suckling, J., Deakin, B., Upthegrove, R. & Dauvermann, M., Mar 2025, In: Biological Psychiatry Global Open Science. 5, 2, 100429.
Research output: Contribution to journal › Article › peer-review

Open Access
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80 Downloads (Pure)
Multivariate Brain-Blood Signatures in Early-Stage Depression and Psychosis
Popovic, D., Weyer, C., Dwyer, D. B., Griffiths, S. L., Lalousis, P. A., Barnes, N. M., Vetter, C., Neuner, L.-M., Buciuman, M.-O., Sarisik, E., Paolini, M., Lichtenstein, T., Kambeitz-Ilankovic, L., Kambeitz, J., Ruhrmann, S., Chisholm, K., Schultze-Lutter, F., Falkai, P., Schiltz, K. & Steiner, J. & 16 others, Ziller, M., Pergola, G., Blasi, G., Bertolino, A., Romer, G., Lencer, R., Dannlowski, U., Salokangas, R. K. R., Pantelis, C., Brambilla, P., Borgwardt, S., Wood, S. J., Meisenzahl, E., Koutsouleris, N., Upthegrove, R. & PRONIA Consortium, 17 Dec 2025, (E-pub ahead of print) In: JAMA psychiatry. 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
3 Downloads (Pure)

Psychosis Immune Mechanism Stratified Medicine Study (PIMS)

Project Details

Funding

Fingerprint

Cardiometabolic prediction models for young people with psychosis spectrum disorders in the UK (PsyMetRiC 2.0): a retrospective, multicohort clinical prediction model study

Depressive and negative symptoms in the early and established stages of schizophrenia: integrating structural brain alterations, cognitive performance, and plasma interleukin-6 levels

Multivariate Brain-Blood Signatures in Early-Stage Depression and Psychosis

Psychosis Immune Mechanism Stratified Medicine Study (PIMS)

Project Details

Funding

Fingerprint

Research output

Cardiometabolic prediction models for young people with psychosis spectrum disorders in the UK (PsyMetRiC 2.0): a retrospective, multicohort clinical prediction model study

Depressive and negative symptoms in the early and established stages of schizophrenia: integrating structural brain alterations, cognitive performance, and plasma interleukin-6 levels

Multivariate Brain-Blood Signatures in Early-Stage Depression and Psychosis