Platelet Endothelial Aggregation Receptor 1

Watson, Steve (Principal Investigator)

Cardiovascular Sciences

Short title	Platelet Endothelial Aggregation Receptor 1
Status	Finished
Effective start/end date	1/10/20 → 30/09/22

Funding

European Commission

Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2 and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand
Martin, E., Clark, J., Montague, S., Moran, L. A., Di, Y., Bull, L. J., Whittle, L., Raka, F., Buka, R., Zafar, I., Kardeby, C., Slater, A. & Watson, S., 1 Jan 2024, In: Journal of Thrombosis and Haemostasis. 22, 1, p. 271-285
Research output: Contribution to journal › Article › peer-review

Open Access
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Heparin and heparin proteoglycan-mimetics activate platelets via PEAR1 and PI3Kβ
Kardeby, C., Evans, A., Campos, J., Al-Wahaibi, A. M., Smith, C., Slater, A., Martin, E., Severin, S., Brill, A., Pejler, G., Sun, Y. & Watson, S., 1 Jan 2023, In: Journal of Thrombosis and Haemostasis. 21, 1, p. 101-116 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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88 Downloads (Pure)
Anti-platelet drugs block platelet activation by vaccine-induced immune thrombocytopenia and thrombosis patient serum
Smith, C., Montague, S., Kardeby, C., Di, Y., Lowe, G., Lester, W., Watson, S. & Nicolson, P., 10 Aug 2021, (E-pub ahead of print) In: Blood.
Research output: Contribution to journal › Letter › peer-review

Open Access
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64 Downloads (Pure)