Pharmaceutical targeting of RAS in Acute Myeloid Leukaemia with RAS mutations or FLT3-ITD

Coleman, Daniel (Principal Investigator)

Cancer and Genomic Sciences

Short title	Pharmaceutical targeting of RAS in Acute Myeloid Leukaemia with RAS mutations or FLT3-ITD
Status	Finished
Effective start/end date	1/01/22 → 29/02/24

Funding

LEUKAEMIA UK

2 Article

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth
Kellaway, S. G., Potluri, S., Keane, P., Blair, H. J., Ames, L., Worker, A., Chin, P. S., Ptasinska, A., Derevyanko, P. K., Adamo, A., Coleman, D. J. L., Khan, N., Assi, S. A., Krippner-Heidenreich, A., Raghavan, M., Cockerill, P. N., Heidenreich, O. & Bonifer, C., 14 Feb 2024, In: Nature Communications. 15, 1, 22 p., 1359.
Research output: Contribution to journal › Article › peer-review

Open Access
File
13 Downloads (Pure)
Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth
Coleman, D. J. L., Keane, P., Luque-Martin, R., Chin, P. S., Blair, H., Ames, L., Kellaway, S. G., Griffin, J., Holmes, E., Potluri, S., Assi, S. A., Bushweller, J., Heidenreich, O., Cockerill, P. N. & Bonifer, C., 26 Dec 2023, In: Cell Reports. 42, 12, 113568.
Research output: Contribution to journal › Article › peer-review

Open Access
File