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Novel hybrid anti-MRSA antibiotics from manipulation of the mupirocin and thiomarinol biosynthetic pathways
Thomas, Chris
(Principal Investigator)
Winn, Peter
(Co-Investigator)
Biosciences
Overview
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Research output
(7)
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Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Medicine & Life Sciences
Mupirocin
100%
thiomarinol
55%
Polyketides
51%
Polyketide Synthases
47%
Pseudomonas fluorescens
42%
Anti-Bacterial Agents
39%
pseudomonic acid I
33%
Acyl Carrier Protein
21%
Multigene Family
16%
Mixed Function Oxygenases
15%
Pseudomonas
15%
Hydroxyl Radical
11%
Plasmids
11%
Biosynthetic Pathways
9%
Genes
8%
epoxidase
8%
Hydroxylation
7%
Mutation
7%
Transfer RNA
7%
Alkenes
7%
Poisoning
6%
Epoxy Compounds
6%
Methicillin-Resistant Staphylococcus aureus
5%
Pyrans
5%
Chemistry
Mupirocin
42%
Polyketide
32%
Antimicrobial Agent
14%
Biosynthesis
11%
Thiomarinol A
10%
Metabolite
9%
Pyran Ring
6%
Metabolic
5%
Acid
5%