Negative feedback control of T cells in tolerance and cancer - from pathways to biomarkers

Bending, David (Principal Investigator)

Immunology and Immunotherapy

Short title	Negative feedback control of T cells in tolerance and cancer - from pathways to biomarkers
Status	Active
Effective start/end date	1/02/21 → 31/01/27

Funding

Medical Research Council

15 Article
4 Preprint
1 Comment/debate
1 Review article

A pan-immunotherapy signature to predict intratumoral CD8⁺ T cell expansions
Takahashi, M., Tsunoda, M., Aoki, H., Kurosu, M., Ogiwara, H., Shichino, S., Bending, D., Ishikawa, S., Thaventhiran, J. E. D., Matsushima, K. & Ueha, S., 20 Oct 2025, In: Nature Communications. 16, 1, 14 p., 9175.
Research output: Contribution to journal › Article › peer-review

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Interferon-γ and IL-27 positively regulate type 1 regulatory T-cell development during adaptive tolerance
Lecky, D., Sheriff, L., Rouvray, S., George, L. S., Copland, A., Drummond, R., Wraith, D. & Bending, D., 28 Mar 2025, (E-pub ahead of print) In: iScience. 112308.
Research output: Contribution to journal › Article › peer-review

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Lag3 and PD-1 pathways preferentially regulate NFAT-dependent TCR signalling programmes during early CD4⁺ T cell activation
Sheriff, L., Copland, A., Lecky, D., Done, R., George, L. S., Jennings, E., Rouvray, S., Elliot, T., Jinks, E., Pallan, L. & Bending, D., 11 May 2025, In: Immunotherapy Advances. 5, 1, 15 p., ltaf015.
Research output: Contribution to journal › Article › peer-review

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