National Lung Matrix Trial: Multi-drug, genetic marker-directed, non-comparative, multi-centre, multi-arm phase II trial in non-small cell lung cancer

Billingham, Lucinda (Co-Investigator)
Steven, Neil (Co-Investigator)
Middleton, Gary (Principal Investigator)

Short title	National Lung Matrix Trial: Multi-drug, genetic marker-directed, non-comparative, multi-centre, multi-arm phase II trial in non-small cell lung cancer
Status	Finished
Effective start/end date	1/10/16 → 30/04/25

Funding

Cancer Research Uk

2 Article

A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer
Middleton, G., Robbins, H. L., Fletcher, P., Savage, J., Mehmi, M., Summers, Y., Greystoke, A., Steele, N., Popat, S., Jain, P., Spicer, J., Cave, J., Shaw, P., Gilligan, D., Power, D., Fennell, D., Bajracharya, M., Mcbride, D. J., Maheswari, U. & Frankell, A. M. & 3 others, Swanton, C., Beggs, A. D. & Billingham, L., 11 Mar 2025, In: npj Precision Oncology. 9, 1, 11 p., 67.
Research output: Contribution to journal › Article › peer-review

Open Access
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The National Lung Matrix Trial of personalized therapy in lung cancer
Middleton, G., Fletcher, P., Popat, S., Savage, J., Summers, Y., Greystoke, A., Gilligan, D., Cave, J., O’rourke, N., Brewster, A., Toy, E., Spicer, J., Jain, P., Dangoor, A., Mackean, M., Forster, M., Farley, A., Wherton, D., Mehmi, M. & Sharpe, R. & 7 others, Mills, T. C., Cerone, M. A., Yap, T. A., Watkins, T. B. K., Lim, E., Swanton, C. & Billingham, L., 30 Jul 2020, In: Nature. 583, 7818, p. 807-812 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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14 Citations (Scopus)

572 Downloads (Pure)