Mycobacterium tuberculosis capsular alpha-glucan biosynthesis and characterisation of host-pathogen

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2012
Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation
Mishra, A. K., Alves, J. E., Krumbach, K., Nigou, J., Castro, A. G., Geurtsen, J., Eggeling, L., Saraiva, M. & Besra, G. S., 2012, In: Journal of Biological Chemistry. 287, 53, p. 44173-83 11 p.
Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus)
Ppm1-encoded polyprenyl monophosphomannose synthase activity is essential for lipoglycan synthesis and survival in mycobacteria
Rana, A. K., Singh, A., Gurcha, S. S., Cox, L. R., Bhatt, A. & Besra, G. S., 2012, In: PLoS ONE. 7, 10, p. e48211
Research output: Contribution to journal › Article › peer-review

Open Access
20 Citations (Scopus)
2010
Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an alpha-glucan pathway
Kalscheuer, R., Syson, K., Veeraraghavan, U., Weinrick, B., Biermann, KE., Liu, Z., Sacchettini, JC., Besra, G., Bornemann, S. & Jacobs, WR., 1 May 2010, In: Nature Chemical Biology. 6, 5, p. 376-384 9 p.
Research output: Contribution to journal › Article
116 Citations (Scopus)
Trehalose-recycling ABC transporter LpqY-SugA-SugB-SugC is essential for virulence of Mycobacterium tuberculosis
Kalscheuer, R., Weinrick, B., Veeraraghavan, U., Besra, G. & Jacobs, WR., 14 Dec 2010, In: National Academy of Sciences. Proceedings. 107, 50, p. 21761-6 6 p.
Research output: Contribution to journal › Article
106 Citations (Scopus)

Research output