MICA: Addressing the burgeoning problem of tuberculosis: Exploiting phenotypic hits to identify new protein targets for drug discovery

Besra, Del (Principal Investigator)
Cox, Liam (Co-Investigator)
Futterer, Klaus (Co-Investigator)

Short title	MICA: Addressing the burgeoning problem of tuberculosis: Exploiting phenotypic hits to identify new protein targets for drug discovery
Status	Finished
Effective start/end date	1/04/18 → 31/03/22

Funding

Medical Research Council

10 Article
3 Review article

Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis
Gao, S., Wu, F., Gurcha, S. S., Batt, S. M., Besra, G. S., Rao, Z. & Zhang, L., 15 Mar 2024, (E-pub ahead of print) In: Nature Microbiology.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Top five unanswered questions in bacterial cell wall research
Batt, S. M., Abrahams, K. A. & Besra, G. S., Jun 2024, In: The Cell Surface. 11, 4 p., 100122.
Research output: Contribution to journal › Review article › peer-review

Open Access
File

10 Downloads (Pure)
Assay development and inhibition of the Mt-DprE2 essential reductase from Mycobacterium tuberculosis
Batt, S. M., Toth, S., Rodriguez, B., Abrahams, K. A., Veerapen, N., Chiodarelli, G., Cox, L. R., Moynihan, P. J., Lelievre, J., Fütterer, K. & Besra, G. S., 23 Jan 2023, In: Microbiology. 169, 1, 001288.
Research output: Contribution to journal › Article › peer-review

Open Access
File
37 Downloads (Pure)