KTP - Cobra Biologics Ltd - Development of innovative screening procedures and high productivity expression and fermentation processes for the production of novel therapeutics proteins in microbial systems

Overton, Tim (Principal Investigator)

Chemical Engineering

3 Article

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2023
Optimisation of recombinant TNFα production in Escherichia coli using GFP fusions and flow cytometry
Zulkifly, A., Selas Castineiras, T. & Overton, T., 2 Aug 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 12 p., 1171823.
Research output: Contribution to journal › Article › peer-review

Open Access
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35 Downloads (Pure)
2018
Development of a generic β-lactamase screening system for improved signal peptides for periplasmic targeting of recombinant proteins in Escherichia coli
Selas Castineiras, T., Williams, S., Hitchcock, A., Cole, J., Smith, D. & Overton, T., 3 May 2018, In: Scientific Reports. 8, 6986.
Research output: Contribution to journal › Article › peer-review

Open Access
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10 Citations (Scopus)

158 Downloads (Pure)
Optimising host cell physiology and stress avoidance for the production of recombinant human tumour necrosis factor α in Escherichia coli
Selas Castineiras, T., Williams, S., Hitchcock, A., Cole, J., Smith, D. & Overton, T., 1 Apr 2018, In: Microbiology. 164, p. 440-452
Research output: Contribution to journal › Article › peer-review

Open Access
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3 Citations (Scopus)

277 Downloads (Pure)