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KTP - Cobra Biologics Ltd - Development of innovative screening procedures and high productivity expression and fermentation processes for the production of novel therapeutics proteins in microbial systems
Overton, Tim
(Principal Investigator)
Chemical Engineering
Overview
Fingerprint
Research output
(3)
Research output
Research output per year
2018
2018
2023
2023
3
Article
Research output per year
Research output per year
3 results
Publication Year, Title
(descending)
Publication Year, Title
(ascending)
Title
Type
Search results
2023
Optimisation of recombinant TNFα production in
Escherichia coli
using GFP fusions and flow cytometry
Zulkifly, A.
,
Selas Castineiras, T.
&
Overton, T.
,
2 Aug 2023
,
In:
Frontiers in Bioengineering and Biotechnology.
11
,
12 p.
, 1171823.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Flow cytometry
100%
Escherichia coli
84%
Green Fluorescent Proteins
71%
Cytometry
69%
Proteins
61%
35
Downloads (Pure)
2018
Development of a generic β-lactamase screening system for improved signal peptides for periplasmic targeting of recombinant proteins in
Escherichia coli
Selas Castineiras, T.
,
Williams, S.
,
Hitchcock, A.
,
Cole, J.
,
Smith, D.
&
Overton, T.
,
3 May 2018
,
In:
Scientific Reports.
8
, 6986.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
recombinant proteins
100%
signal peptide
98%
screening
72%
Escherichia coli
65%
peptide libraries
17%
10
Citations (Scopus)
159
Downloads (Pure)
Optimising host cell physiology and stress avoidance for the production of recombinant human tumour necrosis factor α in
Escherichia coli
Selas Castineiras, T.
,
Williams, S.
,
Hitchcock, A.
,
Cole, J.
,
Smith, D.
&
Overton, T.
,
1 Apr 2018
,
In:
Microbiology.
164
,
p. 440-452
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
human TNF protein
100%
Cell Physiological Phenomena
93%
Recombinant Proteins
71%
Escherichia coli
51%
Tumor Necrosis Factor-alpha
29%
3
Citations (Scopus)
279
Downloads (Pure)