KTP - Cobra Biologics Ltd - Development of innovative screening procedures and high productivity expression and fermentation processes for the production of novel therapeutics proteins in microbial systems

Overton, Tim (Principal Investigator)

Chemical Engineering

Short title	KTP - Cobra Biologics Ltd - Development of innovative screening procedures and high productivity expression and fermentation processes for the production of novel therapeutics proteins in microbial systems
Status	Finished
Effective start/end date	11/02/13 → 10/02/16

Funding

KNOWLEDGE TRANSFER PARTNERSHIPS
COBRA BIOLOGICS LTD

Optimisation of recombinant TNFα production in Escherichia coli using GFP fusions and flow cytometry
Zulkifly, A., Selas Castineiras, T. & Overton, T., 2 Aug 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 12 p., 1171823.
Research output: Contribution to journal › Article › peer-review

Open Access
File
59 Downloads (Pure)
Development of a generic β-lactamase screening system for improved signal peptides for periplasmic targeting of recombinant proteins in Escherichia coli
Selas Castineiras, T., Williams, S., Hitchcock, A., Cole, J., Smith, D. & Overton, T., 3 May 2018, In: Scientific Reports. 8, 6986.
Research output: Contribution to journal › Article › peer-review

Open Access
File
10 Citations (Scopus)

228 Downloads (Pure)
Optimising host cell physiology and stress avoidance for the production of recombinant human tumour necrosis factor α in Escherichia coli
Selas Castineiras, T., Williams, S., Hitchcock, A., Cole, J., Smith, D. & Overton, T., 1 Apr 2018, In: Microbiology. 164, p. 440-452
Research output: Contribution to journal › Article › peer-review

Open Access
File
3 Citations (Scopus)

375 Downloads (Pure)