Investigation of proven vaccine breakthrough by SARS-CoV-2 variants in established UK healthcare worker cohorts: SIREN consortium & PITCH Plus Pathway

Richter, Alex (Principal Investigator)

Short title	Investigation of proven vaccine breakthrough by SARS-CoV-2 variants in established UK healthcare worker cohorts: SIREN consortium & PITCH Plus Pathway
Status	Finished
Effective start/end date	13/08/21 → 10/02/23

Funding

Medical Research Council

4 Article
1 Review article

Dynamic impact of bivalent COVID-19 vaccine boosters on systemic and mucosal antibody and T cell immunity
Kronsteiner, B., Govender, M., Liu, C., Dijokaite-Guraliuc, A., Ali, M., Hill, J., Zewdie, M., Cross, A., Austin, J., Watts, A., Angyal, A., Hornsby, H., Abraham, P., Adele, S., Moulik, S., Harte, J., Hargreaves, A., Jiwa, Y., Selvaraj, M. & Stafford, L. & 25 others, Jamsen, A., Dobson, S. L., Sampaio, S., Halstead, C., Steel, A., Longet, S., Faustini, S. E., Moore, S. C., Mongkolsapaya, J., Wootton, D. G., Thaventhiran, J. E. D., Hopkins, S., Hall, V., Jeffery, K., Barnes, E., Duncan, C. J. A., Payne, R. P., Richter, A. G., de Silva, T. I., Turtle, L., Screaton, G. R., Klenerman, P., Carroll, M., Dunachie, S. J. & PITCH Consortium, 27 Nov 2025, (E-pub ahead of print) In: Scientific Reports.
Research output: Contribution to journal › Article › peer-review

Open Access
File
COVID-19 vaccines are effective at preventing symptomatic and severe infection among healthcare workers: A clinical review
Galgut, O., Ashford, F., Deeks, A., Ghataure, A., Islam, M., Sambhi, T., Ker, Y. W., Duncan, C. J. A., de Silva, T. I., Hopkins, S., Hall, V., Klenerman, P., Dunachie, S. & Richter, A., Oct 2024, In: Vaccine: X. 20, 10 p., 100546.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
97 Downloads (Pure)
CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study
Crick COVID Immunity Pipeline, PITCH Consortium, Neale, I., Ali, M., Kronsteiner, B., Longet, S., Abraham, P., Deeks, A. S., Brown, A., Moore, S. C., Stafford, L., Dobson, S. L., Plowright, M., Newman, T. A. H., Wu, M. Y., Carr, E. J., Beale, R., Otter, A. D., Hopkins, S. & Hall, V. & 11 others, Tomic, A., Payne, R. P., Barnes, E., Richter, A., Duncan, C. J. A., Turtle, L., de Silva, T. I., Carroll, M., Lambe, T., Klenerman, P. & Dunachie, S., 31 Oct 2023, In: mBio. 14, 5, 22 p., e0121223.
Research output: Contribution to journal › Article › peer-review

Open Access
File
21 Downloads (Pure)

Investigation of proven vaccine breakthrough by SARS-CoV-2 variants in established UK healthcare worker cohorts: SIREN consortium & PITCH Plus Pathway

Project Details

Funding

Fingerprint

Dynamic impact of bivalent COVID-19 vaccine boosters on systemic and mucosal antibody and T cell immunity

COVID-19 vaccines are effective at preventing symptomatic and severe infection among healthcare workers: A clinical review

CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study

Investigation of proven vaccine breakthrough by SARS-CoV-2 variants in established UK healthcare worker cohorts: SIREN consortium & PITCH Plus Pathway

Project Details

Funding

Fingerprint

Research output

Dynamic impact of bivalent COVID-19 vaccine boosters on systemic and mucosal antibody and T cell immunity

COVID-19 vaccines are effective at preventing symptomatic and severe infection among healthcare workers: A clinical review

CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study