Investigating the metabolic and epigenetic basis of the immediate and persistent state of systemic immune paresis that occurs following major trauma

Hazeldine, Jon (Principal Investigator)

Inflammation and Ageing

Short title	Investigating the metabolic and epigenetic basis of the immediate and persistent state of systemic immune paresis that occurs following major trauma
Status	Active
Effective start/end date	1/03/23 → 29/02/28

Funding

Medical Research Council

8 Article

Major Traumatic and Severe Thermal Injuries Lead to Immediate and Persistent Elevations in Circulating Concentrations of Resistin That Are Associated with Poor Clinical Outcomes and Impaired Innate Immune Responses
Horner, E., McGee, K. C., Tullie, S., Naumann, D. N., Acharjee, A., Lissillour, T., Asiri, A., Ng, J. M. S., Sullivan, J., Sardeli, A. V., Harrison, P., Belli, A., Moiemen, N. S., Lord, J. M. & Hazeldine, J., 16 Mar 2026, In: Biomolecules. 16, 3, 25 p., 443.
Research output: Contribution to journal › Article › peer-review

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Accelerated epigenetic ageing after burn injury
Sullivan, J., Nicholson, T., Hazeldine, J., Moiemen, N. & Lord, J. M., 16 Jan 2025, (E-pub ahead of print) In: GeroScience.
Research output: Contribution to journal › Article › peer-review

Open Access
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Day One Cell-Free DNA Levels as an Objective Prognostic Marker of Mortality in Major Burns Patients
Tullie, S., Asiri, A., Acharjee, A., Moiemen, N. S., Lord, J. M., Harrison, P. & Hazeldine, J., 1 Jun 2025, In: Cells. 14, 11, 19 p., 821.
Research output: Contribution to journal › Article › peer-review

Open Access
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