Investigating the mechanisms of succinate mediated Nav1.5 dysfunction in human cardiac cell models Sub-project of 21502

Gehmlich, Katja (Co-Investigator)
Holmes, Andy (Principal Investigator)

Short title	Investigating the mechanisms of succinate mediated Nav1.5 dysfunction in human cardiac cell models Sub-project of 21502
Status	Finished
Effective start/end date	1/05/22 → 30/04/23

Funding

British Heart Foundation

Mechanosensitive biochemical imprinting of the talin interaction with DLC1 regulates RhoA activity and cardiomyocyte remodeling
Marhuenda, E., Xanthis, I., O. Smith, P., Prakash , A., Kallem, T., Pandey, P., Wilson, D. G. S., Azad, A., Richter, M., Pavlovic, D., Gehmlich, K., Faggian, G., Swiatlowska, P., Ehler, E., Levitt, J., Poland, S. P., Ameer-Beg, S., Goult , B. T. & Iskratsch, T., 5 Sept 2025, In: Science Advances. 11, 36, 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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Should young athletes be screened for cardiomyopathies to reduce the burden of sudden cardiac death in athletes?
McColgan, G., Villarroel, M. & Gehmlich, K., 23 Jun 2023, In: Biophysical Reviews. 15, 3, p. 321-327 7 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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33 Downloads (Pure)