Investigating lactate as an inflammatory early signal in ectopic lymphoid neogenesis and its translational impact in patients with autoimmune diseases

Mauro, Claudio (Principal Investigator)

Inflammation and Ageing

Short title	Investigating lactate as an inflammatory early signal in ectopic lymphoid neogenesis and its translational impact in patients with autoimmune diseases
Status	Finished
Effective start/end date	1/03/20 → 28/02/23

Funding

Medical Research Council

4 Review article
3 Article

DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation
Niven, J., Kucuk, S., Gope, A., Certo, M., Cassidy, F. C., Arana Echarri, A., Ali, S., Ladoukakis, E., Vidali, S., Macchi, C., Amir, S. S., Bergin, R., Davies, S., Perkin, O. J., Smith, J., Cucchi, D., Heneghan, H., Wijesinghe, S., Jenkins, B. J. & Baig, S. & 20 others, Mahony, C., Chidomere, C., Sarkar, S., Nicolaou, A., Caamaño, J., Croft, A., Davies, E., Thompson, D., O’Shea, D., Jones, S. W., Duggal, N. A., Ruscica, M., Makarova, M., Jones, N., Da Silva Xavier, G., Geberhiwot, T., Turner, J. E., Hogan, A. E., Nedjai, B. & Mauro, C., 27 Apr 2026, (E-pub ahead of print) In: EMBO Reports. 27 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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17 Downloads (Pure)
A novel approach to enhance glioblastoma multiforme treatment efficacy: non-coding RNA targeted therapy and adjuvant approaches
Liu, M., Wang, Y., Chen, X., Zeng, Y., Huang, W., Yang, J., Dai, H., Cheng, L., Mauro, C. & Cheung, K. C. P., 21 Jun 2025, In: Clinical epigenetics. 17, 1, 17 p., 108.
Research output: Contribution to journal › Review article › peer-review

Open Access
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14 Downloads (Pure)
Lactate: A key regulator of the immune response
Llibre, A., Kucuk, S., Gope, A., Certo, M. & Mauro, C., 11 Mar 2025, In: Immunity. 58, 3, p. 535-554 20 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
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171 Downloads (Pure)