Interrogating nicotinamide riboside kinase activity as a key determinant of CD4+ T cell metabolism, fate and function

Lavery, Gareth (Co-Investigator)
Dimeloe, Sarah (Principal Investigator)

Short title	Interrogating nicotinamide riboside kinase activity as a key determinant of CD4+ T cell metabolism, fate and function
Status	Finished
Effective start/end date	1/08/21 → 30/09/24

Funding

Medical Research Council

1 Article

TNF-α signals through ITK-Akt-mTOR to drive CD4⁺ T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis
Bishop, E. L., Gudgeon, N., Fulton-Ward, T., Stavrou, V., Roberts, J., Boufersaoui, A., Tennant, D. A., Hewison, M., Raza, K. & Dimeloe, S., 23 Apr 2024, In: Science signaling. 17, 833, eadg5678.
Research output: Contribution to journal › Article › peer-review

Open Access
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