Immunity to Gamma-Herpesviruses

Research output

Research output per year 2007 2007 2008 2009 2011 2012

• 18 Article

Research output per year

Research output per year

Search results

• 2012

  Suppression of antigen-specific T cell responses by the Kaposi's sarcoma-associated herpesvirus viral OX2 protein and its cellular orthologue, CD200

  Misstear, K., Chanas, S. A., Rezaee, S. A. R., Colman, R., Quinn, L. L., Long, H. M., Goodyear, O., Lord, J. M., Hislop, A. D. & Blackbourn, D. J., 2012, In: Journal of virology. 86, 11, p. 6246-57 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Human gammaherpesvirus 8 100%
  • Human Herpesvirus 8 73%
  • viral proteins 65%
  • Viral Proteins 60%
  • T-lymphocytes 52%
  30 Citations (Scopus)

• T-cell immunity to Kaposi's sarcoma-associated herpesvirus: recognition of primary effusion lymphoma with LANA-specific CD4+ T cells.

  Sabbah, S., Jagne, YJ., Zuo, J., de Silva, T., Ahasan, MM., Brander, C., Rowland-Jones, S., Flanagan, KL. & Hislop, A., 10 Jan 2012, In: Blood. 119, 9, p. 2083-2092 10 p.

  Research output: Contribution to journal › Article

  • Primary Effusion Lymphoma 100%
  • Human Herpesvirus 8 85%
  • Immunity 54%
  • T-Lymphocytes 41%
  • Donor 30%
  22 Citations (Scopus)
• 2011

  EBV Protein BNLF2a Exploits Host Tail-Anchored Protein Integration Machinery To Inhibit TAP

  Horst, D., Favaloro, V., Vilardi, F., van Leeuwen, HC., Garstka, MA., Hislop, A., Rabu, C., Kremmer, E., Rickinson, A., High, S., Dobberstein, B., Ressing, ME. & Wiertz, EJHJ., 1 Mar 2011, In: Journal of Immunology. 186, 6, p. 3594-3605 12 p.

  Research output: Contribution to journal › Article

  • human herpesvirus 4 BNLF21 protein 100%
  • Human Herpesvirus 4 23%
  • Membranes 23%
  • Endoplasmic Reticulum 22%
  • Immune Evasion 19%
  28 Citations (Scopus)

• Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP

  Palendira, U., Low, C., Chan, A., Hislop, A., Ho, E., Deenick, E., Cook, MC., Riminton, DS., Choo, S., Loh, R., Alvaro, F., Booth, C., Gaspar, HB., Moretta, A., Khanna, R., Rickinson, A. & Tangye, SG., 1 Nov 2011, In: PLoS Biology. 9, 11, p. e1001187

  Research output: Contribution to journal › Article

  Open Access

  • Lymphoproliferative Disorders 100%
  • Human Herpesvirus 4 84%
  • pathogenesis 77%
  • Mutation 71%
  • Epstein-Barr Virus Infections 68%
  87 Citations (Scopus)

• The Epstein-Barr virus-encoded BILF1 protein modulates immune recognition of endogenously processed antigen by targeting MHC class I molecules trafficking on both the exocytic and endocytic pathways.

  Zuo, J., Quinn, L., Tamblyn, J., Thomas, W., Feederle, R., Delecluse, HJ., Hislop, A. & Rowe, M., 1 Feb 2011, In: Journal of virology. 85, 4, p. 1604-1614 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Epstein-Barr virus BILF1 protein 100%
  • Human gammaherpesvirus 4 54%
  • Histocompatibility Antigens Class I 48%
  • Human Herpesvirus 4 40%
  • antigen presentation 30%
  50 Citations (Scopus)
• 2010

  Impaired Epstein-Barr virus-specific CD8+ T cell function in X-linked lymphoproliferative disease is restricted to SLAM family positive B cell targets.

  Hislop, A., Palendira, U., Leese, A., Arkwright, PD., Rohrlich, PS., Tangye, SG., Gaspar, HB., Lankester, AC., Moretta, A. & Rickinson, A., 19 Jul 2010, In: Blood. 116, 17, p. 3249-3257 9 p.

  Research output: Contribution to journal › Article

  • Signaling Lymphocytic Activation Molecule Family 100%
  • Lymphoproliferative Disorders 66%
  • Human Herpesvirus 4 56%
  • B-Lymphocytes 43%
  • T-Lymphocytes 35%
  82 Citations (Scopus)
• 2009

  An HLA-A2-Restricted T-Cell Epitope Mapped to the BNLF2a Immune Evasion Protein of Epstein-Barr Virus That Inhibits TAP

  Bell, MJ., Abbott, R., Croft, N., Hislop, A. & Burrows, SR., 1 Mar 2009, In: Journal of virology. 83, 6, p. 2783-2788 6 p.

  Research output: Contribution to journal › Article

  • immune evasion 100%
  • HLA-A2 Antigen 91%
  • Human gammaherpesvirus 4 90%
  • Immune Evasion 85%
  • T-Lymphocyte Epitopes 81%
  10 Citations (Scopus)

• Specific Targeting of the EBV Lytic Phase Protein BNLF2a to the Transporter Associated with Antigen Processing Results in Impairment of HLA Class I-Restricted Antigen Presentation

  Horst, D., van Leeuwen, D., Croft, N., Garstka, MA., Hislop, A., Kremmer, E., Rickinson, A., Wiertz, EJHJ. & Ressing, ME., 1 Feb 2009, In: Journal of Immunology. 182, 4, p. 2313-2324 12 p.

  Research output: Contribution to journal › Article

  • Histocompatibility Antigens Class I 100%
  • Antigen Presentation 92%
  • HLA Antigens 86%
  • Human Herpesvirus 4 83%
  • Endoplasmic Reticulum 48%
  73 Citations (Scopus)

• Stage-Specific Inhibition of MHC Class I Presentation by the Epstein-Barr Virus BNLF2a Protein during Virus Lytic Cycle.

  Croft, N., Shannon-Lowe, C., Bell, A., Horst, D., Kremmer, E., Ressing, ME., Wiertz, EJ., Middeldorp, JM., Rowe, M., Rickinson, A. & Hislop, A., 1 Jun 2009, In: PLoS pathogens. 5, 6, p. e1000490

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Human gammaherpesvirus 4 100%
  • Human Herpesvirus 4 74%
  • Viruses 49%
  • viruses 48%
  • T-lymphocytes 34%
  62 Citations (Scopus)

  148 Downloads (Pure)

• The effects of acute malaria on Epstein-Barr virus (EBV) load and EBV-specific T cell immunity in Gambian children.

  Njie, R., Bell, A., Jia, H., Croom-Carter, D., Chaganti, S., Hislop, A., Whittle, H. & Rickinson, A., 1 Jan 2009, In: The Journal of Infectious Diseases. 199, 1, p. 31-8 8 p.

  Research output: Contribution to journal › Article

  • Acute malaria 100%
  • Human Herpesvirus 4 65%
  • Immunity 53%
  • T-Lymphocytes 40%
  • Child 28%
  63 Citations (Scopus)

• Upregulation of Interleukin 7 Receptor Alpha and Programmed Death 1 Marks an Epitope-Specific CD8(+) T-Cell Response That Disappears following Primary Epstein-Barr Virus Infection

  Sauce, D., Larsen, M., Abbott, R., Hislop, A., Leese, A., Khan, N., Papagno, L., Freeman, GJ. & Rickinson, A., 1 Sept 2009, In: Journal of virology. 83, 18, p. 9068-9078 11 p.

  Research output: Contribution to journal › Article

  • glycyl-leucyl-cysteinyl-threonyl-leucyl-valyl-alanyl-methionyl-leucine 100%
  • interleukin-7 72%
  • Interleukin-7 Receptors 68%
  • Human gammaherpesvirus 4 59%
  • Infectious Mononucleosis 58%
  15 Citations (Scopus)
• 2008

  CD8+ T cell immunity to Epstein-Barr virus and Kaposi's sarcoma-associated herpes virus.

  Hislop, A. & Sabbah, S., 1 Dec 2008, In: Seminars in Cancer Biology. 18, 6, p. 416-22 7 p.

  Research output: Contribution to journal › Article

  • Satellite Viruses 100%
  • Human Herpesvirus 8 94%
  • Kaposi's Sarcoma 86%
  • Human Herpesvirus 4 73%
  • Immunity 60%
  16 Citations (Scopus)

• Epstein-Barr virus persistence in the absence of conventional memory B cells: IgM+IgD+CD27+ B cells harbor the virus in X-linked lymphoproliferative disease patients

  Chaganti, S., Ma, CS., Bell, A., Croom-Carter, D., Hislop, A., Tangye, SG. & Rickinson, A., 1 Aug 2008, In: Blood. 112, 3, p. 672-9 8 p.

  Research output: Contribution to journal › Article

  • Immunoglobulin D 100%
  • Lymphoproliferative Disorders 87%
  • Human Herpesvirus 4 73%
  • Immunoglobulin M 65%
  • Marker 64%
  33 Citations (Scopus)

• Selective accumulation of virus-specific CD8+ T cells with unique homing phenotype within the human bone marrow

  Palendira, U., Chinn, R., Raza, W., Piper, K., Pratt, G., Machado, L., Bell, A., Khan, N., Hislop, A., Steyn, R., Rickinson, A., Buckley, C. & Moss, P., 15 Oct 2008, In: Blood. 112, 8, p. 3293-302 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Epitope 100%
  • Partition 97%
  • Antigen 82%
  • Bone Marrow 71%
  • Viruses 65%
  62 Citations (Scopus)

  6 Downloads (Pure)

• Synthesis andex vivo profiling of chemically modified cytomegalovirus CMVpp65 epitopes

  Jones, MA., Notta, JK., Cobbold, M., Palendira, M., Hislop, A., Wilkie, J. & Snaith, J., 1 Mar 2008, In: Journal of Peptide Science. 14, 3, p. 313-320 8 p.

  Research output: Contribution to journal › Article

  • Epitope 100%
  • Cytomegalovirus 97%
  • Epitopes 84%
  • HLA-A*02:01 antigen 74%
  • Peptides 62%
  3 Citations (Scopus)
• 2007

  A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates

  Hislop, A., Ressing, ME., van Leeuwen, D., Pudney, V., Horst, D., Koppers-Lalic, D., Croft, N., Neefjes, JJ., Rickinson, A. & Wiertz, EJHJ., 6 Aug 2007, In: The Journal of Experimental Medicine. 204, 8, p. 1863-73 11 p.

  Research output: Contribution to journal › Article

  • Immune Evasion 100%
  • Human Herpesvirus 4 78%
  • Primates 73%
  • Herpesviridae 73%
  • HLA Antigens 65%
  127 Citations (Scopus)

• Cellular responses to viral infection in humans: lessons from Epstein-Barr virus

  Hislop, A., Taylor, G., Sauce, D. & Rickinson, A., 1 Jan 2007, In: Annual review of immunology. 25, p. 587-617 31 p.

  Research output: Contribution to journal › Article

  • Human Herpesvirus 4 100%
  • Infectious Mononucleosis 88%
  • Virus Diseases 74%
  • Cellular Immunity 64%
  • Interleukin-15 42%
  521 Citations (Scopus)

• IL7Ra versus CCR7 and CD45 as markers of virus specific CD8+ T cell differentiation: Contrasting pictures in blood and tonsillar lymphoid tissue

  Sauce, D., Larsen, M., Leese, A., Millar, D., Khan, N., Hislop, A. & Rickinson, A., 15 Jan 2007, In: The Journal of Infectious Diseases. 195, p. 268-278 11 p.

  Research output: Contribution to journal › Article

  • Lymphoid Tissue 100%
  • Human Herpesvirus 4 92%
  • Cell Differentiation 75%
  • Viruses 61%
  • Cytomegalovirus 61%
  20 Citations (Scopus)