Identification of DNA elements that maintain epigenetic memory in T Cells

Cockerill, Peter (Principal Investigator)
Bonifer, Conny (Co-Investigator)

Cancer and Genomic Sciences

3 Article
3 Review article

6 results

2017
Chromatin priming elements establish immunological memory in T cells without activating transcription: T cell memory is maintained by DNA elements which stably prime inducible genes without activating steady state transcription
Bevington, S. L., Cauchy, P. & Cockerill, P. N., 1 Feb 2017, In: BioEssays. 39, 2, 1600184.
Research output: Contribution to journal › Review article › peer-review

Open Access
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16 Citations (Scopus)

136 Downloads (Pure)
Chromatin priming of genes in development: concepts, mechanisms and consequences
Bonifer, C. & Cockerill, P., May 2017, In: Experimental Hematology. 49, p. 1-8
Research output: Contribution to journal › Review article › peer-review

Open Access
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14 Citations (Scopus)

155 Downloads (Pure)
Integration of kinase and calcium signaling at the level of chromatin underlies inducible gene activation in T cells
Brignall, R., Cauchy, P., Bevington, S., Gorman, B., Pisco, A. O., Bagnall, J., Boddington, C., Rowe, W., England, H., Rich, K., Schmidt, L., Dyer, N. P., Travis, M. A., Ott, S., Jackson, D. A., Cockerill, P. & Paszek, P., 15 Oct 2017, In: Journal of Immunology. 199, 8, p. 2652-2667 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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17 Citations (Scopus)

203 Downloads (Pure)
T cell receptor and cytokine signaling can function at different stages to establish and maintain transcriptional memory and enable T helper cell differentiation
Bevington, S. L., Cauchy, P., Withers, D. R., Lane, P. J. L. & Cockerill, P. N., 3 Mar 2017, In: Frontiers in immunology. 8, 16 p., 204.
Research output: Contribution to journal › Review article › peer-review

Open Access
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12 Citations (Scopus)

172 Downloads (Pure)
2016
Inducible chromatin priming is associated with the establishment of immunological memory in T cells
Bevington, S., Cauchy, P., Piper, J., Bertrand, E., Lalli, N., Jarvis, R., Gilding, N., Ott, S., Bonifer, C. & Cockerill, P., Mar 2016, In: The EMBO journal. 35, 5, p. 515-535 21 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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44 Citations (Scopus)

157 Downloads (Pure)
2012
The Inducible Tissue-Specific Expression of the Human IL-3/GM-CSF Locus Is Controlled by a Complex Array of Developmentally Regulated Enhancers
Baxter, E. W., Mirabella, F., Bowers, S. R., James, S. R., Bonavita, A-M., Bertrand, E., Strogantsev, R., Hawwari, A., Bert, A. G., Gonzalez de Arce, A., West, A. G., Bonifer, C. & Cockerill, P. N., 1 Nov 2012, In: Journal of Immunology. 189, 9, p. 4459-69 11 p.
Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus)

Identification of DNA elements that maintain epigenetic memory in T Cells

Research output

Search results

Chromatin priming elements establish immunological memory in T cells without activating transcription: T cell memory is maintained by DNA elements which stably prime inducible genes without activating steady state transcription

Chromatin priming of genes in development: concepts, mechanisms and consequences

Integration of kinase and calcium signaling at the level of chromatin underlies inducible gene activation in T cells

T cell receptor and cytokine signaling can function at different stages to establish and maintain transcriptional memory and enable T helper cell differentiation

Inducible chromatin priming is associated with the establishment of immunological memory in T cells

The Inducible Tissue-Specific Expression of the Human IL-3/GM-CSF Locus Is Controlled by a Complex Array of Developmentally Regulated Enhancers