Epigenetic mechanisms that maintain immunological memory in CD4 T cells

Lane, Peter (Co-Investigator)
Withers, David (Co-Investigator)
Cockerill, Peter (Principal Investigator)

Short title	Epigenetic mechanisms that maintain immunological memory in CD4 T cells
Status	Finished
Effective start/end date	19/09/16 → 22/10/20

Funding

Medical Research Council

3 Article

Stable epigenetic programming of effector and central memory CD4 T cells occurs within 7 days of antigen exposure in vivo
Bevington, S., Fiancette, R., Gajdasik, D., Keane, P., Soley, J., Willis, C., Coleman, D., Withers, D. & Cockerill, P., 24 May 2021, In: Frontiers in immunology. 12, 19 p., 642807.
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Chromatin priming renders T cell tolerance-associated genes sensitive to activation below the signaling threshold for immune response genes
Bevington, S. L., Ng, S. T. H., Britton, G. J., Keane, P., Wraith, D. C. & Cockerill, P. N., 9 Jun 2020, In: Cell Reports. 31, 10, 25 p., 107748.
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5 Citations (Scopus)

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IL-2/IL-7-inducible factors pioneer the path to T cell differentiation in advance of lineage-defining factors
Bevington, S. L., Keane, P., Soley, J. K., Tauch, S., Gajdasik, D. W., Fiancette, R., Matei-Rascu, V., Willis, C. M., Withers, D. R. & Cockerill, P. N., 15 Sept 2020, (E-pub ahead of print) In: The EMBO journal. 39, 22, e105220.
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4 Citations (Scopus)

362 Downloads (Pure)