Defining the Metabolic Phenotype of Glial Tumours

Tennant, Daniel (Principal Investigator)
Cruickshank, Garth (Co-Investigator)

Short title	Defining the Metabolic Phenotype of Glial Tumours
Status	Finished
Effective start/end date	1/10/12 → 30/09/16

Funding

ASTRA ZENECA UK LIMITED

2 Article

Oncogenic IDH1 mutations promote enhanced proline synthesis through PYCR1 to support the maintenance of mitochondrial redox homeostasis
Hollinshead, K., Munford, H., Eales, K., Bardella, C., Li, C., Escribano Gonzalez, C., Thakker, A., Nonnenmacher, Y., Kluckova, K., Jeeves, M., Murren, R., Cuozzo, F., Ye, D., Laurenti, G., Zhu, W., Hiller, K., Hodson, D., Hua, W., Tomlinson, I. & Ludwig, C. & 2 others, Mao, Y. & Tennant, D., 20 Mar 2018, In: Cell Reports. 22, 12, p. 3107–3114 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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22 Citations (Scopus)

300 Downloads (Pure)
Hypoxia and metabolic adaptation of cancer cells
Eales, K., Hollinshead, K. & Tennant, D., 25 Jan 2016, In: Oncogenesis. 5, e190.
Research output: Contribution to journal › Article › peer-review

Open Access
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289 Downloads (Pure)