Changes in Mitochondrial Function in Glioma and the Role of Mitochondrial Metabolism in Therapy Resistance

Tennant, Daniel (Principal Investigator)
Cruickshank, Garth (Co-Investigator)
Cooper, Helen (Co-Investigator)
Guenther, Ulrich (Co-Investigator)
Viant, Mark (Co-Investigator)

Short title	Changes in Mitochondrial Function in Glioma and the Role of Mitochondrial Metabolism in Therapy Resistance
Status	Finished
Effective start/end date	1/10/13 → 30/09/16

Funding

SAMANTHA DICKSON (BRAIN TUMOUR) RESEARCH TRUST
THE BRAIN TUMOUR CHARITY

1 Article

Oncogenic IDH1 mutations promote enhanced proline synthesis through PYCR1 to support the maintenance of mitochondrial redox homeostasis
Hollinshead, K., Munford, H., Eales, K., Bardella, C., Li, C., Escribano Gonzalez, C., Thakker, A., Nonnenmacher, Y., Kluckova, K., Jeeves, M., Murren, R., Cuozzo, F., Ye, D., Laurenti, G., Zhu, W., Hiller, K., Hodson, D., Hua, W., Tomlinson, I. & Ludwig, C. & 2 others, Mao, Y. & Tennant, D., 20 Mar 2018, In: Cell Reports. 22, 12, p. 3107–3114 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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22 Citations (Scopus)

277 Downloads (Pure)