Can combined cellular and 11beta-hydroxysteroid dehydrogenase-1 gene therapy attenuate inflammation in acute respiratory distress syndrome

Mahida, Rahul (Principal Investigator)
Thickett, David (Co-Investigator)

Inflammation and Ageing

5 Article

5 results

2023
Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS
Mahida, R. Y., Lax, S., Bassford, C. R., Scott, A., Parekh, D., Hardy, R. S., Naidu, B., Matthay, M. A., Stewart, P. M., Cooper, M. C., Perkins, G. D. & Thickett, D. R., 27 Apr 2023, In: Frontiers in immunology. 14, 14 p., 1159831.
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2022
CD14-positive extracellular vesicles in bronchoalveolar lavage fluid as a new biomarker of acute respiratory distress syndrome
Mahida, R. Y., Price, J., Lugg, S. T., Li, H., Parekh, D., Scott, A., Harrison, P., Matthay, M. A. & Thickett, D. R., 6 Apr 2022, In: American journal of physiology. Lung cellular and molecular physiology. 322, 4, p. L617-L624
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2021

Acute respiratory distress syndrome is associated with impaired alveolar macrophage efferocytosis
Mahida, R. Y., Scott, A., Parekh, D., Lugg, S. T., Hardy, R. S., Lavery, G. G., Matthay, M. A., Naidu, B., Perkins, G. D. & Thickett, D. R., 9 Sept 2021, In: The European respiratory journal. 58, 3, 2100829.
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Assessment of Alveolar Macrophage Dysfunction Using an in vitro Model of Acute Respiratory Distress Syndrome
Mahida, R. Y., Scott, A., Parekh, D., Lugg, S. T., Belchamber, K. B. R., Hardy, R. S., Matthay, M. A., Naidu, B. & Thickett, D. R., 29 Sept 2021, In: Frontiers in Medicine. 8, 737859.
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2020
Characterisation and outcomes of ARDS secondary to pneumonia in patients with and without SARS-CoV-2: a single-centre experience
Mahida, R. Y., Chotalia, M., Alderman, J., Patel, C., Hayden, A., Desai, R., Beesley, E., Crowley, L. E., Soltan, M., Bangash, M., Parekh, D., Patel, J. & Thickett, D. R., 30 Nov 2020, In: BMJ Open Respiratory Research. 7, 1, e000731.
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Can combined cellular and 11beta-hydroxysteroid dehydrogenase-1 gene therapy attenuate inflammation in acute respiratory distress syndrome

Research output

Search results

Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS

CD14-positive extracellular vesicles in bronchoalveolar lavage fluid as a new biomarker of acute respiratory distress syndrome

Acute respiratory distress syndrome is associated with impaired alveolar macrophage efferocytosis

Assessment of Alveolar Macrophage Dysfunction Using an in vitro Model of Acute Respiratory Distress Syndrome

Characterisation and outcomes of ARDS secondary to pneumonia in patients with and without SARS-CoV-2: a single-centre experience