Can combined cellular and 11beta-hydroxysteroid dehydrogenase-1 gene therapy attenuate inflammation in acute respiratory distress syndrome

Mahida, Rahul (Principal Investigator)
Thickett, David (Co-Investigator)

Inflammation and Ageing

Short title	Can combined cellular and 11beta-hydroxysteroid dehydrogenase-1 gene therapy attenuate inflammation in acute respiratory distress syndrome
Status	Finished
Effective start/end date	3/08/16 → 2/11/19

Funding

Medical Research Council

6 Article

11β hydroxysteroid dehydrogenase type 1 transgenic mesenchymal stem cells attenuate inflammation in models of sepsis
Mahida, R. Y., Yuan, Z., Kolluri, K. K., Scott, A., Parekh, D., Hardy, R. S., Matthay, M. A., Perkins, G. D., Janes, S. M. & Thickett, D. R., 5 Jul 2024, In: Frontiers in Bioengineering and Biotechnology. 12, 15 p., 1422761.
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Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS
Mahida, R. Y., Lax, S., Bassford, C. R., Scott, A., Parekh, D., Hardy, R. S., Naidu, B., Matthay, M. A., Stewart, P. M., Cooper, M. C., Perkins, G. D. & Thickett, D. R., 27 Apr 2023, In: Frontiers in immunology. 14, 14 p., 1159831.
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CD14-positive extracellular vesicles in bronchoalveolar lavage fluid as a new biomarker of acute respiratory distress syndrome
Mahida, R. Y., Price, J., Lugg, S. T., Li, H., Parekh, D., Scott, A., Harrison, P., Matthay, M. A. & Thickett, D. R., 6 Apr 2022, In: American journal of physiology. Lung cellular and molecular physiology. 322, 4, p. L617-L624 8 p.
Research output: Contribution to journal › Article › peer-review

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