Biosynthesis of polyketide antibiotic mupirocin by Pseudomonas fluorescens

Project Details

Short titleBiosynthesis of polyketide antibiotic mupirocin by Pseudomonas fluorescens
StatusFinished
Effective start/end date1/06/0730/01/11

Funding

  • BIOTECHNOLOGY & BIOLOGICAL SCIENCES

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
  • Minimum Information about a Biosynthetic Gene cluster

    Medema, M. H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J. B., Blin, K., De Bruijn, I., Chooi, Y. H., Claesen, J., Coates, R. C., Cruz-Morales, P., Duddela, S., Düsterhus, S., Edwards, D. J., Fewer, D. P., Garg, N., Geiger, C., Gomez-Escribano, J. P., Greule, A., Hadjithomas, M. & 135 others, Haines, A. S., Helfrich, E. J. N., Hillwig, M. L., Ishida, K., Jones, A. C., Jones, C. S., Jungmann, K., Kegler, C., Kim, H. U., Kötter, P., Krug, D., Masschelein, J., Melnik, A. V., Mantovani, S. M., Monroe, E. A., Moore, M., Moss, N., Nützmann, H. W., Pan, G., Pati, A., Petras, D., Reen, F. J., Rosconi, F., Rui, Z., Tian, Z., Tobias, N. J., Tsunematsu, Y., Wiemann, P., Wyckoff, E., Yan, X., Yim, G., Yu, F., Xie, Y., Aigle, B., Apel, A. K., Balibar, C. J., Balskus, E. P., Barona-Gómez, F., Bechthold, A., Bode, H. B., Borriss, R., Brady, S. F., Brakhage, A. A., Caffrey, P., Cheng, Y. Q., Clardy, J., Cox, R. J., De Mot, R., Donadio, S., Donia, M. S., Van Der Donk, W. A., Dorrestein, P. C., Doyle, S., Driessen, A. J. M., Ehling-Schulz, M., Entian, K. D., Fischbach, M. A., Gerwick, L., Gerwick, W. H., Gross, H., Gust, B., Hertweck, C., Höfte, M., Jensen, S. E., Ju, J., Katz, L., Kaysser, L., Klassen, J. L., Keller, N. P., Kormanec, J., Kuipers, O. P., Kuzuyama, T., Kyrpides, N. C., Kwon, H. J., Lautru, S., Lavigne, R., Lee, C. Y., Linquan, B., Liu, X., Liu, W., Luzhetskyy, A., Mahmud, T., Mast, Y., Méndez, C., Metsä-Ketelä, M., Micklefield, J., Mitchell, D. A., Moore, B. S., Moreira, L. M., Müller, R., Neilan, B. A., Nett, M., Nielsen, J., O'Gara, F., Oikawa, H., Osbourn, A., Osburne, M. S., Ostash, B., Payne, S. M., Pernodet, J. L., Petricek, M., Piel, J., Ploux, O., Raaijmakers, J. M., Salas, J. A., Schmitt, E. K., Scott, B., Seipke, R. F., Shen, B., Sherman, D. H., Sivonen, K., Smanski, M. J., Sosio, M., Stegmann, E., Süssmuth, R. D., Tahlan, K., Thomas, C. M., Tang, Y., Truman, A. W., Viaud, M., Walton, J. D., Walsh, C. T., Weber, T., Van Wezel, G. P., Wilkinson, B., Willey, J. M., Wohlleben, W., Wright, G. D., Ziemert, N., Zhang, C., Zotchev, S. B., Breitling, R., Takano, E., Glöckner, F. O. & Thomas, C., 18 Aug 2015, In: Nature Chemical Biology. 11, 9, p. 625-631 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    387 Citations (Scopus)
    136 Downloads (Pure)
  • Biosynthesis of mupirocin by pseudomonas fluorescens NCIMB 10586 involves parallel pathways

    Gao, S. S., Hothersall, J., Wu, JE., Murphy, A. C., Song, Z., Stephens, E. R., Thomas, C. M., Crump, M. P., Cox, R. J., Simpson, T. J. & Willis, C. L., 9 Apr 2014, In: Journal of the American Chemical Society. 136, 14, p. 5501-5507 7 p.

    Research output: Contribution to journalArticlepeer-review

    20 Citations (Scopus)
  • A Natural Plasmid Uniquely Encodes Two Biosynthetic Pathways Creating a Potent Anti-MRSA Antibiotic.

    Fukuda, D., Haines, A., Song, Z., Murphy, AC., Hothersall, J., Stephens, E., Gurney, R., Cox, RJ., Crosby, J., Willis, CL., Simpson, TJ. & Thomas, C., 1 Jan 2011, In: PLoS ONE. 6, 3, p. e18031

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    45 Citations (Scopus)
    235 Downloads (Pure)