BHF Research Accelerator Award

Research output

Research output per year 2019 2020 2021 2023

• 23 Article
• 2 Review article

Research output per year

Research output per year

Search results

• 2023

  Characterisation of patients referred to a tertiary-level inherited cardiac condition clinic with suspected arrhythmogenic right ventricular cardiomyopathy (ARVC)

  Aljehani, A., Kew, T., Baig, S., Cox, H., Sommerfeld, L. C., Ensam, B., Kalla, M., Steeds, R. P. & Fabritz, L., 12 Jan 2023, In: BMC Cardiovascular Disorders. 23, 1, 14.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Rare Diseases 12%
  • Observational Studies 10%
  • Cohort Studies 8%
  • Penetrance 7%
  43 Downloads (Pure)
• 2022

  Anti-platelet factor 4 immunoglobulin G levels in vaccine-induced immune thrombocytopenia and thrombosis: persistent positivity through 7 months

  Montague, S., Smith, C., Lodwick, C. S., Stoneley, C., Roberts, M., Lowe, G., Lester, W., Watson, S. & Nicolson, P., 4 May 2022, In: Research and Practice in Thrombosis and Haemostasis. 6, 3, 8 p., e12707.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Platelet Factor 4 100%
  • Idiopathic Thrombocytopenic Purpura 86%
  • Thrombosis 56%
  • Immunoglobulin G 55%
  • Vaccines 54%
  88 Downloads (Pure)

• High resolution optical mapping of cardiac electrophysiology in pre-clinical models

  O’Shea, C., Winter, J., Kabir, S. N., O’Reilly, M., Wells, S. P., Baines, O., Sommerfeld, L. C., Correia, J., Lei, M., Kirchhof, P., Holmes, A. P., Fabritz, L., Rajpoot, K. & Pavlovic, D., Dec 2022, In: Scientific Data. 9, 1, 12 p., 135.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cardiac Electrophysiology 100%
  • Calcium 88%
  • Action Potential 86%
  • Mouse 74%
  • High Resolution 72%
  32 Downloads (Pure)

• Interactions Between Atrial Fibrillation and Natriuretic Peptide in Predicting Heart Failure Hospitalization or Cardiovascular Death

  Brady, P. F., Chua, W., Nehaj, F., Connolly, D. L., Khashaba, A., Purmah, Y. J. V., Ul-Qamar, M. J., Thomas, M. R., Varma, C., Schnabel, R. B., Zeller, T., Fabritz, L. & Kirchhof, P. F., 15 Feb 2022, In: Journal of the American Heart Association. 11, 4, e022833.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Atrial Natriuretic Factor 100%
  • Atrial Fibrillation 80%
  • Hospitalization 66%
  • Heart Failure 65%
  • Brain Natriuretic Peptide 54%
  42 Downloads (Pure)

• Smartphone and wearable detected atrial arrhythmias in older adults: results of a fully digital European case finding study

  Fabritz, L., Connolly, D. L., Czarnecki, E., Dudek, D., Guasch, E., Haase, D., Huebner, T., Zlahoda-Huzior, A., Jolly, K., Kirchhof, P., Obergassel, J., Schotten, U., Vettorazzi, E., Winkelmann, S. J., Zapf, A. & Schnabel, R. B., Dec 2022, In: European Heart Journal - Digital Health. 3, 4, p. 610–625 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Smartphone 100%
  • Cardiac Arrhythmias 69%
  • Communications Media 26%
  • Photoplethysmography 24%
  • Computer Security 22%
  38 Downloads (Pure)
• 2021

  Anticoagulation, therapy of concomitant conditions, and early rhythm control therapy: a detailed analysis of treatment patterns in the EAST - AFNET 4 trial

  Metzner, A., Suling, A., Brandes, A., Breithardt, G., Camm, A. J., Crijns, H. J. G. M., Eckardt, L., Elvan, A., Goette, A., Haegeli, L. M., Heidbuchel, H., Kautzner, J., Kuck, K-H., Mont, L., Ng, A. A., Szumowski, L., Themistoclakis, S., van Gelder, I. C., Vardas, P., Wegscheider, K., & 2 othersWillems, S. & Kirchhof, P., 2 Sept 2021, (E-pub ahead of print) In: Europace. euab200.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Atrial Fibrillation 100%
  • Secondary Prevention 87%
  • Electrocardiography 54%
  • Anti-Arrhythmia Agents 51%
  • Therapeutics 29%
  33 Downloads (Pure)

• CLEC-2 Prevents Accumulation and Retention of Inflammatory Macrophages During Murine Peritonitis

  Bourne, J., Beristain Covarrubias, N., Zuidscherwoude, M., Campos, J., Di, Y., Garlick, E., Colicchia, M., Terry, L., Thomas, S., Brill, A., Bayry, J., Watson, S. & Rayes, J., 7 Jun 2021, In: Frontiers in immunology. 12, 693974.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Peritonitis 100%
  • Macrophages 68%
  • Inflammation 57%
  • Blood Platelets 50%
  • Peritoneum 36%
  124 Downloads (Pure)

• Galectin-9 activates platelet ITAM receptors glycoprotein VI and C-type lectin-like receptor-2

  Zhi, Z., Jooss, N. J., Sun, Y., Colicchia, M., Slater, A., Moran, L. A., Cheung, H. Y. F., Di, Y., Rayes, J., Poulter, N. S., Watson, S. P. & Iqbal, A. J., 22 Dec 2021, (E-pub ahead of print) In: Journal of thrombosis and haemostasis : JTH. 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Galectins 100%
  • C-Type Lectins 97%
  • Glycoproteins 61%
  • Blood Platelets 56%
  • P-Selectin 17%
  46 Downloads (Pure)

• Impact of Right Ventricular Dysfunction on Mortality in Patients Hospitalized With COVID-19, According to Race

  Moody, W. E., Mahmoud-Elsayed, H. M., Senior, J., Gul, U., Khan-Kheil, A. M., Horne, S., Banerjee, A., Bradlow, W. M., Huggett, R., Hothi, S. S., Shahid, M. & Steeds, R. P., Jan 2021, In: CJC open. 3, 1, p. 91-100 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Right Ventricular Dysfunction 100%
  • Coronavirus 94%
  • Echocardiography 42%
  • Mortality 38%
  • Right Ventricular Function 31%
  98 Downloads (Pure)

• Improving the diagnosis of heart failure in patients with atrial fibrillation

  Bunting, K., Gill, S., Sitch, A., Mehta, S., O'Connor, K., Lip, G., Kirchhof, P., Strauss, V. Y., Rahimi, K., Camm, A. J., Stanbury, M., Griffith, M., Townend, J., Gkoutos, G., Karwath, A., Steeds, R. & Kotecha, D., 12 May 2021, In: Heart. 107, 11, p. 902-908 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Atrial Fibrillation 100%
  • Heart Failure 82%
  • Stroke Volume 61%
  • Natriuretic Peptides 55%
  • Echocardiography 18%
  2 Citations (Scopus)

  141 Downloads (Pure)

• Lymphatic blood filling in CLEC-2-deficient mouse models

  Haining, E., Lowe, K., Wichaiyo, S., Kataru, R. P., Nagy, Z., Kavanagh, D., Lax, S., Di, Y., Nieswandt, B., Ho-Tin-Noé, B., Mehrara, B. J., Senis, Y., Rayes, J. & Watson, S., 3 Apr 2021, In: Platelets. 32, 3, p. 352-367 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • C-Type Lectins 100%
  • Lymphatic Vessels 17%
  • Vascular Remodeling 17%
  • Blood Platelets 11%
  • Lymphatic System 9%
  1 Citation (Scopus)

  222 Downloads (Pure)

• Mobile apps to improve medication adherence in cardiovascular disease: systematic review and meta-analysis

  Al-Arkee, S., Mason, J., Lane, D., Fabritz, L., Chua, W. W. L., Haque, S. & Jalal, Z., 25 May 2021, In: Journal of Medical Internet Research. 23, 5, e24190.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Mobile Applications 100%
  • Medication Adherence 84%
  • Meta-Analysis 57%
  • Systematic Reviews 56%
  • Cardiovascular Diseases 55%
  206 Downloads (Pure)

• Quantification of fibroblast growth factor 23 and N-terminal pro-B-type natriuretic peptide to identify patients with atrial fibrillation using a high-throughput platform: a validation study

  Chua, W., Law, J. P., Cardoso, V. R., Purmah, Y., Neculau, G., Jawad-Ul-Qamar, M., Russell, K., Turner, A., Tull, S. P., Nehaj, F., Brady, P., Kastner, P., Ziegler, A., Gkoutos, G. V., Pavlovic, D., Ferro, C. J., Kirchhof, P. & Fabritz, L., 3 Feb 2021, In: PLoS Medicine. 18, 2, e1003405.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • fibroblast growth factor 23 100%
  • Validation Studies 79%
  • Brain Natriuretic Peptide 79%
  • Atrial Fibrillation 63%
  • Body Mass Index 11%
  136 Downloads (Pure)

• Redefining β-blocker response in heart failure patients with sinus rhythm and atrial fibrillation: a machine learning cluster analysis

  Karwath, A., Bunting, K. V., Gill, S. K., Tica, O., Pendleton, S., Aziz, F., Barsky, A. D., Chernbumroong, S., Duan, J., Mobley, A. R., Cardoso, V. R., Slater, L., Williams, J. A., Bruce, E., Wang, X., Flather, M. D., Coats, A. J. S., Gkoutos, G. V. & Kotecha, D., 30 Aug 2021, (E-pub ahead of print) In: The Lancet. 2021, 10309, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cluster analysis 100%
  • Machine Learning 97%
  • Cluster Analysis 77%
  • Atrial Fibrillation 76%
  • Heart Failure 63%
  165 Downloads (Pure)

• Systematic, early rhythm control strategy for atrial fibrillation in patients with or without symptoms: the EAST-AFNET 4 trial

  Willems, S., Borof, K., Brandes, A., Breithardt, G., Camm, A. J., Crijns, H. J. G. M., Eckardt, L., Gessler, N., Goette, A., Haegeli, L. M., Heidbuchel, H., Kautzner, J., Ng, G. A., Schnabel, R. B., Suling, A., Szumowski, L., Themistoclakis, S., Vardas, P., van Gelder, I. C., Wegscheider, K., & 1 othersKirchhof, P., 27 Aug 2021, (E-pub ahead of print) In: European Heart Journal. ehab593.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Atrial Fibrillation 100%
  • Heart Failure 12%
  • Acute Coronary Syndrome 8%
  • Practice Guidelines 8%
  • Therapeutics 7%
  40 Downloads (Pure)

• Utility of Non-invasive Cardiac Imaging Assessment in Coronavirus Disease 2019

  Hothi, S. S., Jiang, J., Steeds, R. P. & Moody, W. E., 21 May 2021, In: Frontiers in cardiovascular medicine. 8, 663864.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Coronavirus 100%
  • Troponin 47%
  • Biomarkers 25%
  • Wounds and Injuries 19%
  • Lung Diseases 17%
  119 Downloads (Pure)
• 2020

  Beta-blocker efficacy across different cardiovascular indications: an umbrella review and meta-analytic assessment

  Ziff, O., Samra, M., Howard, J., Bromage, D., Ruschitzka, F., Francis, D. & Kotecha, D., 5 May 2020, In: BMC Medicine. 18, 1, 11 p., 103.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Meta-Analysis 100%
  • Heart Failure 97%
  • Randomized Controlled Trials 90%
  • Mortality 78%
  • Myocardial Infarction 48%
  4 Citations (Scopus)

  176 Downloads (Pure)

• Changes in quality of life, cognition and functional status following catheter ablation of atrial fibrillation

  Piccini, J. P., Todd, D. M., Massaro, T., Lougee, A., Haeusler, K. G., Blank, B., De Bono, J. P., Callans, D. J., Elvan, A., Fetsch, T., Van Gelder, I., Gentlesk, P., Grimaldi, M., Hansen, J., Hindricks, G., Al-khalidi, H., Mont, L., Nielsen, J. C., Noelker, G., De Potter, T., & 6 othersScherr, D., Schotten, U., Themistoclakis, S., Vijgen, J., Di Biase, L. & Kirchhof, P., 12 Oct 2020, (E-pub ahead of print) In: Heart. 106, 24, p. 1919-1926

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Catheter Ablation 100%
  • Atrial Fibrillation 77%
  • Cognition 68%
  • Quality of Life 56%
  • Tachycardia 54%
  2 Citations (Scopus)

  152 Downloads (Pure)

• Clinical potential of targeting fibroblast growth factor‐23 and αKlotho in the treatment of uremic cardiomyopathy

  Law, J. P., Price, A. M., Pickup, L., Radhakrishnan, A., Weston, C., Jones, A. M., McGettrick, H. M., Chua, W., Steeds, R. P., Fabritz, L., Kirchhof, P., Pavlovic, D., Townend, J. N. & Ferro, C. J., 9 Apr 2020, In: Journal of the American Heart Association. 9, 7, 15 p., e016041.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cardiomyopathies 100%
  • Chronic Renal Insufficiency 94%
  • Fibroblasts 76%
  • fibroblast growth factor 23 71%
  • Growth 51%
  3 Citations (Scopus)

  220 Downloads (Pure)

• Detection of unknown atrial fibrillation by prolonged ECG monitoring in an all-comer patient cohort and association with clinical and Holter variables

  Jawad-Ul-Qamar, M., Chua, W. W. L., Purmah, Y., Nawaz, M., Varma, C., Davis, R., Maher, A., Fabritz, L. & Kirchhof, P., 4 May 2020, In: Open Heart. 7, 1, 6 p., e001151.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Atrial Fibrillation 100%
  • Electrocardiography 91%
  • Stroke 25%
  • Comorbidity 19%
  • Heart Valve Diseases 15%
  3 Citations (Scopus)

  280 Downloads (Pure)

• Imaging assessment of mitral and aortic regurgitation: current state of the art

  Steeds, R. P. & Myerson, S. G., 28 Oct 2020, In: Heart. 106, 22, p. 1769-1776

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Citation (Scopus)

  158 Downloads (Pure)

• Importance and assessment of quality of life in symptomatic permanent atrial fibrillation: Patient focus groups from the RATE-AF trial

  Jones, J., Stanbury, M., Haynes, S., Bunting, K., Lobban, T., Camm, A. J., Calvert, M. & Kotecha, D., 28 Aug 2020, In: Cardiology. 145, 10, p. 666-675 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Focus Groups 100%
  • Atrial Fibrillation 92%
  • Quality of Life 67%
  • Comorbidity 24%
  • Patient Advocacy 13%
  2 Citations (Scopus)

  198 Downloads (Pure)

• Predicting recurrent atrial fibrillation after catheter ablation: a systematic review of prognostic models

  Dretzke, J., Chuchu, N., Agarwal, R., Herd, C., Chua, W. W. L., Fabritz, L., Bayliss, S., Kotecha, D., Deeks, J., Kirchhof, P. & Takwoingi, Y., 1 May 2020, In: Europace. 22, 5, p. 748–760

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Catheter Ablation 100%
  • Atrial Fibrillation 77%
  • Systematic Reviews 64%
  • Calibration 36%
  • Bibliographic Databases 23%
  11 Citations (Scopus)

  162 Downloads (Pure)

• Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation

  Reyat, J. S., Chua, W., Cardoso, V. R., Witten, A., Kastner, P. M., Kabir, S. N., Sinner, M. F., Wesselink, R., Holmes, A. P., Pavlovic, D., Stoll, M., Kääb, S., Gkoutos, G. V., de Groot, J. R., Kirchhof, P. & Fabritz, L., 20 Aug 2020, In: JCI Insight. 5, 16, e139179.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cardiac Myocytes 100%
  • Atrial Fibrillation 95%
  • Atrial Appendage 41%
  • Recurrence 14%
  • Biomarkers 10%
  5 Citations (Scopus)

  183 Downloads (Pure)
• 2019

  Impact of renal impairment on beta-blocker efficacy in patients with heart failure

  Beta-Blockers in Heart Failure Collaborative Group, Kotecha, D. & Gill, S., 10 Dec 2019, In: Journal of the American College of Cardiology. 74, 23, p. 2893-2904 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glomerular Filtration Rate 100%
  • Heart Failure 77%
  • Kidney 56%
  • Mortality 29%
  • Placebos 24%
  8 Citations (Scopus)

  125 Downloads (Pure)