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Application of the SMALP System to Generate Antibodies for Intact Transmembrane Proteins
Overduin, Michael
(Principal Investigator)
Dafforn, Tim
(Co-Investigator)
Biosciences
Cancer and Genomic Sciences
Overview
Fingerprint
Research output
(3)
Research output
Research output per year
2015
2015
2016
2016
3
Article
Research output per year
Research output per year
3 results
Publication Year, Title
(descending)
Publication Year, Title
(ascending)
Title
Type
Search results
2016
A method for detergent-free isolation of membrane protein with its local lipid environment
Lee, S. C.
,
Knowles, T. J.
,
Postis, V. L. G.
,
Jamshad, M.
,
Parslow, R. A.
,
Lin, Y.
,
Goldman, A.
,
Sridhar, P.
,
Overduin, M.
,
Muench, S. P.
&
Dafforn, T. R.
,
1 Jul 2016
,
In:
Nature protocols.
11
,
7
,
p. 1149–1162
14 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Detergents
100%
Membrane Proteins
79%
Lipid
65%
Lipids
62%
Environment
54%
175
Citations (Scopus)
603
Downloads (Pure)
Encapsulated membrane proteins: a simplified system for molecular simulation
Lee, S. C.
,
Khalid, S.
,
Pollock, N. L.
,
Knowles, T. J.
,
Edler, K.
,
Rothnie, A. J.
,
R T Thomas, O.
&
Dafforn, T. R.
,
Oct 2016
,
In:
Biochimica et Biophysica Acta.
1858
,
10
,
p. 2549-2557
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Membrane Proteins
100%
Simulation
75%
Protein
49%
maleic acid
42%
Styrene
42%
18
Citations (Scopus)
236
Downloads (Pure)
2015
G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent
Jamshad, M.
,
Charlton, J.
,
Lin, Y-P.
,
Routledge, S. J.
,
Bawa, Z.
,
Knowles, T. J.
,
Overduin, M.
,
Dekker, N.
,
Dafforn, T.
,
Bill, R. M.
,
Poyner, D. R.
&
Wheatley, M.
,
1 Apr 2015
,
In:
Bioscience Reports.
35
,
2
, e00188.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Detergents
100%
G-Protein-Coupled Receptors
96%
Solubilization
92%
Detergent
89%
Lipid
65%
89
Citations (Scopus)
177
Downloads (Pure)