Application of the SMALP System to Generate Antibodies for Intact Transmembrane Proteins

Overduin, Michael (Principal Investigator)
Dafforn, Tim (Co-Investigator)

Short title	Application of the SMALP System to Generate Antibodies for Intact Transmembrane Proteins
Status	Finished
Effective start/end date	1/04/13 → 30/09/14

Funding

Biotechnology & Biological Sciences Research Council

3 Article

A method for detergent-free isolation of membrane protein with its local lipid environment
Lee, S. C., Knowles, T. J., Postis, V. L. G., Jamshad, M., Parslow, R. A., Lin, Y., Goldman, A., Sridhar, P., Overduin, M., Muench, S. P. & Dafforn, T. R., 1 Jul 2016, In: Nature protocols. 11, 7, p. 1149–1162 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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175 Citations (Scopus)

661 Downloads (Pure)
Encapsulated membrane proteins: a simplified system for molecular simulation
Lee, S. C., Khalid, S., Pollock, N. L., Knowles, T. J., Edler, K., Rothnie, A. J., R T Thomas, O. & Dafforn, T. R., Oct 2016, In: Biochimica et Biophysica Acta. 1858, 10, p. 2549-2557
Research output: Contribution to journal › Article › peer-review

Open Access
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18 Citations (Scopus)

262 Downloads (Pure)
G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent
Jamshad, M., Charlton, J., Lin, Y-P., Routledge, S. J., Bawa, Z., Knowles, T. J., Overduin, M., Dekker, N., Dafforn, T., Bill, R. M., Poyner, D. R. & Wheatley, M., 1 Apr 2015, In: Bioscience Reports. 35, 2, e00188.
Research output: Contribution to journal › Article › peer-review

Open Access
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89 Citations (Scopus)

230 Downloads (Pure)