Research output per year
Research output per year
Research output
- 13 Article
- 13 results
Search results
-
2020
The thick waxy coat of mycobacteria, a protective layer against antibiotics and the host's immune system
Batt, S. M., Minnikin, D. E. & Besra, G. S., 29 May 2020, In: The Biochemical journal. 477, 10, p. 1983-2006 24 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)208 Downloads (Pure) -
2019
Development of a whole‐cell high‐throughput phenotypic screen to identify inhibitors of mycobacterial amino acid biosynthesis
Burke, C., Abrahams, K. A., Richardson, E. J., Loman, N. J., Alemparte, C., Lelievre, J. & Besra, G. S., 3 Apr 2019, In: FASEB BioAdvances. 1, 4, p. 246-254 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)153 Downloads (Pure) -
2018
AftD functions as an α1→5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core
Alderwick, L. J., Birch, H. L., Krumbach, K., Bott, M., Eggeling, L. & Besra, G. S., Mar 2018, In: The Cell Surface. 1, p. 2-14Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)153 Downloads (Pure) -
Identification and characterization of aspartyl-tRNA synthetase inhibitors against Mycobacterium tuberculosis by an integrated whole-cell target-based approach
Soto, R., Perez-Herran, E., Rodriguez, B., Duma, B. M., Cacho-Izquierdo, M., Mendoza-Losana, A., Lelievre, J., Aguirre, D. B., Ballell, L., Cox, L. R., Alderwick, L. J. & Besra, G. S., 23 Aug 2018, In: Scientific Reports. 8, 9 p., 12664.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)164 Downloads (Pure) -
The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis
Jankute, M., Alderwick, L., Moorey, A., Joe, M., Gurcha, S., Eggeling, L., Lowary, T. L., Dell, A., Pang, P-C., Yang, T., Haslam, S. M. & Besra, G., 20 Jun 2018, In: The Cell Surface. 2, p. 38-53Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)182 Downloads (Pure) -
2017
Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface
Abrahams, K. A., Cox, J. A. G., Fütterer, K., Rullas, J., Ortega-Muro, F., Loman, N. J., Moynihan, P. J., Pérez-Herrán, E., Jiménez, E., Esquivias, J., Barros, D., Ballell, L., Alemparte, C. & Besra, G. S., 25 Aug 2017, In: Scientific Reports. 7, 1, 9430.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)195 Downloads (Pure) -
Positive Diagnosis of Ancient Leprosy and Tuberculosis Using Ancient DNA and Lipid Biomarkers
Donoghue, H., Taylor, G., Stewart, G., Lee, O., Wu, H., Besra, G. & Minnikin, D., 15 Oct 2017, In: Diversity. 9, 4, p. 46Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)156 Downloads (Pure) -
2014
Benzothiazinones mediate killing of Corynebacterianeae by blocking decaprenyl phosphate recycling involved in cell wall biosynthesis
Grover, S., Alderwick, L. J., Mishra, A. K., Krumbach, K., Marienhagen, J., Eggeling, L., Bhatt, A. & Besra, G. S., 28 Feb 2014, In: Journal of Biological Chemistry. 289, 9, p. 6177-6187Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)231 Downloads (Pure) -
Biochemical and structural characterization of Mycobacterial aspartyl-tRNA synthetase aspS, a promising TB drug target
Gurcha, S. S., Veeraraghavan, U., Cox, J. A. G., Fütterer, K., Abrahams, K. A., Bhatt, A., Alderwick, L. J., Reynolds, R. C., Loman, N. J., Nataraj, V-S., Alemparte, C., Barros, D., Lloyd, A. J., Ballell, L., Hobrath, J. V. & Besra, G. S., 19 Nov 2014, In: PLoS ONE. 9, 11, e113568.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)216 Downloads (Pure) -
Elucidation of a protein-protein interaction network involved in Corynebacterium glutamicum cell wall biosynthesis as determined by bacterial two-hybrid analysis
Jankute, M., Byng, C. V., Alderwick, L. J. & Besra, G. S., Oct 2014, In: Glycoconjugate journal. 31, 6-7, p. 475-483Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)189 Downloads (Pure) -
2013
Disruption of the serine/threonine protein kinase H affects phthiocerol dimycocerosates synthesis in Mycobacterium tuberculosis
Gómez-Velasco, A., Bach, H., Rana, A. K., Cox, L. R., Bhatt, A., Besra, G. S. & Av-Gay, Y., Apr 2013, In: Microbiology (Reading, England). 159, 4, p. 726-736Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)217 Downloads (Pure) -
Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity
Stoop, E. J. M., Mishra, A. K., Driessen, N. N., van Stempvoort, G., Bouchier, P., Verboom, T., van Leeuwen, L. M., Sparrius, M., Raadsen, S. A., van Zon, M., van der Wel, N. N., Besra, G. S., Geurtsen, J., Bitter, W., Appelmelk, B. J. & van der Sar, A. M., 1 Dec 2013, In: Cellular Microbiology. 15, 12, p. 2093–2108Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)259 Downloads (Pure) -
Synthesis of α-glucan in mycobacteria involves a hetero-octameric complex of trehalose synthase TreS and Maltokinase Pep2
Roy, R., Veeraraghavan, U., Kermani, A., Scott, D. J., Hyde, E. I., Besra, G. S., Alderwick, L. J. & Fütterer, K., 18 Oct 2013, In: ACS chemical biology. 8, 10, p. 2245-2255Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)537 Downloads (Pure)