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An integrated multi-disciplinary approach to unravel complex and essential cell wall biosynthetic pathways
Besra, Del
(Principal Investigator)
Futterer, Klaus
(Co-Investigator)
Biosciences
Overview
Fingerprint
Research output
(13)
Project Details
Short title
An integrated multi-disciplinary approach to unravel complex and essential cell wall biosynthetic pathways
Status
Finished
Effective start/end date
1/01/08
→
30/06/13
Funding
THE WELLCOME TRUST
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Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Mycobacterium tuberculosis
Medicine & Life Sciences
100%
Cell Wall
Medicine & Life Sciences
99%
Corynebacterium glutamicum
Medicine & Life Sciences
92%
arabinogalactan
Medicine & Life Sciences
65%
Aspartate-tRNA Ligase
Medicine & Life Sciences
65%
Tuberculosis
Medicine & Life Sciences
64%
lipoarabinomannan
Medicine & Life Sciences
64%
araban
Medicine & Life Sciences
54%
Research output
Research output per year
2013
2013
2014
2017
2018
2020
13
Article
Research output per year
Research output per year
The thick waxy coat of mycobacteria, a protective layer against antibiotics and the host's immune system
Batt, S. M.
,
Minnikin, D. E.
&
Besra, G. S.
,
29 May 2020
,
In:
The Biochemical journal.
477
,
10
,
p. 1983-2006
24 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Mycobacterium
100%
Protective
76%
Immune System
73%
Antimicrobial Agent
64%
Lipid
63%
11
Citations (Scopus)
98
Downloads (Pure)
Development of a whole‐cell high‐throughput phenotypic screen to identify inhibitors of mycobacterial amino acid biosynthesis
Burke, C.
,
Abrahams, K. A.
,
Richardson, E. J.
,
Loman, N. J.
,
Alemparte, C.
,
Lelievre, J.
&
Besra, G. S.
,
3 Apr 2019
,
In:
FASEB BioAdvances.
1
,
4
,
p. 246-254
9 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Biosynthesis
100%
Acid
41%
Antitubercular Agent
34%
Tuberculostatic Agent
32%
Strain
16%
4
Citations (Scopus)
112
Downloads (Pure)
AftD functions as an α1→5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core
Alderwick, L. J.
,
Birch, H. L.
,
Krumbach, K.
,
Bott, M.
,
Eggeling, L.
&
Besra, G. S.
,
Mar 2018
,
In:
The Cell Surface.
1
,
p. 2-14
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
arabinogalactan
100%
Cell Wall
61%
Corynebacterium glutamicum
45%
araban
27%
Mycolic Acids
23%
7
Citations (Scopus)
110
Downloads (Pure)