An amphipathic nanostructure to extract, stabilze and purify hydrophopic proteins.

Short title	An amphipathic nanostructure to extract, stabilze and purify hydrophopic proteins.
Status	Finished
Effective start/end date	1/05/09 → 30/04/12

Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins
Jamshad, M., Grimard, V., Idini, I., Knowles, T. J., Dowle, M. R., Schofield, N., Sridhar, P., Lin, Y., Finka, R., Wheatley, M., Thomas, O. R. T., Palmer, R. E., Overduin, M., Govaerts, C., Ruysschaert, J., Edler, K. J. & Dafforn, T., Mar 2015, In: Nano Research. 8, 3, p. 774-789
Research output: Contribution to journal › Article › peer-review
100 Citations (Scopus)
Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K + channel: The power of native nanodiscs
Dörr, J. M., Koorengevel, M. C., Schäfer, M., Prokofyev, A. V., Scheidelaar, S., Van Der Cruijsen, E. A. W., Dafforn, T. R., Baldus, M. & Killian, J. A., 30 Dec 2014, In: National Academy of Sciences. Proceedings. 111, 52, p. 18607-18612
Research output: Contribution to journal › Article › peer-review

177 Citations (Scopus)
Surfactant-free purification of membrane proteins with intact native membrane environment
Jamshad, M., Lin, YP., Knowles, T., Parslow, R., Harris, C., Wheatley, M., Poyner, DR., Bill, RM., Thomas, O., Overduin, M. & Dafforn, T., 1 Jun 2011, In: Biochemical Society Transactions. 39, p. 813-818 6 p.
Research output: Contribution to journal › Article
69 Citations (Scopus)

Project Details