Yun Fan

Dr.

Accepting PhD Students

PhD projects

Yun Fan’s research centres on understanding how cell death, cell proliferation and cell differentiation are co-ordinated to maintain tissue homeostasis. This has important implications for cancer development and tissue regeneration.

Tissue homeostasis in multicellular organisms requires co-ordinated cell death (apoptosis), cell proliferation and cell differentiation. Intriguingly, apoptotic cells can also induce additional divisions of the remaining cells to compensate for cell loss - a process termed apoptosis-induced compensatory cell proliferation (CP). Recent studies have revealed that stress-induced apoptotic cells can send growth signals to trigger CP through a non-apoptotic function of caspases, a family of cysteine-proteases that normally execute apoptosis. UsingDrosophila, Dr Fan’s lab has developed unique assays to systematically identify and characterise novel CP regulators in both proliferating and differentiating tissues. Its long-term goal is to elucidate the relevance of CP regulation in tissue regeneration and tumorigenesis.

20022021

Research activity per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Fingerprint

Dive into the research topics where Yun Fan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Network

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or