Trish Lalor

Research output

Research output per year 1997 2003 2004 2005 2006 2013 2014 2017 2024

• 83 Article
• 26 Abstract
• 22 Paper
• 6 Chapter
• 9 More
  • 3 Chapter (peer-reviewed)
  • 3 Editorial
  • 3 Review article

Research output per year

Research output per year

Search results

• 2024

  Circulating myeloid populations have prognostic utility in alcohol-related liver disease

  Khan, R., Salman, S., Harford, L., Sheriff, L., Hazeldine, J., Rajoriya, N., Newsome, P. N. & Lalor, P. F., 13 Mar 2024, In: Frontiers in immunology. 15, 1330536.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Liver Diseases 100%
  • Alcohols 89%
  • Population 46%
  • Mortality 42%
  • Granulocytes 33%
  27 Downloads (Pure)
• 2023

  Decellularization of the Human Liver to Generate Native Extracellular Matrix for Use in Automated Functional Assays with Stellate Cells

  Shepherd, E. L., Northall, E., Papakyriacou, P., Safranska, K., Sorensen, K. K. & Lalor, P. F., 30 May 2023, Hepatic Stellate Cells: Methods and Protocols. 1 ed. Vol. 2669. p. 233-244 12 p. (Methods in molecular biology (Clifton, N.J.)).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Extracellular Matrix 100%
  • Liver 61%
  • Fibrosis 43%
  • Gastroenterology 33%
  • Tissue Engineering 28%

• Liver disease and cell therapy - advances made and remaining challenges

  Khan, S., Mahgoub, S., Fallatah, N., Lalor, P. F. & Newsome, P. N., 13 Apr 2023, In: Stem Cells. 41, 8

  Research output: Contribution to journal › Article › peer-review

  • Cell- and Tissue-Based Therapy 100%
  • Liver Diseases 88%
  • Clinical Studies 48%
  • End Stage Liver Disease 41%
  • Extracellular Vesicles 41%

• Postexercise muscle glycogen synthesis with glucose, galactose, and combined galactose-glucose ingestion

  Podlogar, T., Shad, B. J., Seabright, A. P., Odell, O. J., Lord, S. O., Civil, R., Salgueiro, R. B., Shepherd, E. L., Lalor, P. F., Elhassan, Y. S., Lai, Y-C., Rowlands, D. S. & Wallis, G. A., Dec 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 6, p. E672-E681

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Galactose 100%
  • Glycogen 94%
  • Eating 68%
  • Glucose 57%
  • Muscles 54%
  35 Downloads (Pure)

• TGFβ₁ priming enhances CXCR3-mediated mesenchymal stromal cell engraftment to the liver and enhances anti-inflammatory efficacy

  Garg, A., Khan, S., Luu, N., Nicholas, D. J., Day, V., King, A. L., Fear, J., Lalor, P. F. & Newsome, P. N., Mar 2023, In: Journal of Cellular and Molecular Medicine. 27, 6, p. 864-878 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mesenchymal Stem Cells 100%
  • Anti-Inflammatory Agents 82%
  • Liver 57%
  • Wounds and Injuries 21%
  • Endothelium 19%
  58 Downloads (Pure)

• The role of neutrophils in alcohol-related hepatitis

  Khan, R. S., Lalor, P. F., Thursz, M. & Newsome, P., Oct 2023, In: Journal of Hepatology. 79, 4, p. 1037-1048

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hepatitis 100%
  • Neutrophils 82%
  • Alcohols 79%
  • Liver Diseases 26%
  • Liver 16%
  44 Downloads (Pure)

• Tracer-Based Metabolic Analysis by NMR in Intact Perfused Human Liver Tissue

  Saborano, R., Shepherd, E., Günther, U. L. & Lalor, P. F., 1 Jun 2023, Metabolic Reprogramming: Methods and Protocols. 1 ed. Springer, Vol. 2675. p. 167-180 14 p. (Methods in molecular biology (Clifton, N.J.)).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Magnetic Resonance Spectroscopy 100%
  • Liver 61%
  • Non-alcoholic Fatty Liver Disease 21%
  • Metabolic Diseases 20%
  • Liver Diseases 16%
• 2022

  Editorial: Roles of Liver Sinusoidal Endothelial Cells in Liver Homeostasis and Disease

  Lalor, P. F., Huser, T. & van Grunsven, L. A., 8 Mar 2022, In: Frontiers in Physiology. 13, 3 p., 869473.

  Research output: Contribution to journal › Editorial

  Open Access

  File
  18 Downloads (Pure)

• The Contribution of Liver Sinusoidal Endothelial Cells to Clearance of Therapeutic Antibody

  James, B. H., Papakyriacou, P., Gardener, M. J., Gliddon, L., Weston, C. J. & Lalor, P. F., 14 Jan 2022, In: Frontiers in Physiology. 12, 12 p., 753833.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Endothelial Cells 100%
  • Antibodies 74%
  • Liver 69%
  • Antibodies, Monoclonal, Humanized 29%
  • Pharmacokinetics 25%
  117 Downloads (Pure)
• 2021

  Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies

  Coltman, N. J., Coke, B. A., Chatzi, K., Shepherd, E. L., Lalor, P. F., Schulz-Utermoehl, T. & Hodges, N. J., 1 Jul 2021, In: Toxicology Letters. 345, p. 34-45 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Genotoxicity 100%
  • Genotoxic 97%
  • Xenobiotic Agent 94%
  • 4-Nitroquinoline N-Oxide 70%
  • Metabolic 66%

• The impact of the NLRP3 pathway in the pathogenesis of non-alcoholic fatty liver disease and alcohol-related liver disease

  Sheriff, L. & Lalor, P., 6 May 2021, In: Livers. 1, 2, p. 68-81

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Marker 100%
  • Metabolic 92%
  • Protein 47%
  147 Downloads (Pure)
• 2020

  Alcoholic hepatitis and metabolic disturbance in female mice: a more tractable model than Nrf2-/- animals

  Sheriff, L., Khan, R. S., Saborano, R., Wilkin, R., Luu, N., Gunther, U. L., Hubscher, S. G., Newsome, P. N. & Lalor, P. F., 29 Dec 2020, In: Disease Models & Mechanisms. 13, 12, dmm046383.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Alcoholic Hepatitis 100%
  • Metabolic 58%
  • Animal Models 52%
  • Ethanol 46%
  • Oxidative Stress 35%
  1 Citation (Scopus)

  201 Downloads (Pure)

• Inhibition of vascular adhesion protein-1 modifies hepatic steatosis in vitro and in vivo

  Shepherd, E. L., Karim, S., Newsome, P. N. & Lalor, P. F., 27 Nov 2020, In: World journal of hepatology. 12, 11, p. 931-948

  Research output: Contribution to journal › Article › peer-review

• Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis

  Shepherd, E., Saborano, R., Northall, E., Matsuda, K., Ogino, H., Yashiro, H., Pickens, J., Feaver, R. E., Cole, B. K., Hoang, S. A., Lawson, M. J., Olson, M., Figler, R. A., Reardon, J. E., Nishigaki, N., Wamhoff, B. R., Gunther, U., Hirschfield, G., Erion, D. M. & Lalor, T., 20 Nov 2020, In: JHEP Reports. 2020, 100217.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ketohexokinase 100%
  • Fructose 60%
  • Psychological Inhibition 43%
  • Non-alcoholic Fatty Liver Disease 25%
  • Liver 24%
  3 Downloads (Pure)

• The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure

  Chauhan, A., Sheriff, L., Hussain, M. T., Webb, G. J., Patten, D. A., Shepherd, E. L., Shaw, R., Weston, C. J., Haldar, D., Bourke, S., Bhandari, R., Watson, S., Adams, D. H., Watson, S. P. & Lalor, P. F., Dec 2020, In: Nature Communications. 11, 1, 12 p., 1939.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • neutrophils 100%
  • Acute Liver Failure 77%
  • liver 72%
  • platelets 71%
  • Acetaminophen 69%
  8 Citations (Scopus)

  223 Downloads (Pure)
• 2019

  A framework for tracer-based metabolism in mammalian cells by NMR

  Saborano, R., Lalor, P. & Gunther, U., 21 Feb 2019, In: Scientific Reports. 9, 1, p. 2520 2520 (2019).

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Magnetic Resonance Spectroscopy 100%
  • Cell Line 52%
  • Workflow 32%
  • Metabolic Networks and Pathways 29%
  • Liver Neoplasms 29%
  10 Citations (Scopus)

  391 Downloads (Pure)

• Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

  Malehmir, M., Pfister, D., Gallage, S., Szydlowska, M., Inverso, D., Kotsiliti, E., Leone, V., Peiseler, M., Surewaard, B. G. J., Rath, D., Ali, A., Wolf, M. J., Drescher, H., Healy, M. E., Dauch, D., Kroy, D., Krenkel, O., Kohlhepp, M., Engleitner, T., Olkus, A., & 46 othersSijmonsma, T., Volz, J., Deppermann, C., Stegner, D., Helbling, P., Nombela-Arrieta, C., Rafiei, A., Hinterleitner, M., Rall, M., Baku, F., Borst, O., Wilson, C. L., Leslie, J., O'Connor, T., Weston, C. J., Adams, D. H., Sheriff, L., Teijeiro, A., Prinz, M., Bogeska, R., Anstee, N., Bongers, M. N., Notohamiprodjo, M., Geisler, T., Withers, D. J., Ware, J., Mann, D. A., Augustin, H. G., Vegiopoulos, A., Milsom, M. D., Rose, A. J., Lalor, P. F., Llovet, J. M., Pinyol, R., Tacke, F., Rad, R., Matter, M., Djouder, N., Kubes, P., Knolle, P. A., Unger, K., Zender, L., Nieswandt, B., Gawaz, M., Weber, A. & Heikenwalder, M., 1 Apr 2019, In: Nature Medicine. 25, 4, p. 641-655 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Intrahepatic 100%
  • Fatty Liver 63%
  • Liver Neoplasms 59%
  • Ticagrelor 54%
  • Sulindac 48%
  74 Citations (Scopus)

  1620 Downloads (Pure)
• 2018

  Could endothelial TGFβ signaling be a promising new target for liver disease?

  Adams, D. H., Shepherd, E. L. & Lalor, P. F., 30 May 2018, (E-pub ahead of print) In: Expert review of gastroenterology & hepatology. 12, 7, p. 637-639 3 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

  File
  147 Downloads (Pure)

• Liver sinusoidal endothelial cells - gatekeepers of hepatic immunity

  Shetty, S., Lalor, P. F. & Adams, D. H., 29 May 2018, (E-pub ahead of print) In: Nature Reviews. Gastroenterology & Hepatology.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Immunity 100%
  • Endothelial Cells 90%
  • Liver 63%
  • Capillaries 23%
  • Vascular Endothelium 13%
  71 Citations (Scopus)

  1027 Downloads (Pure)

• Models for predicting risk of acute kidney injury after liver surgery

  Rahman, H-U., Bhogal, R. & Lalor, P., 16 May 2018, In: OBM Hepatology and Gastroenterology. 2, 2, 007.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Acute Kidney Injury 100%
  • Liver 54%
  • Surgical Blood Loss 19%
  • Liver Transplantation 11%
  • PubMed 10%
  174 Downloads (Pure)

• Scientific Business Abstracts of the 112th Annual Meeting of the Association of Physicians of Great Britain and Ireland

  Chauhan, A., Lalor, T., Watson, S., Adams, D., Farrah, T. E., Anand, A., Kimmitt, R., Mills, N. L., Webb, D. J., Dhaun, N., Kalla, R., Adams, A., Vatn, S., Bonfliglio, F., Nimmo, E., Kennedy, N., Ventham, N., Vatn, M., Ricanek, P., Halfvarson, J., & 85 othersSoderhollm, J., Pierik, M., Torkvist, L., Gomollon, F., Gut, I., Jahnsen, J., Satsangi, J., Body, R., Almashali, M., McDowell, G., Taylor, P., Lacey, A., Rees, A., Dayan, C., Lazarus, J., Nelson, S., Okosieme, O., Corcoran, D., Young, R., Ciadella, P., McCartney, P., Bajrangee, A., Hennigan, B., Collison, D., Carrick, D., Shaukat, A., Good, R., Watkins, S., McEntegart, M., Watt, J., Welsh, P., Sattar, N., McConnachie, A., Oldroyd, K., Berry, C., Parks, T., Auckland, K., Mentzer, A. J., Kado, J., Mirabel, M. M., Kauwe, J. K., Robson, K. J., Mittal, B., Steer, A. C., Hill, A. V. S., Akbar, M., Forrester, M., Virlan, A. T., Gilmour, A., Wallace, C., Paterson, C., Reid, D., Siebert, S., Porter, D., Liversidge, J., McInnes, I., Goodyear, C., Athwal, V., Pritchett, J., Zaitoun, A., Irving, W., Guha, I. N., Hanley, N. A., Hanley, K. P., Briggs, T., Reynolds, J., Rice, G., Bondet, V., Bruce, E., Crow, Y., Duffy, D., Parker, B., Bruce, I., Martin, K., Pritchett, J., Aoibheann Mullan, M., Llewellyn, J., Athwal, V., Zeef, L., Farrow, S., Streuli, C., Henderson, N., Friedman, S., Hanley, N. A. & Hanley, K. P., 1 Dec 2018, In: QJM : monthly journal of the Association of Physicians. 111, 12, p. 920-924 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2017

  Blocking platelet activation enhances neutrophil driven liver repair after acute toxic liver injury

  Chauhan, A., Adams, D., Watson, S. & Lalor, P., 2017, In: Journal of Hepatology.

  Research output: Contribution to journal › Article › peer-review

• Changes in human hepatic metabolism in steatosis and cirrhosis

  Schofield, Z., Reed, M. A. C., Newsome, P., Adams, D., Gunther, U. & Lalor, P., 21 Apr 2017, In: World Journal of Gastroenterology. 23, 15, p. 2685-2695 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fibrosis 100%
  • Liver 69%
  • Non-alcoholic Fatty Liver Disease 62%
  • Alcohols 57%
  • Metabolomics 42%
  15 Citations (Scopus)

  228 Downloads (Pure)

• Development of a novel murine model of acute alcoholic hepatitis

  Wilkin, R., Lalor, P., Parker, R. & Newsome, P., 2017, In: Journal of Hepatology.

  Research output: Contribution to journal › Article › peer-review

• Dynamic Regulation of Canonical TGF beta-Signalling by the Endothelial Transcription Factor ERG Protects from Liver Fibrogenesis

  Dufton, N., Peghaire, C., Osuna-Almagro, L., Raimondi, C., Kalna, V., Chuahan, A., Webb, G., Yang, Y., Birdsey, G., Lalor, P., Mason, J., Adams, D. & Randi, A., 2017, In: Journal of Vascular Research. 54, S1, p. 6-7 2 p.

  Research output: Contribution to journal › Abstract › peer-review
  1 Citation (Scopus)

• Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis

  Dufton, N. P., Peghaire, C. R., Osuna-Almagro, L., Raimondi, C., Kalna, V., Chuahan, A., Webb, G., Yang, Y., Birdsey, G. M., Lalor, P., Mason, J. C., Adams, D. H. & Randi, A. M., 12 Oct 2017, In: Nature Communications. 8, 895.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tumor Necrosis Factor Inhibitor 100%
  • genes 56%
  • Ablation 56%
  • liver 53%
  • Biological Marker 43%
  37 Citations (Scopus)

  245 Downloads (Pure)

• Introduction to Lymphocyte Trafficking in Disease

  Lalor, P. F. & Hepburn, E. A., 28 Mar 2017, T-Cell Trafficking: Methods and Protocols. Rainger, G. E. & Mcgettrick, H. M. (eds.). Springer, Vol. 1591. p. 169-176 8 p. (Methods in Molecular Biology ).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  • Lymphocytes 100%
  • Adaptive Immunity 49%
  • Inflammatory Bowel Diseases 45%
  • Integrins 45%
  • Chemokines 45%
  3 Citations (Scopus)

• In Vitro and Ex Vivo Models to Study T Cell Migration Through the Human Liver Parenchyma

  Wiggins, B. G., Aliazis, K., Davies, S. P., Hirschfield, G., Lalor, P. F., Reynolds, G. & Stamataki, Z., 28 Mar 2017, T-Cell Trafficking: Methods and Protocols. Rainger, G. E. & Mcgettrick, H. M. (eds.). Springer, Vol. 1591. p. 195-214 20 p. (Methods in Molecular Biology).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  • Cell Movement 100%
  • T-Lymphocytes 75%
  • Liver 62%
  • In Vitro Techniques 53%
  • Kupffer Cells 21%

• Role of CLEC-2-driven platelet activation in the pathogenesis of toxic liver damage

  Chauhan, A., Lalor, P., Watson, S. & Adams, D., 2017, In: The Lancet. 389, 1, p. 533

  Research output: Contribution to journal › Article › peer-review

  • Platelet Activation 100%
  • Poisons 67%
  • Liver 46%
  • Acute Liver Failure 35%
  • Acetaminophen 32%

• Using Ex Vivo Liver Organ Cultures to Measure Lymphocyte Trafficking

  Wiggins, B. G., Stamataki, Z. & Lalor, P. F., 28 Mar 2017, T-Cell Trafficking: Methods and Protocols. Rainger, G. E. & Mcgettrick, H. M. (eds.). Springer, Vol. 1591. p. 177-194 18 p. (Methods in Molecular Biology).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  • Organ Culture Techniques 100%
  • Lymphocytes 58%
  • Liver 43%
  • Chemokines 26%
  • Wounds and Injuries 13%
• 2016

  Blocking platelet activation dramatically accelerates liver recovery from acetaminophen induced sterile liver injury

  Chauhan, A., Bourke, S., Adams, D. H., Watson, S. P. & Lalor, P. F., 1 Oct 2016, In: Hepatology. 64, S1, p. 15A 29.

  Research output: Contribution to journal › Abstract › peer-review

  Open Access

• Human intrahepatic T cells are functional, require IL-2 from effector cells for survival, and are susceptible to Fas ligand-mediated apoptosis

  Chen, Y-Y., Jeffery, H. C., Hunter, S., Bhogal, R., Birtwistle, J., Kaur Braitch, M., Roberts, S., Ming, M., Hannah, J., Thomas, C., Adali, G., Hubscher, S., Syn, W-K., Afford, S., Lalor, P. F., Adams, D. H. & Oo, Y. H., Jul 2016, In: Hepatology. 64, 1, p. 138–150 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fas Ligand Protein 100%
  • Interleukin-2 73%
  • Cell Survival 62%
  • T-Lymphocytes 50%
  • Apoptosis 50%
  44 Citations (Scopus)

  226 Downloads (Pure)

• Murine Models of Acute Alcoholic Hepatitis and Their Relevance to Human Disease

  Wilkin, R. J. W., Lalor, P. F., Parker, R. & Newsome, P. N., Apr 2016, In: The American Journal of Pathology. 186, 4, p. 748–760

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Alcoholic Hepatitis 100%
  • Alcohols 40%
  • Liver 37%
  • Phenotype 32%
  • Diet 24%
  19 Citations (Scopus)

  322 Downloads (Pure)

• Platelets: no longer bystanders in liver disease

  Chauhan, A., Adams, D. H., Watson, S. P. & Lalor, P. F., 21 Oct 2016, In: Hepatology. 64, 5, p. 1774–1784

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Liver Diseases 100%
  • Blood Platelets 92%
  • Liver 61%
  • Endothelium 17%
  • Leukocytes 15%
  52 Citations (Scopus)

  235 Downloads (Pure)
• 2015

  Drug-Induced Defatting of Fatty Hepatocytes as an In Vitro Model for Metabolic Preconditioning of Steatotic Livers before Transplantation

  Widmer, J. D., Wilhelm, A., Lalor, P. F., Adams, D. H., Mergental, H., Afford, S. C. & Weston, C. J., 1 Jul 2015, In: Transplantation. 99, 1, p. 117-118 2 p.

  Research output: Contribution to journal › Article › peer-review

• Dug-Induced Defatting of Fatty Hepatocytes as an In Vitro Model for Metabolic Preconditioning of Steatotic Livers before Transplantation

  Widmer, J. D., Wilhelm, A., Lalor, P. F., Adams, D. H., Mergental, H., Afford, S. C. & Weston, C. J., 2015, In: Transplantation.

  Research output: Contribution to journal › Article › peer-review
• 2014

  A flow adhesion assay to study leucocyte recruitment to human hepatic sinusoidal endothelium under conditions of shear stress

  Shetty, S., Weston, C. J., Adams, D. H. & Lalor, P. F., 21 Mar 2014, In: Journal of Visualized Experiments. 85, e51330.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Liver 100%
  • Shear Stress 99%
  • Assays 97%
  • Shear stress 76%
  • Adhesion 76%
  22 Citations (Scopus)

  249 Downloads (Pure)

• Development of hepatocellular carcinoma in a murine model of nonalcoholic steatohepatitis induced by use of a high-fat/fructose diet and sedentary lifestyle

  Dowman, J. K., Hopkins, L. J., Reynolds, G. M., Nikolaou, N., Armstrong, M. J., Shaw, J. C., Houlihan, D. D., Lalor, P. F., Tomlinson, J. W., Hübscher, S. G. & Newsome, P. N., May 2014, In: The American Journal of Pathology. 184, 5, p. 1550-61 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Fructose 100%
  • Sedentary Behavior 94%
  • Non-alcoholic Fatty Liver Disease 94%
  • High Fat Diet 87%
  • Hepatocellular Carcinoma 70%
  57 Citations (Scopus)

• Dysregulated hepatic expression of glucose transporters in chronic disease: contribution of semicarbazide-sensitive amine oxidase to hepatic glucose uptake

  Karim, S., Liaskou, E., Fear, J., Garg, A., Reynolds, G., Claridge, L., Adams, D. H., Newsome, P. N. & Lalor, P. F., 15 Dec 2014, In: American journal of physiology. Gastrointestinal and liver physiology. 307, 12, p. G1180-90

  Research output: Contribution to journal › Article › peer-review

  • Amine Oxidase (Copper-Containing) 100%
  • Facilitative Glucose Transport Proteins 80%
  • Chronic Disease 51%
  • Glucose 43%
  • Blood Vessels 40%
  13 Citations (Scopus)

  2 Downloads (Pure)

• Efferocytosis in the liver parenchyma: how human hepatocytes clear dead cells

  Davies, S., Weight, N., Nakum, S., Lalor, P. & Stamataki, Z., 2014, In: Immunology.

  Research output: Contribution to journal › Article › peer-review

• LYMPHOTOXIN-beta RECEPTOR SIGNALLING LINKS STEATOHEPATITIS, HYPER-LIPIDEMIA AND ATHEROSCLEROSIS

  Apta, B., Harrison, M. J., Benezech, C., Karim, S., Ware, C. F., Lalor, P. F., Caamano, J. H. & Rainger, G. E., 2014, In: Atherosclerosis. 232, 2, p. e4

  Research output: Contribution to journal › Article › peer-review

• Non-enzymatic dissociation of human mesenchymal stromal cells improves chemokine-dependent migration and maintains immunosuppressive function

  Garg, A., Houlihan, D. D., Aldridge, V., Suresh, S., Li, K. K., King, A. L., Sutaria, R., Fear, J., Bhogal, R. H., Lalor, P. F. & Newsome, P. N., Apr 2014, In: Cytotherapy. 16, 4, p. 545-59 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Chemokines 100%
  • Mesenchymal Stem Cells 95%
  • Immunosuppressive Agents 88%
  • Buffers 49%
  • Chemokine Receptors 25%
  25 Citations (Scopus)

• PTU-140 Intrahepatic Tregs Are Plastic But Functional And Biliary Epithelial Cells Support Their Fate

  Chen, Y-Y., Hannah, J., Birtwistle, J., Basso, I. N., Lalor, P., Adams, D. H. & Oo, Y. H., 2014, In: Gut. 63, 1

  Research output: Contribution to journal › Article › peer-review

  • Plastics 100%
  • Epithelial Cells 74%
  • Liver 53%
  • Interleukin-2 34%
  • Cytokine Receptors 31%

• TGF beta 1 STIMULATION OF HUMAN BONE MARROW MESENCHYMAL STEM CELLS (MSC) ENHANCES THEIR HEPATIC ENGRAFTMENT AND THERAPEUTIC EFFECT IN INJURED LIVER VIA UPREGULATION OF CXCR3 FUNCTION

  Garg, A., Davies, N. J., Aldridge, V., King, A. L., Ward, S. T., Li, K. -K., Bernstein, R., Desai, S., Fear, J., Lalor, P. F. & Newsome, P. N., 2014, In: Journal of Hepatology.

  Research output: Contribution to journal › Article › peer-review

• Top-down and bottom-up identification of proteins by liquid extraction surface analysis mass spectrometry of healthy and diseased human liver tissue

  Sarsby, J., Martin, N. J., Lalor, P. F., Bunch, J. & Cooper, H. J., 1 Nov 2014, In: Journal of the American Society for Mass Spectrometry. 25, 11, p. 1953-1961

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Surface Analysis 100%
  • Mass Spectrometry 86%
  • Liver Diseases 80%
  • Liquid 51%
  • Protein 39%
  65 Citations (Scopus)

  321 Downloads (Pure)
• 2013

  An in vitro model of human acute ethanol exposure that incorporates CXCR3- and CXCR4-dependent recruitment of immune cells

  Karim, S., Liaskou, E., Hadley, S., Youster, J., Faint, J., Adams, D. H. & Lalor, P. F., Mar 2013, In: Toxicological Sciences. 132, 1, p. 131-41 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ethanol 100%
  • Lymphocytes 61%
  • Liver 61%
  • Alcoholic Liver Diseases 55%
  • In Vitro Techniques 51%
  17 Citations (Scopus)

  1 Downloads (Pure)

• Characterization of adhesion molecule and chemokine expression by tumour endothelium isolated from colorectal cancer

  Hepburn, E. A., Ward, S. T., Suresh, S., Hejmadi, R. K., Ismail, T. & Lalor, P. F., 2013, In: Immunology.

  Research output: Contribution to journal › Article › peer-review

• Common lymphatic endothelial and vascular endothelial receptor-1 mediates the transmigration of regulatory T cells and B cells across hepatic sinusoidal endothelium

  Shetty, S., Weston, C., Bruns, T., Oo, Y. H., Westerlund, N., Stamataki, Z., Youster, J., Hubscher, S., Salmi, M., Jalkanen, S., Lalor, P. F. & Adams, D. H., 2013, In: The Lancet.

  Research output: Contribution to journal › Article › peer-review

• Formal lithium fixation improves direct analysis of lipids in tissue by mass spectrometry

  Griffiths, R. L., Sarsby, J., Guggenheim, E. J., Race, A. M., Steven, R. T., Fear, J., Lalor, P. F. & Bunch, J., 6 Aug 2013, In: Analytical Chemistry. 85, 15, p. 7146-53 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lipid 100%
  • Mass Spectrometry 96%
  • Lithium Salt 65%
  • Adduct 61%
  • Oil Red O 49%
  17 Citations (Scopus)

• Hepatic sinusoidal endothelium avidly binds platelets in an integrin-dependent manner, leading to platelet and endothelial activation and leukocyte recruitment

  Lalor, P. F., Herbert, J., Bicknell, R. & Adams, D. H., 1 Mar 2013, In: American journal of physiology. Gastrointestinal and liver physiology. 304, 5, p. G469-78

  Research output: Contribution to journal › Article › peer-review

  • Platelet Activation 100%
  • Integrins 85%
  • Endothelium 80%
  • Leukocytes 72%
  • Blood Platelets 71%
  44 Citations (Scopus)