Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where Tim Knowles is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily
Parr, R. J., Santin, Y. G., Ratkevičiūte, G., Caulton, S. G., Radford, P., Gurvič, D., Jenkins, M., Doyle, M. T., Mead, L., Silale, A., van den Berg, B., Knowles, T. J., Sockett, R. E., Stansfeld, P. J., Laloux, G. & Lovering, A. L., 5 Jul 2025, In: Nature Communications. 16, 1, 14 p., 6213.Research output: Contribution to journal › Article › peer-review
Open AccessFile46 Downloads (Pure) -
HDAC6-dependent deacetylation of SAE2 enhances SUMO1 conjugation for mitotic integrity
Lanz, A. J., Walker, A. K., Jamshad, M., Garvin, A. J., Stewart, M., Wotherspoon, P., Cooper, B. F., Mackintosh, M., Crutchley, O., Knowles, T. J. & Morris, J. R., 20 Aug 2025, (E-pub ahead of print) In: EMBO Journal. 27 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Downloads (Pure) -
An octameric PqiC toroid stabilises the outer-membrane interaction of the PqiABC transport system
Cooper, B. F., Ratkevičiūtė, G., Clifton, L. A., Johnston, H., Holyfield, R., Hardy, D. J., Caulton, S. G., Chatterton, W., Sridhar, P., Wotherspoon, P., Hughes, G. W., Hall, S. C., Lovering, A. L. & Knowles, T. J., 12 Jan 2024, In: EMBO Reports. 25, 1, p. 82-101 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile206 Downloads (Pure) -
Distance tuneable integral membrane protein containing floating bilayers via in situ directed self-assembly
Hall, S. C. L., Hardy, D. J., Bragginton, É. C., Johnston, H., Onose, T., Holyfield, R., Sridhar, P., Knowles, T. J. & Clifton, L. A., 24 Jun 2024, (E-pub ahead of print) In: Nanoscale.Research output: Contribution to journal › Article › peer-review
Open AccessFile64 Downloads (Pure) -
Structure of the MlaC-MlaD complex reveals molecular basis of periplasmic phospholipid transport
Wotherspoon, P., Johnston, H., Hardy, D. J., Holyfield, R., Bui, S., Ratkevičiūtė, G., Sridhar, P., Colburn, J., Wilson, C. B., Colyer, A., Cooper, B. F., Bryant, J. A., Hughes, G. W., Stansfeld, P. J., Bergeron, J. R. C. & Knowles, T. J., 30 Jul 2024, In: Nature Communications. 15, 1, 15 p., 6394.Research output: Contribution to journal › Article › peer-review
Open AccessFile167 Downloads (Pure)
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Determining novel pathways of predator lipid shuttling
Knowles, T. (Co-Investigator) & Lovering, A. (Principal Investigator)
1/05/25 → 30/04/28
Project: Research
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Native ambient mass spectrometry for membrane proteins
Cooper, H. (Principal Investigator), Knowles, T. (Co-Investigator) & Dafforn, T. (Researcher)
Engineering & Physical Science Research Council
1/12/23 → 30/11/27
Project: Research Councils
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Unshackling Membrane Protein Research : New Amphiphilic copolymers for Extraction of Stable, Active Membrane Proteins
Knowles, T. (Principal Investigator) & Dafforn, T. (Researcher)
1/03/22 → 28/02/27
Project: Research
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A mass spectrometer for structural biology and top-down protein identification
Morris, J. (Co-Investigator), Watson, S. (Co-Investigator), Leney, A. (Principal Investigator), Carlomagno, T. (Co-Investigator), Lovering, A. (Co-Investigator), Cox, L. (Co-Investigator), Smerdon, S. (Co-Investigator), Tomlinson, M. (Co-Investigator), Knowles, T. (Co-Investigator), Grant, M. (Co-Investigator), Calebiro, D. (Co-Investigator), Cooper, H. (Co-Investigator), Jackson, R. (Co-Investigator) & Wilson, A. (Co-Investigator)
Biotechnology & Biological Sciences Research Council
1/08/24 → 31/07/25
Project: Research Councils
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An in vitro gram-negative envelope mimetic: a new way to study membrane biology
Huber, D. (Co-Investigator) & Knowles, T. (Principal Investigator)
Biotechnology & Biological Sciences Research Council
1/11/23 → 31/10/24
Project: Research Councils
Activities
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Rethinking the Mla pathway: Evidence for anterograde lipid trafficking in gram-negative bacteria
Knowles, T. (Chair)
24 Jun 2018Activity: Academic and Industrial events › Guest lecture or Invited talk
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Rethinking the Mla pathway: Evidence for anterograde lipid trafficking in gram-negative bacteria
Knowles, T. (Chair)
12 Jun 2018Activity: Academic and Industrial events › Guest lecture or Invited talk
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Viva Examination
Knowles, T. (Examiner), Casas-Mao, D. (Participant) & Hill, P. (Examiner)
18 May 2018Activity: Examination
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Nanoscale (Journal)
Knowles, T. (Chair), Wheatley, M. (Chair), Dafforn, T. (Chair), Rothnie, A. (Chair), Edler, K. J. (Chair), Arnold, T. (Chair), Hall, S. (Chair), Tognoloni, C. (Chair), Charlton, J. (Chair), Bragginton, E. C. (Chair) & Sridhar, P. (Chair)
2018Activity: Publication peer-review and editorial work › Publication peer-review
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Methods (Journal)
Knowles, T. (Peer reviewer)
2018Activity: Publication peer-review and editorial work › Publication peer-review
Press/Media
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HWB-NMR Marketing
Knowles, T., Whittaker, S., Wotherspoon, P. & Choudhury, N.
17/07/18
1 Media contribution
Press/Media: Press / Media