Research output per year
Research output per year
Research output
- 10 Article
- 10 results
Search results
-
2024
PARC: a phase I/II study evaluating the safety and activity of pegylated recombinant human arginase BCT-100 in relapsed/refractory cancers of children and young adults
Fenwick, N., Weston, R., Wheatley, K., Hodgson, J., Marshall, L., Elliott, M., Makin, G., Ng, A., Brennan, B., Lowis, S., Adamski, J., Kilday, J. P., Cox, R., Gattens, M., Moore, A., Trahair, T., Ronghe, M., Campbell, M., Campbell, H., Williams, M. W., & 10 others, 31 Jan 2024, In: Frontiers in Oncology. 14, 9 p., 1296576.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Downloads (Pure) -
2023
Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment
Panetti, S., McJannett, N. J., Fultang, L., Booth, S., Gneo, L., Scarpa, U., Smith, C., Vardon, A., Vettore, L., Whalley, C., Pan, Y., Varnai, C., Endou, H., Barlow, J., Tennant, D. A., Beggs, A. D., Mussai, F. J. & Santo, C. D., 9 May 2023, In: Blood Advances. 7, 9, p. 1754-1761 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Downloads (Pure) -
Using temporal recalibration to improve the calibration of risk prediction models in competing risk settings when there are trends in survival over time
Booth, S., Mozumder, S. I., Archer, L., Ensor, J., Riley, R. D., Lambert, P. C. & Rutherford, M. J., 13 Sept 2023, (E-pub ahead of print) In: Statistics in Medicine. 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Downloads (Pure) -
2022
Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment
Stavrou, V., Fultang, L., Booth, S., De Simone, D., Bartnik, A., Scarpa, U., Gneo, L., Panetti, S., Potluri, S., Almowaled, M., Barlow, J., Jankevics, A., Lloyd, G., Southam, A., Priestman, D. A., Cheng, P., Dunn, W., Platt, F., Endou, H., Craddock, C., & 3 others, 13 Aug 2022, (E-pub ahead of print) In: Cancer Immunology Immunotherapy. 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Downloads (Pure) -
2020
Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity
Fultang, L., Booth, S., Yogev, O., Costa, B. M. D., Tubb, V., Panetti, S., Stavrou, V., Scarpa, U., Jankevics, A., Lloyd, G., Southam, A. D., Lee, S. P., Dunn, W., Chesler, L., Mussai, F. J. & Santo, C. D., 3 Sept 2020, In: Blood. 10, p. 1155-1160 6 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
2019
MDSC targeting with Gemtuzumab ozogamicin restores T cell immunity and immunotherapy against cancers
Fultang, L., Panetti, S., Ng, M., Collins, P., Graef, S., Rizkalla, N., Booth, S., Richard, L., Noyvert, B., Shannon-Lowe, C., Middleton, G., Mussai, F. & De Santo, C., 1 Sept 2019, In: EBioMedicine. 47, p. 235-246 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile38 Citations (Scopus)257 Downloads (Pure) -
2018
Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma
Fultang, L., Gamble, L. D., Gneo, L., Berry, A. M., Egan, S. A., De Bie, F., Yogev, O., Eden, G. L., Booth, S., Brownhill, S., Vardon, A., McConville, C. M., Cheng, P. N., Norris, M. D., Etchevers, H. C., Murray, J., Ziegler, D. S., Chesler, L., Schmidt, R., Burchill, S. A., & 3 others, 13 Dec 2018, (E-pub ahead of print) In: Cancer Research.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)146 Downloads (Pure) -
Targeting the arginine metabolic brake enhances immunotherapy for leukaemia
Mussai, F., Wheat, R., Sarrou, E., Booth, S., Stavrou, V., Fultang, L., Perry, T., Kearns, P., Cheng, P., Keehsan, K., Craddock, C. & De Santo, C., 28 Nov 2018, In: International Journal of Cancer.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)236 Downloads (Pure) -
The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100
De Santo, C., Booth, S., Vardon, A., Cousins, A., Tubb, V., Perry, T., Noyvert, B., Beggs, A., Ng, M., Halsey, C., Kearns, P., Cheng, P. & Mussai, F., 1 Apr 2018, In: International Journal of Cancer. 142, 7, p. 1490-1502 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)193 Downloads (Pure) -
2013
Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment
Mussai, F., De Santo, C., Abu-Dayyeh, I., Booth, S., Quek, L., McEwen-Smith, R. M., Qureshi, A., Dazzi, F., Vyas, P. & Cerundolo, V., 1 Aug 2013, In: Blood. 122, 5, p. 749-58 10 p.Research output: Contribution to journal › Article › peer-review
135 Citations (Scopus)