Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 11 Sustainable Cities and Communities
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Collaborations and top research areas from the last five years
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11β hydroxysteroid dehydrogenase type 1 transgenic mesenchymal stem cells attenuate inflammation in models of sepsis
Mahida, R. Y., Yuan, Z., Kolluri, K. K., Scott, A., Parekh, D., Hardy, R. S., Matthay, M. A., Perkins, G. D., Janes, S. M. & Thickett, D. R., 5 Jul 2024, In: Frontiers in Bioengineering and Biotechnology. 12, 15 p., 1422761.Research output: Contribution to journal › Article › peer-review
Open AccessFile64 Downloads (Pure) -
Inflammation Dynamically Regulates Steroid Hormone Metabolism and Action within Macrophages in Rheumatoid Arthritis
Martin, C. S., Crastin, A., Sagmeister, M. S., Kalirai, M. S., Turner, J. D., MacDonald, L., Kurowska-Stolarska, M., Scheel-Toellner, D., Taylor, A. E., Gilligan, L. C., Storbeck, K., Price, M., Gorvin, C. M., Filer, A., Mahida, R., Clark, A. R., Jones, S. W., Raza, K., Hewison, M. & Hardy, R. S., Jul 2024, In: Journal of Autoimmunity. 147, 13 p., 103263.Research output: Contribution to journal › Article › peer-review
Open AccessFile101 Downloads (Pure) -
Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an ARDS Model
Ahmad, S., Wrennall, J. A., Goriounova, A. S., Sekhri, M., Iskarpatyoti, J. A., Ghosh, A., Abdelwahab, S. H., Voeller, A., Rai, M., Mahida, R. Y., Krajewski, K., Ignar, D. M., Greenbaum, A., Moran, T. P., Tilley, S. L., Thickett, D. R., Sassano, M. F. & Tarran, R., Mar 2024, In: American Journal of Respiratory and Critical Care Medicine. 209, 6, p. 703–715 13 p.Research output: Contribution to journal › Article › peer-review
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Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon β
O’Neil, J. D., Bolimowska, O. O., Clayton, S. A., Tang, T., Daley, K. K., Lara-Reyna, S., Warner, J., Martin, C. S., Mahida, R. Y., Hardy, R. S., Arthur, J. S. C. & Clark, A. R., 24 Oct 2023, In: Frontiers in immunology. 14, 17 p., 1190261.Research output: Contribution to journal › Article › peer-review
Open AccessFile106 Downloads (Pure) -
Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS
Mahida, R. Y., Lax, S., Bassford, C. R., Scott, A., Parekh, D., Hardy, R. S., Naidu, B., Matthay, M. A., Stewart, P. M., Cooper, M. C., Perkins, G. D. & Thickett, D. R., 27 Apr 2023, In: Frontiers in immunology. 14, 14 p., 1159831.Research output: Contribution to journal › Article › peer-review
Open AccessFile75 Downloads (Pure)
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Understanding the role of neutrophil extracellular traps-associated S100A12 in thrombo-inflammation during sepsis
Rayes, J. (Principal Investigator) & Mahida, R. (Co-Investigator)
1/11/23 → 31/10/26
Project: Research
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Extracellular vesicles and their cargo in the pathogenesis of acute respiratory distress syndrome and pulmonary fibrosis sequelae
Scott, A. (Researcher), Mahida, R. (Principal Investigator), Parekh, D. (Researcher) & Thickett, D. (Researcher)
1/10/22 → 30/09/27
Project: Research Councils
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Weighing evidence for microbiome targeting functional foods as interventions for preventing respiratory tract viral infections and recovery post infection.
Veiga Sardeli, A. (Co-Investigator), Mahida, R. (Co-Investigator) & Duggal, N. (Principal Investigator)
Biotechnology & Biological Sciences Research Council
1/04/25 → 30/09/25
Project: Research Councils
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BRC CF4: Mapping and tracking inflammatory platelets and their extracellular vesicles to improve sepsis outcomes
Rayes, J. (Principal Investigator) & Mahida, R. (Co-Investigator)
1/09/24 → 28/02/26
Project: Research
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Can combined cellular and 11beta-hydroxysteroid dehydrogenase-1 gene therapy attenuate inflammation in acute respiratory distress syndrome
Mahida, R. (Principal Investigator) & Thickett, D. (Co-Investigator)
3/08/16 → 2/11/19
Project: Research Councils