Paul Moss

Research output

Research output per year 2000 2005 2010 2012 2015 2016 2017 2021 2022 2023 2024 2024

• 234 Article
• 11 Letter
• 9 Review article
• 5 Comment/debate
• 10 More
  • 5 Preprint
  • 2 Conference contribution
  • 2 Editorial
  • 1 Paper

Research output per year

Research output per year

Search results

• 2024

  Accelerated immune ageing is associated with COVID-19 disease severity

  PHOSP-COVID study collaborative group & ISARIC4C Investigators, 11 Jan 2024, In: Immunity & Ageing. 21, 1, 18 p., 6.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Survivors 100%
  • T-Lymphocytes 94%
  • Phenotype 45%
  • Acute Disease 40%
  • Natural Killer Cells 35%
  41 Downloads (Pure)

• Association between antibody responses post-vaccination and severe COVID-19 outcomes in Scotland

  Macdonald, C., Palmateer, N., McAuley, A., Lindsay, L., Hasan, T., Hameed, S. S., Hall, E., Jeffrey, K., Grange, Z., Gousias, P., Mavin, S., Jarvis, L., Cameron, J. C., Daines, L., Tibble, H., Simpson, C. R., McCowan, C., Katikireddi, S. V., Rudan, I., Fagbamigbe, A. F., & 6 othersRitchie, L., Swallow, B., Moss, P., Robertson, C., Sheikh, A. & Murray, J., 14 Jun 2024, In: NPJ vaccines. 9, 1, 12 p., 107.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Scotland 100%
  • Antibody Formation 77%
  • Vaccination 69%
  • Multimorbidity 58%
  • Antibodies 47%
  49 Downloads (Pure)

• Author Correction: Safety outcomes following COVID-19 vaccination and infection in 5.1 million children in England

  Copland, E., Patone, M., Saatci, D., Handunnetthi, L., Hirst, J., Hunt, D. P. J., Mills, N. L., Moss, P., Sheikh, A., Coupland, C. A. C., Harnden, A., Robertson, C. & Hippisley-Cox, J., 8 Jul 2024, In: Nature Communications. 15, 1, 5723.

  Research output: Contribution to journal › Comment/debate

  Open Access

  File
  9 Downloads (Pure)

• CD36 regulates macrophage and endothelial cell activation and multinucleate giant cell formation in anti neutrophil cytoplasm antibody vasculitis

  Zhang, X., King, C., Dowell, A., Moss, P., Harper, L., Chanouzas, D., Ruan, X. & Salama, A. D., Mar 2024, In: Clinical Immunology. 260, 11 p., 109914.

  Research output: Contribution to journal › Article › peer-review

  • Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 100%
  • Giant Cells 74%
  • Vasculitis 71%
  • Cytoplasm 56%
  • Neutrophils 54%

• CD70 identifies alloreactive T cells and represents a potential target for prevention and treatment of acute GvHD

  Verma, K., Croft, W., Margielewska-Davies, S., Pearce, H., Stephens, C., Diaconescu, D., Bevington, S., Craddock, C., Amel-Kashipaz, R., Zuo, J., Kinsella, F. AM. & Moss, P., 19 Jul 2024, (E-pub ahead of print) In: Blood Advances. bloodadvances.2024012909.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  14 Downloads (Pure)

• Corrigendum to ‘Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study’ [The Lancet Regional Health – Europe 35 (2023) 100747]

  Evans, R. A., Dube, S., Lu, Y., Yates, M., Arnetorp, S., Barnes, E., Bell, S., Carty, L., Evans, K., Graham, S., Justo, N., Moss, P., Venkatesan, S., Yokota, R., Ferreira, C., McNulty, R., Taylor, S. & Quint, J. K., Sept 2024, In: The Lancet Regional Health - Europe. 44, 1 p., 101008.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File
  19 Downloads (Pure)

• Early inflammatory markers as prognostic indicators following allogeneic stem cell transplantation

  Verma, K., Croft, W., Greenwood, D., Stephens, C., Malladi, R., Nunnick, J., Zuo, J., Kinsella, F. A. M. & Moss, P., 3 Jan 2024, In: Frontiers in immunology. 14, 1332777.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Allogeneic Cells 100%
  • Stem Cell Transplantation 97%
  • Recurrence 53%
  • Proteins 34%
  • Transplantation 28%
  45 Downloads (Pure)

• Enhancement of Omicron-specific immune responses following bivalent COVID-19 booster vaccination in patients with chronic lymphocytic leukaemia

  Roberts, T., Uwenedi, G., Bruton, R., McIlroy, G., Damery, S., Sylla, P., Logan, N., Scott, S., Lau, M., Elzaidi, A., Plass, S., Mallick, S., Spencer, K., Stephens, C., Bentley, C., Pratt, G., Zuo, J., Paneesha, S., Willett, B., Moss, P., & 1 othersParry, H., 25 Jan 2024, In: Blood Cancer Journal. 14, 1, 3 p., 22.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  31 Downloads (Pure)

• Ibrutinib reversal of immune exhaustion in CLL

  Moss, P., 4 Jan 2024, In: Blood. 143, 1, p. 5-7 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Interplay in galectin expression predicts patient outcomes in a spatially restricted manner in PDAC

  Abudu, O., Nguyen, D., Millward, I., Manning, J. E., Wahid, M., Lightfoot, A., Marcon, F., Merard, R., Margielewska-Davies, S., Roberts, K., Brown, R., Powell-Brett, S., Nicol, S. M., Zayou, F., Croft, W. D., Pearce, H., Moss, P., Iqbal, A. J. & McGettrick, H. M., Mar 2024, In: Biomedicine and Pharmacotherapy. 172, 11 p., 116283.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Galectins 100%
  • Adenocarcinoma 56%
  • Fibroblasts 42%
  • Epithelial Cell Adhesion Molecule 40%
  • Epithelial Cells 31%
  39 Downloads (Pure)

• Involvement of the Gut Microbiome in the Local and Systemic Immune Response to Pancreatic Ductal Adenocarcinoma

  Halle-Smith, J. M., Pearce, H., Nicol, S., Hall, L. A., Powell-Brett, S. F., Beggs, A. D., Iqbal, T., Moss, P. & Roberts, K. J., 29 Feb 2024, In: Cancers. 16, 5, 14 p., 996.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Gastrointestinal Microbiome 100%
  • Adenocarcinoma 79%
  • Pancreatic Neoplasms 47%
  • Immune System 40%
  • Neoplasms 24%
  19 Downloads (Pure)

• PD-1 expression contributes to functional impairment of NK cells in patients with B-CLL

  Farhat, M., Croft, W., Parry, H. M., Verma, K., Kinsella, F. A. M., Xu, J., Bone, D., McSkeane, T., Paneesha, S., Pratt, G., Moss, P. & Zuo, J., 9 May 2024, (E-pub ahead of print) In: Leukemia. 38, 8, p. 1813-1817 5 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  47 Downloads (Pure)

• Safety outcomes following COVID-19 vaccination and infection in 5.1 million children in England

  Copland, E., Patone, M., Saatci, D., Handunnetthi, L., Hirst, J., Hunt, D. P. J., Mills, N. L., Moss, P., Sheikh, A., Coupland, C. A. C., Harnden, A., Robertson, C. & Hippisley-Cox, J., 27 May 2024, In: Nature Communications. 15, 1, 3822.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • England 100%
  • infectious diseases 86%
  • safety 65%
  • Safety 58%
  • Vaccination 54%
  23 Downloads (Pure)
• 2023

  Assessing neutrophil-derived ROS production at the bedside: a potential prognostic tool in severe COVID-19 cases

  Dündar, N. B., Sarphie, D., Yüce, K., Gaygısız, Ü., Kaskatı, O. T., Türkoğlu, M., Bıkmaz, G. A., Karabıyık, L., Çağlar, K., Bozdayı, G., Mian, R., Moss, P. & İlhan, M. N., 6 Oct 2023, In: Intensive Care Medicine Experimental. 11, 1, 12 p., 69.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Reactive Oxygen Species 100%
  • Neutrophils 97%
  • Leukocytes 76%
  • Neutrophil Activation 17%
  • Mortality 13%
  34 Downloads (Pure)

• Clinical Effectiveness of SARS-CoV-2 Booster Vaccine Against Omicron Infection in Residents and Staff of Long-term Care Facilities: A Prospective Cohort Study (VIVALDI)

  Stirrup, O., Shrotri, M., Adams, N. L., Krutikov, M., Nacer-Laidi, H., Azmi, B., Palmer, T., Fuller, C., Irwin-Singer, A., Baynton, V., Tut, G., Moss, P., Hayward, A., Copas, A. & Shallcross, L., Jan 2023, In: Open Forum Infectious Diseases. 10, 1, 10 p., ofac694.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Long-Term Care 83%
  • Vaccines 58%
  • Cohort Studies 52%
  34 Downloads (Pure)

• Corrigendum: SARS-CoV-2 Omicron variants: burden of disease, impact on vaccine effectiveness and need for variant-adapted vaccines

  Pather, S., Madhi, S. A., Cowling, B. J., Moss, P., Kamil, J. P., Ciesek, S., Muik, A. & Türeci, Ö., 12 Jun 2023, In: Frontiers in immunology. 14, 2 p., 1232965.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Bryophyta 53%
  • Vaccines 50%
  48 Downloads (Pure)

• Defective T‐cell response to COVID‐19 vaccination in acute myeloid leukaemia and myelodysplastic syndromes

  Loke, J., Upasani, V., Gaskell, C., Fox, S., Fletcher, R., Thomas, C., Hopkins, L., Kumari, A., Tang, T., Yafai, E., Boucher, R., Homer, V., Toth, A., Chan, Y. L. T., Randall, K., Rider, T., O'nions, J., Drew, V., Pillai, A., Dungarwalla, M., & 14 othersMurray, D., Khan, A., Wandroo, F., Moore, S., Krishnamurthy, P., Huang, Y. J., Knapper, S., Byrne, J., Zhao, R., Craddock, C., Parry, H., Moss, P., Stanworth, S. J. & Lowe, D. M., Aug 2023, In: British Journal of Haematology. 202, 3, p. 498-503 6 p.

  Research output: Contribution to journal › Article › peer-review

  • GATA2 Deficiency 100%
  • Vaccination 57%
  • T-Lymphocytes 22%
  • Acute Myeloid Leukemia 17%
  • Epidemiology 14%

• Early evaluation of the safety, reactogenicity, and immune response after a single dose of modified vaccinia Ankara-Bavaria Nordic vaccine against mpox in children: a national outbreak response

  Ladhani, S. N., Dowell, A. C., Jones, S., Hicks, B., Rowe, C., Begum, J., Wailblinger, D., Wright, J., Owens, S., Pickering, A., Shilltoe, B., McMaster, P., Whittaker, E., Zuo, J., Powell, A., Amirthalingam, G., Mandal, S., Lopez-Bernal, J., Ramsay, M. E., Kissane, N., & 7 othersBell, M., Watson, H., Ho, D., Hallis, B., Otter, A., Moss, P. & Cohen, J., Sept 2023, In: The Lancet Infectious Diseases. 23, 9, p. 1042-1050 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vaccinia 100%
  • Disease Outbreaks 65%
  • Vaccines 55%
  • Vaccination 44%
  • Safety 43%
  26 Downloads (Pure)

• Early expression of CD94 and loss of CD96 on CD8+ T cells after allogeneic SCT is predictive of subsequent relapse and survival

  Verma, K., Croft, W., Pearce, H., Zuo, J., Stephens, C., Nunnick, J., Kinsella, F., Malladi, R. & Moss, P., Feb 2023, In: Haematologica. 108, 2, p. 433-443 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • T-Lymphocytes 100%
  • Recurrence 92%
  • Survival 89%
  • NK Cell Lectin-Like Receptor Subfamily C 39%
  • Homologous Transplantation 26%
  30 Downloads (Pure)

• Effectiveness of successive booster vaccine doses against SARS-CoV-2 related mortality in residents of long-term care facilities in the VIVALDI study

  Stirrup, O., Shrotri, M., Adams, N. L., Krutikov, M., Azmi, B., Monakhov, I., Tut, G., Moss, P., Hayward, A., Copas, A. & Shallcross, L., Aug 2023, In: Age and Ageing. 52, 8, 6 p., afad141.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Long-Term Care 73%
  • Vaccination 54%
  • Vaccines 50%
  • Mortality 34%
  10 Downloads (Pure)

• Ethnic differences in cellular and humoral immune responses to SARS-CoV-2 vaccination in UK healthcare workers: a cross-sectional analysis

  Martin, C. A., Nazareth, J., Jarkhi, A., Pan, D., Das, M., Logan, N., Scott, S., Bryant, L., Abeywickrama, N., Adeoye, O., Ahmed, A., Asif, A., Bandi, S., George, N., Gohar, M., Gray, L. J., Kaszuba, R., Mangwani, J., Martin, M., Moorthy, A., & 13 othersRenals, V., Teece, L., Vail, D., Khunti, K., Moss, P., Tattersall, A., Hallis, B., Otter, A. D., Rowe, C., Willett, B. J., Haldar, P., Cooper, A. & Pareek, M., 4 Apr 2023, In: EClinicalMedicine. 58, 16 p., 101926.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Humoral Immunity 70%
  • Cellular Immunity 65%
  • Health Personnel 58%
  • Vaccination 54%
  48 Downloads (Pure)

• Immunological imprinting of humoral immunity to SARS-CoV-2 in children

  Dowell, A. C., Lancaster, T., Bruton, R., Ireland, G., Bentley, C., Sylla, P., Zuo, J., Scott, S., Jadir, A., Begum, J., Roberts, T., Stephens, C., Ditta, S., Shepherdson, R., Powell, A. A., Brent, A. J., Brent, B., Baawuah, F., Okike, I., Beckmann, J., & 10 othersAhmad, S., Aiano, F., Garstang, J., Ramsay, M. E., Azad, R., Waiblinger, D., Willett, B., Wright, J., Ladhani, S. N. & Moss, P., 29 Jun 2023, In: Nature Communications. 14, 1, 9 p., 3845.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • infectious diseases 85%
  • immunity 78%
  • Humoral Immunity 70%
  • Neutralization 68%
  31 Downloads (Pure)

• Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study

  Evans, R. A., Dube, S., Lu, Y., Yates, M., Arnetorp, S., Barnes, E., Bell, S., Carty, L., Evans, K., Graham, S., Justo, N., Moss, P., Venkatesan, S., Yokota, R., Ferreira, C., McNulty, R., Taylor, S. & Quint, J. K., 13 Oct 2023, (E-pub ahead of print) In: The Lancet Regional Health - Europe. 16 p., 100747.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hospitalization 100%
  • Intensive Care Units 84%
  • Incidence 82%
  • Confidence Intervals 80%
  • Population 66%
  75 Downloads (Pure)

• Nasal mucosal IgA levels against SARS-CoV-2 and seasonal coronaviruses are low in children but boosted by reinfection

  Dowell, A. C., Tut, G., Begum, J., Bruton, R., Bentley, C., Butler, M., Uwenedi, G., Zuo, J., Powell, A. A., Brent, A. J., Brent, B., Baawuah, F., Okike, I., Beckmann, J., Ahmad, S., Aiano, F., Garstang, J., Ramsay, M. E., Moss, P. & Ladhani, S. N., Nov 2023, In: Journal of Infection. 87, 5, p. 403-412 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Coronavirus 85%
  • Immunoglobulin A 63%
  • Nose 54%
  • Child 29%
  60 Downloads (Pure)

• Nucleocapsid-specific antibodies as a correlate of protection against SARS-CoV-2 reinfection in children

  sKIDS Investigation team, Sept 2023, In: Journal of Infection. 87, 3, p. 267-269 3 p.

  Research output: Contribution to journal › Letter › peer-review

• Pancreatic Exocrine Insufficiency and the Gut Microbiome in Pancreatic Cancer: A Target for Future Diagnostic Tests and Therapies?

  Halle-Smith, J. M., Hall, L. A., Powell-Brett, S. F., Merali, N., Frampton, A. E., Beggs, A. D., Moss, P. & Roberts, K. J., 25 Oct 2023, In: Cancers. 15, 21, 15 p., 5140.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Exocrine Pancreatic Insufficiency 100%
  • Gastrointestinal Microbiome 72%
  • Pancreatic Neoplasms 69%
  • Routine Diagnostic Tests 69%
  • Enzyme Replacement Therapy 64%
  125 Downloads (Pure)

• Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia

  Barber, V. S., Peckham, N., Duley, L., Francis, A., Abhishek, A., Moss, P., Cook, J. A. & Parry, H. M., 28 Sept 2023, In: BMJ open. 13, 9, e077946.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Agammaglobulinaemia Tyrosine Kinase 99%
  • B-Cell Chronic Lymphocytic Leukemia 72%
  • Vaccination 54%
  • Randomized Controlled Trials 45%
  28 Downloads (Pure)

• Robust generation of neutralising antibodies against Omicron variants following bivalent mRNA booster vaccine in elderly people aged >80 years

  Parry, H., Moss, P., Uwenedi, G., Roberts, T., Sylla, P., Cook, J., Elzaidi, A., Lau, M., Drury, T., Bray, A., Mallick, S., Spencer, K., Bentley, C., Mcilroy, G., Scott, S., Logan, N., Zuo, J., Willett, B. & Moss, P., 1 Sept 2023, (E-pub ahead of print) In: Journal of Infection.

  Research output: Contribution to journal › Letter › peer-review

• SARS-CoV-2 Omicron variants: burden of disease, impact on vaccine effectiveness and need for variant-adapted vaccines

  Pather, S., Madhi, S. A., Cowling, B. J., Moss, P., Kamil, J. P., Ciesek, S., Muik, A. & Türeci, Ö., 23 May 2023, In: Frontiers in immunology. 14, 13 p., 1130539.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Vaccines 58%
  • Immunity 21%
  • Infections 12%
  66 Downloads (Pure)

• Spatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinoma

  Croft, W., Pearce, H., Margielewska-Davies, S., Lim, L., Nicol, S. M., Zayou, F., Blakeway, D., Marcon, F., Powell-Brett, S., Mahon, B., Merard, R., Zuo, J., Middleton, G., Roberts, K., Brown, R. M., Moss, P. & Ng, T., 21 Jul 2023, In: eLife. 12, 19 p., 86125.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Heterogeneity 100%
  • Transcriptome 99%
  • Adenocarcinoma 84%
  • Fibroblasts 80%
  • Cancer-Associated Fibroblasts 75%
  33 Downloads (Pure)

• Spatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinoma

  Croft, W., Pearce, H., Margielewska-Davies, S., Lim, L., Nicol, S. M., Zayou, F., Blakeway, D., Marcon, F., Powell-Brett, S., Mahon, B., Merard, R., Zuo, J., Middleton, G., Roberts, K., Brown, R. M. & Moss, P., 21 Jan 2023, bioRxiv.

  Research output: Working paper/Preprint › Preprint

  • Transcriptome 100%
  • Adenocarcinoma 85%
  • Fibroblasts 80%
  • Cancer-Associated Fibroblasts 76%
  • Neoplasms 35%

• Strong peak immunogenicity but rapid antibody waning following third vaccine dose in older residents of care homes

  Crick COVID Immunity Pipeline, 20 Jan 2023, In: Nature Aging. 3, 1, p. 93-104 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Home Care Services 100%
  • Vaccines 71%
  • Vaccination 57%
  • Antibodies 52%
  • Coronavirus 29%
  27 Downloads (Pure)

• The impact of patient and public involvement on COVID-19 immunology research: experiences from the UK Coronavirus Immunology Consortium

  Aquino, E. N., Moss, P., Hafeez, M., Jasper, R., Kelly, T., Laidlaw, L. & Wilkes, V., 22 May 2023, In: Research Involvement and Engagement. 9, 1, 13 p., 34.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

  • Coronavirus 100%
  • Patient Participation 90%
  • Allergy and Immunology 84%
  • SARS Virus 10%
  • Research Personnel 10%
  42 Downloads (Pure)

• Tissue-resident memory T cells in pancreatic ductal adenocarcinoma co-express PD-1 and TIGIT and functional inhibition is reversible by dual antibody blockade

  Pearce, H., Croft, W., Nicol, S., Margielewska-Davies, S., Powell, R., Cornall, R., Davis, S., Marcon, F., Pugh, M., Fennell, E., Powell-Brett, S., Mahon, B., Brown, R. M., Middleton, G., Roberts, K. & Moss, P., 3 Apr 2023, In: Cancer immunology research. 11, 4, p. 435–449 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Adenocarcinoma 100%
  • T-Lymphocytes 78%
  • Antibodies 70%
  • Ligands 33%
  • Tumor Microenvironment 33%
  43 Downloads (Pure)
• 2022

  Antibody and cellular immune responses following dual COVID-19 vaccination within infection-naive residents of long-term care facilities: an observational cohort study

  Tut, G., Lancaster, T., Sylla, P., Butler, M. S., Kaur, N., Spalkova, E., Bentley, C., Amin, U., Jadir, A., Hulme, S., Ayodele, M., Bone, D., Tut, E., Moss, P., Krutikov, M., Giddings, R., Shrotri, M., Azmi, B., Fuller, C., Baynton, V., & 5 othersIrwin-Singer, A., Hayward, A., Copas, A., Shallcross, L. & Moss, P., 4 Jul 2022, In: The Lancet Healthy Longevity. 3, 7, p. e461-e469

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Long-Term Care 100%
  • Cellular Immunity 89%
  • Vaccination 74%
  • Observational Studies 71%
  • Cohort Studies 63%
  108 Downloads (Pure)

• Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection

  Dowell, A. C., Butler, M. S., Jinks, E., Tut, G., Lancaster, T., Sylla, P., Begum, J., Bruton, R., Pearce, H., Verma, K., Logan, N., Tyson, G., Spalkova, E., Margielewska-Davies, S., Taylor, G. S., Syrimi, E., Baawuah, F., Beckmann, J., Okike, I. O., Ahmad, S., & 24 othersGarstang, J., Brent, A. J., Brent, B., Ireland, G., Aiano, F., Amin-Chowdhury, Z., Jones, S., Borrow, R., Linley, E., Wright, J., Azad, R., Waiblinger, D., Davis, C., Thomson, E. C., Palmarini, M., Willett, B. J., Barclay, W. S., Poh, J., Amirthalingam, G., Brown, K. E., Ramsay, M. E., Zuo, J., Moss, P. & Ladhani, S., Jan 2022, In: Nature Immunology. 23, 1, p. 40-49 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Infections 32%
  • Child 29%
  • Coronavirus 18%
  • Antibody Formation 13%
  9 Citations (Scopus)

  59 Downloads (Pure)

• CMV reactivation initiates long-term expansion and differentiation of the NK cell repertoire

  Hassan, N., Eldershaw, S., Stephens, C., Kinsella, F., Craddock, C., Malladi, R., Zuo, J. & Moss, P., 1 Dec 2022, In: Frontiers in immunology. 13, 14 p., 935949.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Natural Killer Cells 100%
  • Cytomegalovirus Infections 19%
  • Stem Cell Transplantation 18%
  • Drive 18%
  • Infection Control 18%
  53 Downloads (Pure)

• COVID-19 vaccines elicit robust cellular immunity and clinical protection in chronic lymphocytic leukemia

  Parry, H., Bruton, R., Roberts, T., Mcilroy, G., Damery, S., Sylla, P., Dowell, A. C., Tut, G., Lancaster, T., Bone, D., Willett, B., Logan, N., Scott, S., Hulme, S., Jadir, A., Amin, U., Nicol, S., Stephens, C., Faustini, S., Al-taei, S., & 9 othersRichter, A., Blakeway, D., Verma, K., Margielewska-davies, S., Pearce, H., Pratt, G., Zuo, J., Paneesha, S. & Moss, P., 13 Jun 2022, In: Cancer Cell. 40, 6, p. 584-586 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  71 Downloads (Pure)

• Current and Future Immunotherapy-Based Treatments for Oesophageal Cancers

  To, N., Evans, R. P. T., Pearce, H., Kamarajah, S. K., Moss, P. & Griffiths, E. A., 24 Jun 2022, In: Cancers. 14, 13, 3104.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Esophageal Neoplasms 100%
  • Immunotherapy 86%
  • Immune System 38%
  • Combination Drug Therapy 16%
  • Therapeutics 15%
  64 Downloads (Pure)

• Cytomegalovirus infection is a risk factor for venous thromboembolism in ANCA-associated vasculitis

  King, C., Patel, R., Mendoza, C., Walker, J. K., Wu, E. Y., Moss, P., Morgan, M. D., Bunch, D. OD., Harper, L. & Chanouzas, D., 10 Aug 2022, In: Arthritis Research & Therapy. 24, 1, 9 p., 192.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cytomegalovirus Infections 100%
  • Venous Thromboembolism 97%
  • Vasculitis 93%
  • Cytoplasm 74%
  • Neutrophils 70%
  48 Downloads (Pure)

• Extended interval BNT162b2 vaccination enhances peak antibody generation

  Parry, H., Moss, P., Stephens, C., Bentley, C., Brown, K., Amirthalingam, G., Hallis, B., Otter, A., Zuo, J. & Moss, P., 27 Jan 2022, In: NPJ vaccines. 7, 1, 14.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vaccination 100%
  • Vaccines 93%
  • Antibody Formation 74%
  • Antibodies 69%
  • Adaptive Immunity 42%
  68 Downloads (Pure)

• High generation of reactive oxygen species from neutrophils in patients with severe COVID-19

  Veenith, T., Martin, H., Le Breuilly, M., Whitehouse, T., Gao-Smith, F., Duggal, N., Lord, J. M., Mian, R., Sarphie, D. & Moss, P., 21 Jun 2022, In: Scientific Reports. 12, 1, 9 p., 10484.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Reactive Oxygen Species 100%
  • Neutrophils 97%
  • Sepsis 43%
  • Acute Disease 19%
  • Infections 17%
  27 Downloads (Pure)

• Impaired neutralisation of SARS-CoV-2 delta variant in vaccinated patients with B cell chronic lymphocytic leukaemia

  Parry, H., McIlroy, G., Moss, P., Damery, S., Tyson, G., Logan, N., Davis, C., Willett, B., Zuo, J., Ali, M., Kaur, M., Stephens, C., Brant, D., Otter, A., McSkeane, T., Rolfe, H., Faustini, S., Richter, A., Lee, S., Wandroo, F., & 4 othersShafeek, S., Pratt, G., Paneesha, S. & Moss, P., Dec 2022, In: Journal of Hematology and Oncology. 15, 1, 12 p., 3.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • B-Cell Chronic Lymphocytic Leukemia 72%
  • Antibody Formation 54%
  • Vaccines 22%
  • Vaccination 18%
  70 Downloads (Pure)

• Machine learning of COVID-19 clinical data identifies population structures with therapeutic potential

  Greenwood, D., Taverner, T., Adderley, N. J., Price, M., Gokhale, K., Sainsbury, C., Gallier, S., Welch, C., Sapey, E., Murray, D., Fanning, H., Ball, S., Nirantharakumar, K., Croft, W. & Moss, P., 15 Jul 2022, In: iScience. 25, 7, 104480.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Machine Learning 100%
  • Datasets 35%
  • Population 34%
  • Pandemics 23%
  • Cluster Analysis 19%
  67 Downloads (Pure)

• mRNA or ChAd0x1 COVID-19 Vaccination of Adolescents Induces Robust Antibody and Cellular Responses With Continued Recognition of Omicron Following mRNA-1273

  Dowell, A. C., Powell, A. A., Davis, C., Scott, S., Logan, N., Willett, B. J., Bruton, R., Ayodele, M., Jinks, E., Gunn, J., Spalkova, E., Sylla, P., Nicol, S. M., Zuo, J., Ireland, G., Okike, I., Baawuah, F., Beckmann, J., Ahmad, S., Garstang, J., & 18 othersBrent, A. J., Brent, B., White, M., Collins, A., Davis, F., Lim, M., Cohen, J., Kenny, J., Linley, E., Poh, J., Amirthalingam, G., Brown, K., Ramsay, M. E., Azad, R., Wright, J., Waiblinger, D., Moss, P. & Ladhani, S. N., 2 Jun 2022, In: Frontiers in immunology. 13, 882515.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Antibody Formation 100%
  • Vaccination 89%
  • Messenger RNA 63%
  • Vaccines 33%
  • T-Lymphocytes 27%
  38 Downloads (Pure)

• Mutations in SARS-CoV-2 spike protein impair epitope-specific CD4⁺ T cell recognition

  Tye, E., Jinks, E., Haigh, T., Kaul, B., Patel, P., Parry, H., Newby, M., Crispin, M., Kaur, N., Moss, P., Drennan, S., Taylor, G. & Long, H., 1 Dec 2022, In: Nature Immunology. 23, p. 1726–1734 23 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Epitopes 58%
  • T-Lymphocytes 41%
  • Mutation 37%
  • Proteins 24%
  42 Downloads (Pure)

• Robust SARS-CoV-2-specific and heterologous immune responses in vaccine-naïve residents of long-term care facilities who survive natural infection

  Tut, G., Lancaster, T., Butler, M. S., Sylla, P., Spalkova, E., Bone, D., Kaur, N., Bentley, C., Amin, U., Jadir, A. T., Hulme, S., Ayodel, M., Dowell, A. C., Pearce, H., Zuo, J., Margielewska-Davies, S., Verma, K., Nicol, S., Begum, J., Jinks, E., & 12 othersTut, E., Moss, P., Krutikov, M., Shrotri, M., Giddings, R., Azmi, B., Fuller, C., Irwin-Singer, A., Hayward, A., Copas, A., Shallcross, L. & Moss, P., Jun 2022, In: Nature Aging. 2, 6, p. 536-547 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Long-Term Care 83%
  • Vaccines 58%
  • Humoral Immunity 40%
  22 Downloads (Pure)

• SARS-CoV-2 vaccine responses following CD20-depletion treatment in patients with haematological and rheumatological disease: a West Midlands Research Consortium study

  Shields, A. M., Venkatachalam, S., Shafeek, S., Paneesha, S., Ford, M., Sheeran, T., Kelly, M., Qureshi, I., Salhan, B., Karim, F., De Silva, N., Stones, J., Lee, S., Khawaja, J., Kaudlay, P. K., Whitmill, R., Kakepoto, G. N., Parry, H. M., Moss, P., Faustini, S. E., & 3 othersRichter, A. G., Drayson, M. T. & Basu, S., 28 Jan 2022, In: Clinical and Experimental Immunology. 207, 1, p. 3-10 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Hematologic Diseases 79%
  • Vaccines 50%
  • B-Lymphocytes 46%
  • Vaccination 12%
  47 Downloads (Pure)

• The single cell transcriptional landscape of esophageal adenocarcinoma and its modulation by neoadjuvant chemotherapy

  Croft, W., Evans, R. P. T., Pearce, H., Elshafie, M., Griffiths, E. A. & Moss, P., 17 Oct 2022, In: Molecular Cancer. 21, 1, 17 p., 200.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Adenocarcinoma 100%
  • Drug Therapy 75%
  • Cancer-Associated Fibroblasts 59%
  • Population 49%
  • Stromal Cells 42%
  92 Downloads (Pure)

• Vaccine subtype and dose interval determine immunogenicity of primary series COVID-19 vaccines in older people

  Parry, H., Bruton, R., Ayodele, R., Sylla, P., McIlroy, G., Logan, N., Scott, S., Nicol, S., Verma, K., Stephens, C., Willett, B., Zuo, J. & Moss, P., 20 Sept 2022, In: Cell Reports Medicine. 3, 9, 100739.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vaccines 100%
  • Vaccine Immunogenicity 93%
  • Antibodies 73%
  • Humoral Immunity 69%
  • Cellular Immunity 64%
  52 Downloads (Pure)