Personal profile
Biography
Dr Nikolaos Batis is an Assistant Professor of Translational Pharmacology in Biomedical Sciences and Head of Global Engagement for the School of Infection, Immunity and Inflammation at the University of Birmingham’s College of Medicine and Health.
He obtained his PhD in Pharmacology from the University of Birmingham, following a BMedSc (Hons) in Medical Science (Pharmacology). His doctoral work focused on the allosteric pharmacology of the 5-HT3 receptor, laying the foundation for a career spanning receptor biology, drug discovery, translational oncology and biomarker science. His early research training was shaped within pharmacology and neurobiology groups at Birmingham, before progressing into translational cancer research through clinical-academic collaborations at the Queen Elizabeth Hospital Birmingham.
Dr Batis is a translational pharmacologist working at the interface of academic drug discovery, biomarker development and clinical implementation. His research programme focuses on oncology and precision medicine, spanning drug repurposing, rational combination therapies, PK/PD-informed preclinical strategy, and the development of prognostic and predictive biomarkers, including circulating tumour DNA and lipidomic approaches. Leveraging patient-derived tissues and advanced pharmacological methodologies, his work interrogates lipid metabolism, receptor signalling and mitochondrial function to identify clinically actionable vulnerabilities in cancer.
He has worked closely with multidisciplinary clinical and translational teams including oncologists, surgeons, pathologists, pharmacologists, bioinformaticians and industry partners. His collaborations span academic colleagues across the University of Birmingham, the Queen Elizabeth Hospital Birmingham, the Phenome Centre Birmingham, international academic institutions, and pharmaceutical and biotechnology companies. Through these partnerships, he has contributed to major multinational clinical and translational studies published in leading journals, and his work has informed risk stratification strategies and biomarker-led approaches in head and neck oncology.
Alongside his research, Dr Batis leads the integration of business, innovation and entrepreneurship within biomedical education. He has developed and scaled enterprise-focused curricula that connect biomedical science with real-world regulatory, investment and commercial pathways. He is the founder of the Biomedical Training Incubator, a structured programme linking discovery science, industry mentorship and enterprise skills development to enhance research readiness and employability. His educational leadership bridges academic science, clinical translation and commercial implementation.
In his role as Head of Global Engagement, he provides strategic direction for international partnerships, academic diplomacy, student mobility and global reputation initiatives. He oversees collaborative programmes across Europe and the Middle East, including engagement with the University of Birmingham Dubai, and has led cross-institutional research and education initiatives designed to strengthen international translational health networks.
Dr Batis has extensive experience leading multidisciplinary translational research teams and mentoring early-career researchers. He has served on institutional committees relating to research governance and ethics, contributing to the development of robust research integrity practices. His work integrates scientific excellence, industry relevance and global collaboration to advance impactful biomedical research, innovation and education.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Circulating tumour DNA detects somatic variants contributing to spatial and temporal intratumural heterogeneity in head and neck squamous cell carcinoma
Payne, K. F. B., Brotherwood, P., Suriyanarayanan, H., Brooks, J. M., Batis, N., Beggs, A. D., Gendoo, D. M. A., Mehanna, H. & Nankivell, P., 23 Apr 2024, In: Frontiers in Oncology. 14, 11 p., 1374816.Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Downloads (Pure) -
Developing and validating a multivariable prognostic-predictive classifier for treatment escalation of oropharyngeal squamous cell carcinoma: the PREDICTR-OPC study
Mehanna, H., Rapozo, D., Zeidler, S. V. V., Harrington, K., Winter, S., Hartley, A., Nankivell, P., Schache, A., Sloan, P., Odell, E., Thavaraj, S., Hunter, K., Shah, K., Thomas, G., Long, A., Amel-Kashipaz, R., Brown, R., Conn, B., Hall, G. & Matthews, P. & 15 others, , 17 Jan 2024, In: Clinical Cancer Research. 30, 2, p. 356–367 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Downloads (Pure) -
TNM 8 staging system beyond p16: Double HPV/p16 status is superior to p16 alone in predicting outcome in oropharyngeal squamous cell carcinoma
HNCIG-EPIC group, Nov 2024, In: European Journal of Cancer. 211, 114329.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Downloads (Pure) -
Feasibility of mass cytometry proteomic characterisation of circulating tumour cells in head and neck squamous cell carcinoma for deep phenotyping
Payne, K., Brooks, J., Batis, N., Khan, N., El-Asrag, M., Nankivell, P., Mehanna, H. & Taylor, G., 9 Nov 2023, In: British Journal of Cancer. 129, 10, p. 1590-1598 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile88 Downloads (Pure) -
Lead Time to Recurrence After Posttreatment Plasma and Saliva HPV DNA Testing in Patients With Low-Risk HPV Oropharynx Cancer
Califano, J., Yousef, A., Mostafa, H., Valsamakis, A., Zhang, X., Batis, N., Varghese, C., Parish, J., Forman, M., Jarrett, J., Messer, K. & Mehanna, H., 1 Sept 2023, In: JAMA Otolaryngology - Head and Neck Surgery. 149, 9, p. 812-819 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile95 Downloads (Pure)
Projects
- 3 Finished
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Wellcome TDF: Developing and validating a hypoxia-immune treatment response classifier for oropharyngeal cancer
Batis, N. (Co-Investigator), Brooks, J. (Co-Investigator) & Mehanna, H. (Principal Investigator)
7/02/22 → 6/08/22
Project: Research
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Targeting the 3q amplification
Mehanna, H. (Co-Investigator), Batis, N. (Co-Investigator) & Morris, J. (Principal Investigator)
30/09/19 → 31/12/24
Project: Research
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CRUK/13/026 CompARE Collect: Prospective biological sample collection from patients with intermediate and high risk oropharyngeal cancer recruited to comPARE randomised controlled trial
Batis, N. (Co-Investigator), Nankivell, P. (Co-Investigator), Spruce, R. (Co-Investigator) & Mehanna, H. (Principal Investigator)
1/08/17 → 31/12/25
Project: Research
Activities
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Clinical Cancer Research (Journal)
Batis, N. (Peer reviewer)
2018 → …Activity: Publication peer-review and editorial work › Publication peer-review
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The University of Birmingham (Organisational unit)
Batis, N. (Assessor)
2018 → …Activity: Membership › Internal role
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American Journal of Pharmacology and Toxicology (Journal)
Batis, N. (Editor)
2017 → …Activity: Publication peer-review and editorial work › Editorial board of a journal
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NIHR (External organisation)
Batis, N. (Advisor)
2017 → …Activity: Membership › Membership of working group or committee
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British Pharmacological Society Winter Meeting
Batis, N. (Contributor)
13 Dec 2016 → 15 Dec 2016Activity: Academic and Industrial events › Conference, workshop or symposium
Prizes
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PERCAT Postdoctoral Excellence Award in Teaching
Batis, N. (Recipient), 2017
Prize: Prize (including medals and awards)