Nik Hodges is interested in the mechanisms of genetic toxicology, cellular oxidative stress and repair of oxidative DNA damage, and his lab was the first to identify that the variant form of the repair protein OGG1 is repair-deficient under conditions of oxidative stress, which could have important consequences for individual susceptibility to cancer.
In particular, Dr Hodges’s team is interested in the cellular consequences of pertubation of redox homeostasis both by chemical and biological mechanisms, including:
OGG1 (DNA repair protein)
Cellular oxidative stress
Research activity per year
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