Mohammed Jamshad

Research output

Research output per year 2011 2017 2019 2020 2020

• 22 Article
• 1 Working paper

Research output per year

Research output per year

Search results

• A method for detergent-free isolation of membrane protein with its local lipid environment

  Lee, S. C., Knowles, T. J., Postis, V. L. G., Jamshad, M., Parslow, R. A., Lin, Y., Goldman, A., Sridhar, P., Overduin, M., Muench, S. P. & Dafforn, T. R., 1 Jul 2016, In: Nature protocols. 11, 7, p. 1149–1162 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Detergents 100%
  • Membrane Proteins 79%
  • Lipid 65%
  • Lipids 62%
  • Environment 54%
  175 Citations (Scopus)

  603 Downloads (Pure)

• A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81

  Grove, J., Hu, K., Farquhar, M. J., Goodall, M., Walker, L., Jamshad, M., Drummer, H. E., Bill, R. M., Balfe, P. & McKeating, J. A., 7 Sept 2017, In: Wellcome Open Research. 2

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tetraspanins 100%
  • Epitopes 58%
  • Monoclonal Antibodies 50%
  • Hepacivirus 42%
  • Electron Scanning Microscopy 22%
  8 Citations (Scopus)

  141 Downloads (Pure)

• AscA (YecA) is a molecular chaperone involved in Sec-dependent protein translocation in Escherichia coli

  Cranford-Smith, T., Wynne, M., Carter, C., Jiang, C., Jamshad, M., Milner, M., Djouider, Y., Hutchinson, E., Lund, P., Henderson, I. & Huber, D., 22 Jul 2020, In: bioRkiv.

  Research output: Contribution to journal › Article

• Detergent-free purification of ABC (ATP-binding-cassette) transporters

  Gulati, S., Jamshad, M., Knowles, T., Morrison, K. A., Downing, R., Cant, N., Collins, R., Koenderink, J. B., Ford, R. C., Overduin, M., Kerr, I. D. & Rothnie, A. J., Jul 2014, In: Biochemical Journal. 461, 2, p. 269-278 12 p.

  Research output: Contribution to journal › Article › peer-review

  • ATP-Binding Cassette Transporters 100%
  • Detergents 87%
  • Detergent 65%
  • Lipid 57%
  • Purification 56%
  105 Citations (Scopus)

• Disruption of yeast cells to isolate recombinant proteins.

  Jamshad, M. & Darby, RA., 1 Jan 2012, In: Methods in molecular biology. 866, p. 237-46 10 p.

  Research output: Contribution to journal › Article

  • Recombinant Proteins 100%
  • Yeasts 82%
  • Biocompatible Materials 51%
  • Proteins 37%
  • Membranes 30%
  2 Citations (Scopus)

• Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system

  Hughes, G., Hall, S., Laxton, C., Sridhar, P., Mahadi, A., Hatton, C., Piggot, T., Wotherspoon, P., Leney, A., Ward, D., Jamshad, M., Spana, V., Cadby, I., Harding, C., Isom, G., Bryant, J., Parr, R., Yakub, Y., Jeeves, M., Huber, D., & 4 othersHenderson, I., Clifton, L., Lovering, A. & Knowles, T., Oct 2019, In: Nature Microbiology. 4, 10, p. 1692–1705 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Phospholipids 100%
  • Membranes 66%
  • Periplasmic Proteins 28%
  • Periplasm 24%
  • Adenosine Triphosphatases 18%
  30 Citations (Scopus)

  352 Downloads (Pure)

• GPCR-styrene maleic acid lipid particles (GPCR-SMALPs): their nature and potential

  Wheatley, M., Charlton, J., Jamshad, M., Routledge, S. J., Bailey, S., La-Borde, P. J., Azam, M. T., Logan, R. T., Bill, R. M., Dafforn, T. & Poyner, D. R., 11 Apr 2016, In: Biochemical Society Transactions. 44, 2, p. 619-623 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • maleic acid 100%
  • Styrene 98%
  • Maleic Acid 83%
  • Detergents 73%
  • G-Protein-Coupled Receptors 70%
  21 Citations (Scopus)

  365 Downloads (Pure)

• G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent

  Jamshad, M., Charlton, J., Lin, Y-P., Routledge, S. J., Bawa, Z., Knowles, T. J., Overduin, M., Dekker, N., Dafforn, T., Bill, R. M., Poyner, D. R. & Wheatley, M., 1 Apr 2015, In: Bioscience Reports. 35, 2, e00188.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Detergents 100%
  • G-Protein-Coupled Receptors 96%
  • Solubilization 92%
  • Detergent 89%
  • Lipid 65%
  89 Citations (Scopus)

  176 Downloads (Pure)

• Iron is a ligand of SecA-like metal-binding domains in vivo

  Cranford-Smith, T., Jamshad, M., Jeeves, M., Chandler, R., Yule, J., Robinson, A., Alam, F., Dunne, K., Aponte Angarita, E., Alanazi, M., Carter, C., Henderson, I., Lovett, J., Winn, P., Knowles, T. & Huber, D., 22 May 2020, In: Journal of Biological Chemistry. 295, 21, p. 7516-7528 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Metals 100%
  • Iron 96%
  • Sodium Azide 88%
  • Ligands 81%
  • Azide 70%
  1 Citation (Scopus)

  140 Downloads (Pure)

• Isomerization of BRCA1-BARD1 promotes replication fork protection

  Daza-Martin, M., Starowicz, K., Jamshad, M., Tye, S., Ronson, G. E., MacKay, H. L., Chauhan, A. S., Walker, A. K., Stone, H. R., Beesley, J. F. J., Coles, J. L., Garvin, A. J., Stewart, G. S., McCorvie, T. J., Zhang, X., Densham, R. M. & Morris, J. R., 25 Jul 2019, In: Nature. 571, 7766, p. 521-527

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Homologous Recombination 100%
  • Fanconi Anemia Complementation Group Proteins 73%
  • Peptidylprolyl Isomerase 63%
  • Phosphorylation 30%
  • Genome 30%
  31 Citations (Scopus)

  688 Downloads (Pure)

• Ligand-induced conformational changes in a SMALP-encapsulated GPCR.

  Routledge, S. J., Jamshad, M., Little, H. A., Lin, Y., Simms, J., Thakker, A., Spickett, C. M., Bill, R. M., Dafforn, T. R., Poyner, D. R. & Wheatley, M., 1 Jun 2020, In: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1862, 6, 11 p., 183235.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • maleic acid 100%
  • ZM 241385 99%
  • Styrene 98%
  • Purinergic P1 Receptors 87%
  • Maleic Acid 83%
  7 Citations (Scopus)

  193 Downloads (Pure)

• MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis

  Isom, G. L., Davies, N. J., Chong, Z-S., Bryant, J. A., Jamshad, M., Sharif, M., Cunningham, A. F., Knowles, T. J., Chng, S-S., Cole, J. A. & Henderson, I. R., 17 Aug 2017, In: Scientific Reports. 7, 1, 8608.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Membrane Lipids 100%
  • Protein Domains 91%
  • Carrier Proteins 76%
  • Homeostasis 66%
  • Membranes 53%
  19 Citations (Scopus)

  301 Downloads (Pure)

• Production, purification and characterization of recombinant, full-length human claudin-1

  Bonander, N., Jamshad, M., Oberthür, D., Clare, M., Barwell, J., Hu, K., Farquhar, M. J., Stamataki, Z., Harris, H. J., Dierks, K., Dafforn, T. R., Betzel, C., McKeating, J. A. & Bill, R. M., 2013, In: PLoS ONE. 8, 5, p. e64517

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Claudin-1 100%
  • Proteoliposome 94%
  • Hepatitis C virus 67%
  • Oligomer 55%
  • Purification 47%
  8 Citations (Scopus)

• SecA cotranslationally interacts with nascent substrate proteins in vivo

  Huber, D., Jamshad, M., Hanmer, R., Schibich, D., Doering, K., Marcomini, I., Kramer, G. & Bukau, B., Jan 2017, In: Journal of Bacteriology. 199, 2, e00622-16.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ribosomes 100%
  • Peptides 45%
  • Proteins 35%
  • Maltose-Binding Proteins 34%
  • Messenger RNA 27%
  33 Citations (Scopus)

  324 Downloads (Pure)

• Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins

  Jamshad, M., Grimard, V., Idini, I., Knowles, T. J., Dowle, M. R., Schofield, N., Sridhar, P., Lin, Y., Finka, R., Wheatley, M., Thomas, O. R. T., Palmer, R. E., Overduin, M., Govaerts, C., Ruysschaert, J., Edler, K. J. & Dafforn, T., Mar 2015, In: Nano Research. 8, 3, p. 774-789

  Research output: Contribution to journal › Article › peer-review

  • Lipid bilayers 100%
  • Detergents 84%
  • Styrene 69%
  • Structural analysis 62%
  • Nanoparticles 60%
  100 Citations (Scopus)

• Structural and functional analysis of the Escherichia coli acid-sensing histidine kinase EvgS

  Sen, H., Aggarwal, N., Ishionwu, C., Hussain, N., Parmar, C., Jamshad, M., Bavro, V. & Lund, P., 1 Sept 2017, In: Journal of Bacteriology. 199, 18, e00310-17.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Histidine Kinase 100%
  • Acids 52%
  • Escherichia coli 48%
  • Alkali Metals 29%
  • Dimerization 19%
  12 Citations (Scopus)

  179 Downloads (Pure)

• Structural characterization of CD81-Claudin-1 hepatitis C virus receptor complexes.

  Bonander, N., Jamshad, M., Hu, K., Farquhar, M., Stamataki, Z., Balfe, P., McKeating, J. & Bill, RM., 1 Apr 2011, In: Biochemical Society Transactions. 39, 2, p. 537-40 4 p.

  Research output: Contribution to journal › Article

  • Claudin-1 100%
  • Virus Receptors 95%
  • Tetraspanins 76%
  • Hepacivirus 64%
  • Claudins 48%
  5 Citations (Scopus)

• Surfactant-free purification of membrane protein complexes from bacteria: application to the staphylococcal penicillin-binding protein complex PBP2/PBP2a

  Paulin, S., Jamshad, M., Dafforn, T. R., Garcia-lara, J., Foster, S. J., Galley, N. F., Roper, D. I., Rosado, H. & Taylor, P. W., 18 Jul 2014, In: Nanotechnology. 25, 28, 285101.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carrier Proteins 100%
  • Purification 70%
  • Bacteria 69%
  • Surface active agents 68%
  • Proteins 57%
  40 Citations (Scopus)

  622 Downloads (Pure)

• Surfactant-free purification of membrane proteins with intact native membrane environment

  Jamshad, M., Lin, YP., Knowles, T., Parslow, R., Harris, C., Wheatley, M., Poyner, DR., Bill, RM., Thomas, O., Overduin, M. & Dafforn, T., 1 Jun 2011, In: Biochemical Society Transactions. 39, p. 813-818 6 p.

  Research output: Contribution to journal › Article

  • Surface-Active Agents 100%
  • Membrane Proteins 79%
  • Purification 64%
  • Membranes 57%
  • Environment 54%
  69 Citations (Scopus)

• The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity

  Jamshad, M., Knowles, T. J., White, S. A., Ward, D. G., Mohammed, F., Rahman, K. F., Wynne, M., Hughes, G. W., Kramer, G., Bukau, B. & Huber, D., 27 Jun 2019, In: eLife. 8, 23 p., e48385.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bacterial Translocation 100%
  • Ribosomes 78%
  • Adenosine Triphosphatases 75%
  • Metals 48%
  • Protein Binding 37%
  4 Citations (Scopus)

  202 Downloads (Pure)

• The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms

  Garvin, A. J., Walker, A. K., Densham, R. M., Chauhan, A. S., Stone, H. R., Mackay, H. L., Jamshad, M., Starowicz, K., Daza-Martin, M., Ronson, G. E., Lanz, A. J., Beesley, J. F. & Morris, J. R., 1 Mar 2019, In: Genes & Development. 33, 5-6, p. 333-347 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • 1,2-di-(4-sulfamidophenyl)-4-butylpyrazolidine-3,5-dione 100%
  • Sumoylation 92%
  • Homologous Recombination 77%
  • Personnel Selection 51%
  • Double-Stranded DNA Breaks 39%
  12 Citations (Scopus)

  271 Downloads (Pure)

• Yeast transformation to generate high-yielding clones.

  Jamshad, M. & Darby, RA., 1 Jan 2012, In: Methods in molecular biology. 866, p. 57-63 7 p.

  Research output: Contribution to journal › Article

  • Yeasts 100%
  • Clone Cells 98%
  • DNA 55%
  • Electroporation 29%
  • Cell Membrane 18%
  1 Citation (Scopus)