Regulation of the 'molecular scissor' ADAM10 by tetraspanins: implications for human diseases such as cancer, Alzheimer's disease, asthma and inflammatory diseases such as heart attack and stroke.
Techniques include cell culture and CRISPR/Cas9 genome editing, flow cytometry, co-immunoprecipitation and western blotting using the Odyssey Infrared Imaging System, and advanced fluorescence microscopy.
20012024
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