Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Investigating the effects of post-exercise serum treatments on APP processing in iPSC-derived neurons and astrocytes
Elsworthy, R. J., Spencer, F. S. E., Allen, S., Dunleavy, C., Whitham, M., Lucas, S. J. E., Hill, E. J. & Aldred, S., 2 Mar 2026, In: International Journal of Biochemistry and Cell Biology. 192, 12 p., 106920.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
A Multiscale In Silico Analysis Identifies Plasma Levels of miR-223-3p as an Emerging Biomarker of Cardiac Response to Acute Exercise and Training in Olympic Medallists
Fernandez-Vivero, D., Terrados, N., Pinto-Hernandez, P., Noguero-Lopez, C., Fernandez-Garcia, B., Whitham, M., Iglesias-Gutierrez, E. & Fernandez-Sanjurjo, M., 16 Jun 2025, In: Scandinavian Journal of Medicine and Science in Sports. 35, 6, 11 p., e70092.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Downloads (Pure) -
Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice
Hjorth, M., Egan, C. L., Telles, G. D., Pal, M., Gallego-Ortega, D., Fuller, O. K., McLennan, E. D., Gillis, R. D., Oh, T. G., Muscat, G. E. O., Tegegne, S., Mah, M. S. M., Skhinas, J., Estevez, E., Adams, T. E., McKay, M. J., Molloy, M., Watt, K. I., Qian, H. & Gregorevic, P. & 11 others, , Dec 2025, In: Journal of Sport and Health Science. 14, 18 p., 100991.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Downloads (Pure) -
ER stress disrupts insulin release in murine models of type 2 diabetes by impairing retromer action and constitutive secretion
Sue, N., Thai, L. M., Boslem, E., Chu, K. Y., Yan, C., Mackin, L., Hughes, W. E., Fontaine-Titley, A., Barkauskas, D., Cottle, L., Thomas, H. E., Schmitz-Peiffer, C., Shi, Y. C., Timpson, P., Herrmann, D., Whitham, M. & Biden, T. J., 27 May 2025, In: Cell Reports. 44, 5, 21 p., 115691.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Downloads (Pure) -
Extracellular vesicles contribute to the beneficial effects of exercise training in APP/PS1 mice
Fuller, O. K., McLennan, E. D., Egan, C. L., Perera, N., Terry, L. V., Pyun, J., de Mendonca, M., Telles, G. D., Smeuninx, B., Burrows, E. L., Siddiqui, G., Creek, D. J., Scott, J. W., Pearen, M. A., Fonseka, P., Nicolazzo, J. A., Mathivanan, S., Hannan, A. J., Ramm, G. A. & Whitham, M. & 1 others, , 21 Feb 2025, In: iScience. 28, 2, 23 p., 111752.Research output: Contribution to journal › Article › peer-review
Open AccessFile42 Downloads (Pure)
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Building an iPSC-based model to investigate the molecular effects of exercise on APP processing
Di Maio, A. (Co-Investigator), Whitham, M. (Co-Investigator), Elsworthy, R. (Principal Investigator) & Aldred, S. (Co-Investigator)
1/04/25 → 31/03/27
Project: Research
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Investigating the molecular effects of exercise on APP processing utilising highly characterised iPSC neurons and astrocytes
Aldred, S. (Co-Investigator), Elsworthy, R. (Principal Investigator) & Whitham, M. (Co-Investigator)
1/10/23 → 30/09/24
Project: Research
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WT ISSF: Alex Seabright Accelerator Fellowship
Whitham, M. (Principal Investigator)
1/10/20 → 31/03/22
Project: Research
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Characterisation of extracellular vesicle tropism via SILAC pulse chase mass spectrometry
Whitham, M. (Principal Investigator)
1/09/19 → 1/03/22
Project: Research
Datasets
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Effect of treadmill exercise on the mouse gastrocnemius proteome assessed via spike-in SILAC quantitative proteomics
Whitham, M. (Creator), University of Birmingham, 1 Dec 2023
DOI: 10.25500/edata.bham.00001030
Dataset
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Adipocyte specific deletion of IL-6 does not attenuate obesity-induced weight gain or glucose intolerance in mice. Supplementary Data
Whitham, M. (Creator), University of Birmingham, 2019
DOI: 10.25500/edata.bham.00000338
Dataset
Press/Media
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Publications with Impact: "The Small Talk of Exercise"
1/04/18
1 Media contribution
Press/Media: Press / Media
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Research suggests a reason for the widespread benefits of exercise
12/02/18
1 Media contribution
Press/Media: Press / Media
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