Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
University of Sheffield
1 Aug 2012 → 1 May 2016
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Dive into the research topics where Mark R Thomas is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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GPVI inhibition: Advancing antithrombotic therapy in cardiovascular disease
Slater, A., Khattak, S. & Thomas, M. R., 7 Mar 2024, (E-pub ahead of print) In: European heart journal. Cardiovascular pharmacotherapy. 9 p., pvae018.Research output: Contribution to journal › Article › peer-review
Open AccessFile82 Downloads (Pure) -
Impact of antiplatelet therapy on microvascular thrombosis during ST-elevation myocardial infarction
Khattak, S., Townend, J. N. & Thomas, M. R., 13 Mar 2024, In: Frontiers in Molecular Biosciences. 11, 12 p., 1287553.Research output: Contribution to journal › Review article › peer-review
Open AccessFile101 Downloads (Pure) -
Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2 & PRN473 reduces venous thrombosis formation in mice
Smith, C., Campos, J., Brown, H., Ivanova, V.-S., Harbi, M., Garcia Quintanilla, L., Jossi, S., Perez-Toledo, M., Rookes, K., Brill, A., Theodore, L., Owens, T., LaStant, J., Foulke, M. C., Mukai, S., Francesco, M., Storek, M., Hicks, A., Langrish, C. & Nunn, P. A. & 5 others, , 5 Jul 2024, (E-pub ahead of print) In: Blood Advances. bloodadvances.2024012713.Research output: Contribution to journal › Article › peer-review
Open Access -
Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy JTH
Alenazy, F., Harbi, M., Kavanagh, D., Price, J., Brady, P., Hargreaves, O., Harrison, P., Slater, A., Tiwari, A., Nicolson, P., Connolly, D., Kirchhof, P., Kalia, N., Jandrot-Perrus, M., Mangin, P. H., Watson, S. & Thomas, M. R., 17 Oct 2023, In: Journal of thrombosis and haemostasis : JTH. 21, 11, p. 3236-3251 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile100 Downloads (Pure) -
Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization
Damaskinaki, F.-N., Jooss, N. J., Martin, E. M., Clark, J. C., Thomas, M. R., Poulter, N. S., Emsley, J., Kellam, B., Watson, S. P. & Slater, A., Feb 2023, In: Journal of thrombosis and haemostasis : JTH. 21, 2, p. 317-328 12 p.Research output: Contribution to journal › Article › peer-review
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MRC IAA (Internal) Further development and characterisation of a bispecific nanobody to GPVI and human serum albumin as a novel anti-thrombotic therapy
Poulter, N. (Principal Investigator), Thomas, M. R. (Co-Investigator), Slater, A. (Co-Investigator) & Watson, S. (Co-Investigator)
1/03/25 → 31/03/26
Project: Research Councils
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MRC IAA Development of a bivalent nanobody to GPVI and human albumin as a novel anti-thrombotic therapy
Watson, S. (Co-Investigator), Thomas, M. R. (Co-Investigator), Slater, A. (Co-Investigator) & Poulter, N. (Principal Investigator)
1/02/24 → 31/05/25
Project: Research Councils
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LIBERATE-FULL- A phase IIb, randomised, double-bLInd, placeBo-controllEd tRiAl To invEstigate the safety, efficacy and mechanism of inhibiting platelet GPVI as a treatment for ST-elevation myocardial infarction
Barton, D. (Co-Investigator), Thomas, M. R. (Principal Investigator), Nicolson, P. (Co-Investigator), Bach, S. (Co-Investigator), Watson, S. (Co-Investigator), Pirrie, S. (Co-Investigator) & Homer, V. (Researcher)
1/04/22 → 31/03/25
Project: Research
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The effect of Btk inhibition on platelet activation and thrombosis (focussing on hepatic portal vein thrombosis)
Watson, S. (Co-Investigator), Thomas, M. R. (Co-Investigator), Nicolson, P. (Principal Investigator) & Chauhan, A. (Co-Investigator)
26/04/20 → 31/05/23
Project: Research
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Measurement of Extracellular Vesicles in Cardiovascular Disease by a Novel Interferometric Imaging method
Thomas, M. R. (Researcher) & Harrison, P. (Principal Investigator)
1/01/20 → 31/12/22
Project: Research