Research output per year
Research output per year
Personal profile
Qualifications
Ph.D (Medicinal Chemistry), Manchester Pharmacy School, The University of Manchester, 2009
M.Phil (Medicinal Chemistry), Manchester Pharmacy School, The University of Manchester, 2006
B.Pharm, Dr. M.G.R Medical University, Madras, India, 1999
Biography
BPharm (1999) from Dr MGR Medical University, India. MPhil (2006) and PhD (2009) from the University of Manchester. Later worked as a Research Associate then Research Fellow in Radiochemistry at the Wolfson Molecular Imaging Centre (WMIC), the University of Manchester. CRUK Research Travel Fellowship was awarded to work at the Department of Radiology and Oncology, Johns Hopkins University, USA. In addition, I had worked at the R&D centres of Pharma and Medical diagnostic companies.
Currently working as a Research Fellow in Radiochemistry at the Department of Chemical Engineering.
Research interests
Radiochemist with strong experiences and interests in design, multi-step synthesis, purification, characterisation of organic compounds and radiotracers using Fluorine Chemistry (18F/19F) and other labelling strategies (11C, 68Ga, 124I, 123I, 99mTc, 13C) of bioactive and precursor compounds for Positron/Single-Photon/Magnetic Resonance imaging (PET/SPECT/MR) research.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Computational studies on selected macrolides active against Escherichia coli combined with the NMR study of tylosin A in deuterated chloroform
Arsic, B., Barber, J., Cikos, A., Kadirvel, M., Kostic, E., McBain, A. J., Milicevic, J., Oates, A. & Regan, A., 26 Oct 2022, In: Molecules. 27, 21, 21 p., 7280.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure) -
SAR of novel 3-arylisoquinolinones: meta-substitution on the aryl ring dramatically enhances antiproliferative activity through binding to microtubules
A. Elhemely, M., Begath, A., El-Sayed, S., Burusco, K., Kadirvel, M., Tirella, A., Finegan, K., Bryce, R., Stratford, I. & Freeman, S., 24 Mar 2022, In: Journal of Medicinal Chemistry. 65, 6, p. 4783-4797 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile46 Downloads (Pure) -
Impact of long-term quorum sensing inhibition on uropathogenic Escherichia coli
Henly, E. L., Norris, K., Rawson, K., Zoulias, N., Jaques, L., Chirila, P. G., Parkin, K. L., Kadirvel, M., Whiteoak, C., Lacey, M. M., Smith, T. J. & Forbes, S., Apr 2021, In: Journal of Antimicrobial Chemotherapy. 76, 4, p. 909-919 11 p.Research output: Contribution to journal › Article › peer-review
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Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2)
Hussein, B., Ikhmais, B., Kadirvel, M., Magwaza, R. N., Halbert, G., Bryce, R. A., Stratford, I. J. & Freeman, S., 15 Nov 2019, In: European Journal of Medicinal Chemistry. 182, 11 p., 111649.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Evaluation of analogues of furan-amidines as inhibitors of NQO2
Alnabulsi, S., Hussein, B., Santina, E., Alsalahat, I., Kadirvel, M., Magwaza, R. N., Bryce, R. A., Schwalbe, C. H., Baldwin, A. G., Russo, I., Stratford, I. J. & Freeman, S., 1 May 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 8, p. 1292-1297 6 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus)
Prizes
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CRUK Research Travel Award
Kadirvel, Manikandan (Recipient), 11 Apr 2016
Prize: Prize (including medals and awards)
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JCP Young Researcher Award
Kadirvel, Manikandan (Recipient), 15 Jul 2016
Prize: Prize (including medals and awards)